Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Fibrin clot properties in acute pulmonary embolism.

2015/19/B/NZ5/02215

Keywords:

pulmonary embolism fibrin fibrin clot properties

Descriptors:

  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Anetta Undas 

Number of co-investigators in the project: 6

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 658 790 PLN

Project start date (Y-m-d): 2016-07-14

Project end date (Y-m-d): 2021-07-13

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Spektrofotometr do mikroobjętości (NanoDrop).
  2. System do dokumentacji i analizy Westrn Blot oraz żeli 1D (140 000 PLN)
  3. Zamrażarka medyczna-86C MDF.
  4. Pipeta Xplorer.
  5. Łaźnia wodna (10 000 PLN)
  6. Suszarka w punkcie krytycznym.
  7. pH-metr (10 000 PLN)

Information in the final report

  • Publication in academic press/journals (11)
  • Articles in post-conference publications (3)
  1. Effect of enoxaparin on plasma fibrin clot properties and fibrin structure in patients with acute pulmonary embolism
    Authors:
    Michał Ząbczyk, Joanna Natorska, Krzysztof P Malinowski, Anetta Undas
    Academic press:
    Vascul Pharmacol (rok: 2020, tom: 133-134, strony: 106783), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.vph.2020.106783 - link to the publication
  2. Loose Fibrin Clot Structure and Increased Susceptibility to Lysis Characterize Patients with Central Acute Pulmonary Embolism: The Impact of Isolated Embolism
    Authors:
    Michał Ząbczyk, Joanna Natorska, Agnieszka Janion-Sadowska, Agnieszka Metzgier-Gumiela, Mateusz Polak, Krzysztof Plens, Marianna Janion, Grzegorz Skonieczny, Katarzyna Mizia-Stec, Anetta Undas
    Academic press:
    Thromb Haemost (rok: 2020, tom: brak, strony: brak), Wydawca: Thieme
    Status:
    Published
    DOI:
    10.1055/s-0040-1718762 - link to the publication
  3. Fibrinogen β chain and FXIII polymorphisms affect fibrin clot properties in acute pulmonary embolism
    Authors:
    Adrianna Klajmon, Jakub Chmiel, Michał Ząbczyk, Ewa Wypasek, Krzysztof P. Malinowski, Anetta Undas, Joanna Natorska
    Academic press:
    Eur J Clin Invest (rok: 2021, tom: brak, strony: e13718), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/eci.13718 - link to the publication
  4. Plasma fibrin clot proteomics in patients with acute pulmonary embolism: Association with clot properties
    Authors:
    Agata Hanna Bryk, Joanna Natorska, Michał Ząbczyk, Katharina Zettl, Jacek R Wiśniewski, Anetta Undas
    Academic press:
    J Proteomics (rok: 2020, tom: 229, strony: 103946), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jprot.2020.103946 - link to the publication
  5. Right ventricular echocardiographic parameters associated with prothrombotic abnormalities in normotensive patients with acute pulmonary embolism
    Authors:
    Agnieszka Janion-Sadowska, Paweł Rostoff, Michał Ząbczyk, Magdalena Chrapek, Marianna Janion, Anetta Undas
    Academic press:
    International Journal of Cardiology (rok: 2021, tom: 333, strony: 195-201), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijcard.2021.02.087 - link to the publication
  6. Factor XIII and Fibrin Clot Properties in Acute Venous Thromboembolism
    Authors:
    Michał Ząbczyk, Joanna Natorska, Anetta Undas
    Academic press:
    Int J Mol Sci (rok: 2021, tom: 22, strony: 1607), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22041607 - link to the publication
  7. Isoprostane-8 and GDF-15 as novel markers of post-PE syndrome: relation with prothrombotic factors
    Authors:
    Michał Ząbczyk, Joanna Natorska, Agnieszka Janion-Sadowska, Agnieszka Metzgier-Gumiela, Mateusz Polak, Krzysztof Plens, Marianna Janion, Grzegorz Skonieczny, Katarzyna Mizia-Stec, Anetta Undas
    Academic press:
    Eur J Clin Invest (rok: 2021, tom: brak, strony: e13660), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/eci.13660 - link to the publication
  8. Elevated Lactate Levels in Acute Pulmonary Embolism Are Associated with Prothrombotic Fibrin Clot Properties: Contribution of NETs Formation
    Authors:
    Michał Ząbczyk, Joanna Natorska, Agnieszka Janion-Sadowska, Krzysztof P Malinowski, Marianna Janion, Anetta Undas
    Academic press:
    J Clin Med (rok: 2020, tom: 9, strony: 953), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm9040953 - link to the publication
  9. Plasma fibrin clot structure and thromboembolism: clinical implications
    Authors:
    Ząbczyk M, Undas A
    Academic press:
    Pol Arch Intern Med (rok: 2017, tom: 127, strony: 873-881), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.4165 - link to the publication
  10. Plasma fibrin clots of pulmonary embolism patients present increased amounts of factor XIII and alpha2-antiplasmin at 3 months' anticoagulation since the acute phase
    Authors:
    M Zabczyk, J Natorska, Z Bagoly, F Sarkady, B Barath, E Katona, A Bryk, K Zettl, J R Wisniewski, A Undas
    Academic press:
    J Physiol Pharmacol (rok: 2020, tom: 71, strony: 519-524), Wydawca: Polish Physiological Society
    Status:
    Published
    DOI:
    10.26402/jpp.2020.4.07 - link to the publication
  11. Prothrombotic fibrin clot properties associated with NETs formation characterize acute pulmonary embolism patients with higher mortality risk
    Authors:
    Michał Ząbczyk, Joanna Natorska, Agnieszka Janion-Sadowska, Agnieszka Metzgier-Gumiela, Mateusz Polak, Krzysztof Plens, Marianna Janion, Grzegorz Skonieczny, Katarzyna Mizia-Stec, Anetta Undas
    Academic press:
    Scientific Reports (rok: 2020, tom: 10, strony: 11433), Wydawca: Nature Publishing Group
    Status:
    Published
    DOI:
    10.1038/s41598-020-68375-7 - link to the publication
  1. Ryzyko wczesnego zgonu w ostrej zatorowości płucnej jest związane z wydłużonym czasem lizy skrzepu: rola NETozy
    Authors:
    Michał Ząbczyk, Joanna Natorska, Agnieszka Janion‑Sadowska, Agnieszka Metzgier‑Gumiela, Marianna Janion, Grzegorz Skonieczny, Anetta Undas
    Conference:
    The 23rd International Congress of the Polish Cardiac Society, September 26–28, 2019, Katowice, Poland (rok: 2019, ), Wydawca: Kardiologia Polska
    Data:
    konferencja 26-28.09.2019
    Status:
    Published
  2. Fibrinogen B Arg448Lys and Factor XIII Val34Leu Polymorphisms Are Associated with Prothrombotic Fibrin Clot Properties in Patients with Acute Pulmonary Embolism
    Authors:
    A. Klajmon, J. Chmiel, M. Ząbczyk, J. Natorska, A. Undas
    Conference:
    ISTH Congress (rok: 2021, ), Wydawca: Wiley
    Data:
    konferencja 17-21.07.2021
    Status:
    Published
    DOI:
    link to the publication
  3. Histidine-rich Glycoprotein Levels Contribute to Prolonged Clot Lysis Time in Acute Pulmonary Embolism
    Authors:
    Patrick Bladek, Michal Zabczyk, Joanna Natorska, Anetta Undas
    Conference:
    International Society on Thrombosis and Haemostasis 2020 Congress (rok: 2020, ), Wydawca: Wiley Online Library
    Data:
    konferencja 12-14.07.2020
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy