Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Identification and functional evaluation of candidate mutations related to genome destabilization in uninvolved, non-tumor mammary glandular tissue samples from breast cancer patients.

2015/19/B/NZ2/03216

Keywords:

breast cancer genetyka genomika genome destabilization

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_5: Cell genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Arkadiusz Piotrowski 

Number of co-investigators in the project: 7

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 563 380 PLN

Project start date (Y-m-d): 2016-09-30

Project end date (Y-m-d): 2021-09-29

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Inkubator do hodowli komórkowych.
  2. Inkubator do hodowli komórkowych (50 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing.
    Authors:
    Anna Kostecka, Tomasz Nowikiewicz, Paweł Olszewski, Magdalena Koczkowska, Monika Horbacz, Monika Heinzl,Maria Andreou, Renato Salazar, Theresa Mair, Piotr Madanecki, Magdalena Gucwa, Hanna Davies, Jarosław Skokowski, Patrick G. Buckley, Rafał Pęksa, Ewa Śrutek, Łukasz Szylberg, Johan Hartman, Michał Jankowski, Wojciech Zegarski, Irene Tiemann-Boege, Jan P. Dumanski, Arkadiusz Piotrowski
    Academic press:
    Nature Partner Journal Breast Cancer (NPJ Breast Cancer) (rok: 2022, tom: 8, strony: 76), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41523-022-00443-9 - link to the publication
  2. High-Throughput Tabular Data Processor - Platform independent graphical tool for processing large data sets
    Authors:
    Madanecki P, Bałut 1, Buckley PG, Ochocka JR, Bartoszewski R, Crossman DK, Messiaen LM, Piotrowski A
    Academic press:
    PLoS One (rok: 2018, tom: 13(2), strony: e0192858), Wydawca: PUBLIC LIBRARY OF SCIENCE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0192858 - link to the publication

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