Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effects of maternal high-fat or high-sugar diet on the impaired NMDA receptor composition and regulation in offspring in context of memory deficits.

2015/19/D/NZ7/00082

Keywords:

glutamate system high-fat diet high-sugar diet memory deficits NMDA

Descriptors:

  • NZ3_7: Signal transduction
  • NZ7_4: Prevention in population health

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum, Wydział Farmaceutyczny

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Lucyna Pomierny-Chamioło 

Number of co-investigators in the project: 6

Call: SONATA 10 - announced on 2015-09-15

Amount awarded: 588 058 PLN

Project start date (Y-m-d): 2016-07-11

Project end date (Y-m-d): 2021-01-10

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer stacjonarny iMac Retina.
  2. Dysk zewnętrzny (466 PLN)
  3. Oprogramowanie statystyczne GraphPad - licencja.
  4. Wysokoobrotowa wirówka z chłodzeniem, CRF do 65 000xg z rotorami (55 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Disruption of Glutamate Homeostasis in the Brain of Rat Off-spring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet
    Authors:
    Jozef Mizera, Bartosz Pomierny, Anna Sadakierska-Chudy, Beata Bystrowska, Lucyna Pomierny-Chamiolo
    Academic press:
    Nutrients (rok: 2022, tom: 14(11), strony: 2184), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu14112184 - link to the publication
  2. Maternal High-Fat diet During Pregnancy and Lactation Disrupts NMDA Receptor Expression and Spatial Memory in the Offspring
    Authors:
    Jozef Mizera, Grzegorz Kazek, Bartosz Pomierny, Beata Bystrowska, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamiolo
    Academic press:
    Molecular Neurobiology (rok: 2022, tom: 45474, strony: e), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-022-02908-1 - link to the publication
  3. Maternal high-sugar diet results in NMDA receptors abnormalities and cognitive impairment in rat offspring
    Authors:
    Jozef Mizera, Grzegorz Kazek, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamioło
    Academic press:
    The FASEB Journal (rok: 2021, tom: 35, strony: e21547), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1096/fj.202002691R - link to the publication

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