Effects of maternal high-fat or high-sugar diet on the impaired NMDA receptor composition and regulation in offspring in context of memory deficits.

2015/19/D/NZ7/00082

Keywords

Descriptors

  • NZ3_7: Przekaźnictwo sygnału
  • NZ7_4: Prewencja populacyjna

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Lucyna Pomierny-Chamioło

Number of co-investigators in the project: 6

Call

SONATA 10 – announced on 2015-09-15

Amount awarded
588 058 PLN
Project start date
2016-07-11
Project end date
2021-01-10
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dysk zewnętrzny. Cost: 466 PLN
  2. Komputer stacjonarny iMac Retina.
  3. Oprogramowanie statystyczne GraphPad - licencja.
  4. Wysokoobrotowa wirówka z chłodzeniem, CRF do 65 000xg z rotorami. Cost: 55 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Maternal high-sugar diet results in NMDA receptors abnormalities and cognitive impairment in rat offspring

    Authors:
    Jozef Mizera, Grzegorz Kazek, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamioło
    Academic press:
    The FASEB Journal (year: 2021, volume: 35, pages: e21547), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1096/fj.202002691R – link to the publication
  2. Maternal High-Fat diet During Pregnancy and Lactation Disrupts NMDA Receptor Expression and Spatial Memory in the Offspring

    Authors:
    Jozef Mizera, Grzegorz Kazek, Bartosz Pomierny, Beata Bystrowska, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamiolo
    Academic press:
    Molecular Neurobiology (year: 2022, volume: 46204, pages: e), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-022-02908-1 – link to the publication
  3. Disruption of Glutamate Homeostasis in the Brain of Rat Off-spring Induced by Prenatal and Early Postnatal Exposure to Maternal High-Sugar Diet

    Authors:
    Jozef Mizera, Bartosz Pomierny, Anna Sadakierska-Chudy, Beata Bystrowska, Lucyna Pomierny-Chamiolo
    Academic press:
    Nutrients (year: 2022, volume: 14(11), pages: 2184), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/nu14112184 – link to the publication

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