Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Searching for genetic determinants of malignancy in follicular thyroid lesions employing genomic screening

2015/19/N/NZ5/02257

Keywords:

follicular thyroid cancer follicular thyroid adenoma next-generation sequencing molecular inversion probe genome-based high throughput sreening

Descriptors:

  • NZ5_5: Diagnostics in human diseases
  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu, Wydział Lekarski II

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Martyna Borowczyk 

Number of co-investigators in the project: 3

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 150 000 PLN

Project start date (Y-m-d): 2016-08-16

Project end date (Y-m-d): 2019-08-15

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (2)
  1. High incidence of FLT3 mutations in follicular thyroid cancer – potential therapeutic target in patients with advanced disease stage
    Authors:
    Martyna Borowczyk*, Ewelina Szczepanek-Parulska*, Szymon Dębicki, Bartłomiej Budny, Małgorzata Janicka-Jedyńska, Lidia Gil, Frederik A. Verburg, Dorota Filipowicz, Elżbieta Wrotkowska, Blanka Majchrzycka, Andrzej Marszałek, Katarzyna Ziemnicka, Marek Ruchała
    Academic press:
    Therapeutic Advances in Medical Oncology (rok: 2020, tom: 12, strony: 45306), Wydawca: SAGE Journals
    Status:
    Published
    DOI:
    10.1177/1758835920907534 - link to the publication
  2. Differences in mutational profile between follicular thyroid carcinoma and follicular thyroid adenoma identified using next generation sequencing
    Authors:
    Martyna Borowczyk, Ewelina Szczepanek-Parulska, Szymon Dębicki, Bartłomiej Budny, Frederik A. Verburg, Dorota Filipowicz, Barbara Więckowska, Małgorzata Janicka-Jedyńska, Lidia Gil, Katarzyna Ziemnicka, Marek Ruchała
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20, strony: pii: E3126), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20133126 - link to the publication
  3. Evaluation of 167 Gene Expression Classifier (GEC) and ThyroSeq v2 Diagnostic Accuracy in the Preoperative Assessment of Indeterminate Thyroid Nodules: Bivariate/HROC Meta-analysis
    Authors:
    Martyna Borowczyk, Ewelina Szczepanek-Parulska, Michał Olejarz, Barbara Więckowska, Frederik A. Verburg, Szymon Dębicki, Bartłomiej Budny, Małgorzata Janicka-Jedyńska, Katarzyna Ziemnicka, Marek Ruchała
    Academic press:
    Endocrine Pathology (rok: 2019, tom: 1,25069444444444, strony: 45519), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12022-018-9560-5 - link to the publication
  4. The genetic heterogeneity of indeterminate thyroid nodules assessed preoperatively with next generation sequencing reflects the diversity of the final histopathological diagnoses
    Authors:
    Martyna Borowczyk, Ewelina Szczepanek-Parulska, Szymon Dębicki, Bartłomiej Budny, Frederik A. Verburg, Dorota Filipowicz, Elżbieta Wrotkowska, Małgorzata Janicka-Jedyńska, Barbara Więckowska, Lidia Gil, Katarzyna Ziemnicka, Marek Ruchała
    Academic press:
    Polish Archives of Internal Medicine (rok: 2019, tom: -, strony: -), Wydawca: Medycyna Praktyczna
    Status:
    Published
    DOI:
    10.20452/pamw.14979 - link to the publication
  1. New markers of follicular thyroid cancer found with wide-panel next-generation sequencing
    Authors:
    Martyna Borowczyk, Ewelina Szczepanek-Parulska, Szymon Dębicki, Bartłomiej Budny, Małgorzata Janicka-Jedyńska, Elżbieta Wrotkowska, Blanka Majchrzycka, Katarzyna Ziemnicka, Marek Ruchała
    Conference:
    20th European Congress of Endocrinology (rok: 2018, ), Wydawca: bioscientifica
    Data:
    konferencja 19-22.05.2018
    Status:
    Published
  2. TP53 and FLT3 may become candidate markers for detecting malignancy in follicular lesions
    Authors:
    Martyna Borowczyk, Ewelina Szczepanek-Parulska, Szymon Dębicki, Bartłomiej Budny, Frederik A Verburg, Małgorzata Janicka-Jedyńska, Barbara Więckowska, Lidia Gil, Dorota Filipowicz, Katarzyna Ziemnicka, Marek Ruchała
    Conference:
    21st European Congress of Endocrinology (rok: 2019, ), Wydawca: bioscientifica
    Data:
    konferencja 18-21.05.2019
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy