Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Cytoplasmatic roadblocks in cell fate reprogramming: from players to molecular mechanisms

2015/19/B/NZ3/02412

Keywords:

germline oocyte zygotic genome activation RNA binding proteins post-transcriptional regulation Caenorhabditis elegans genetics

Descriptors:

  • NZ3_13: Developmental biology in animals
  • NZ2_1: Molecular genetics
  • NZ1_1: Molecular biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Chemii Bioorganicznej Polskiej Akademii Nauk

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Rafał Ciosk 

Number of co-investigators in the project: 5

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 787 087 PLN

Project start date (Y-m-d): 2016-11-30

Project end date (Y-m-d): 2020-11-29

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mikroskop fluorescencyjny, kompletnie wyposażony, Zeiss Axio Imager.Z2 lub podobny. (300 000 PLN)
  2. Transiluminator AS.
  3. Monitor do mikroskopu Zeiss.
  4. Fluorescencyjny mikroskop manipulacyjny, kompletnie wyposażony, SteREO Discovery.V12 lub podobny. (120 000 PLN)
  5. Zestaw komputerowy z oprogramowaniem do mikroskopu Nikon.

Information in the final report

  • Publication in academic press/journals (3)
  1. PRP-19, a conserved pre-mRNA processing factor and E3 ubiquitin ligase, inhibits the nuclear accumulation of GLP-1/Notch intracellular domain
    Authors:
    Gutnik S, Thomas Y, Guo Y, Stoecklin J, Neagu A, Pintard L, Merlet J, Ciosk R
    Academic press:
    Biology Open (rok: 2018, tom: nie dotyczy, strony: 16;7(7). pii: bio034066), Wydawca: COMPANY BIOLOGISTS LTD.
    Status:
    Published
    DOI:
    10.1242/bio.034066 - link to the publication
  2. The CSR-1 endogenous RNAi pathway ensures accurate transcriptional reprogramming during the oocyte-to-embryo transition in Caenorhabditis elegans.
    Authors:
    Christina Fassnacht, Cristina Tocchini, Pooja Kumari, Dimos Gaidatzis, Michael B. Stadler and Rafal Ciosk
    Academic press:
    PLoS Genetics (rok: 2018, tom: 14, strony: 26;14(3):e1007252), Wydawca: PUBLIC LIBRARY SCIENCE
    Status:
    Published
    DOI:
    10.1371/journal.pgen.1007252 - link to the publication
  3. Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition.
    Authors:
    Pooja Kumari, Florian Aeschimann, Dimos Gaidatzis, Jeremy J. Keusch, Pritha Ghosh, Anca Neagu, Katarzyna Pachulska-Wieczorek, Janusz M. Bujnicki, Heinz Gut, Helge Großhans and Rafal Ciosk.
    Academic press:
    Nature Communications (rok: 2018, tom: brak, strony: 19;9(1):1549), Wydawca: NATURE PUBLISHING GROUP
    Status:
    Published
    DOI:
    10.1038/s41467-018-03920-7 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy