Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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NMDA receptor independent, acetylcholine induced bursting activity of midbrain dopaminergic neurons - in vivo electrophysiological and pharmacological studies.

2015/19/N/NZ4/00960

Keywords:

cholinegic receptors dopaminergic neurons bursting activity

Descriptors:

  • NZ4_7: Neurophysiology
  • NZ4_9: Systems neurobiology
  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński, Wydział Biologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Magdalena Walczak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 10 - announced on 2015-09-15

Amount awarded: 149 160 PLN

Project start date (Y-m-d): 2016-08-04

Project end date (Y-m-d): 2020-08-03

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. obiektyw i obudowa lampy halogenowej.
  2. System do jontoforetycznego podawania substancji (21 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (5)
  1. Midbrain dopaminergic neuron activity across alternating brain states of urethane anaesthetized rat.
    Authors:
    Walczak M., Błasiak T.
    Academic press:
    European Journal of Neuroscience (rok: 2017, tom: 45, strony: 1068–1077), Wydawca: Federation of European Neuroscience Societies and John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/ejn.13533 - link to the publication
  2. Several behavioral traits relevant for alcoholism are controlledby ɣ2 subunit containing GABAAreceptors on dopamineneurons in mice
    Authors:
    Andrea Stojakovic, Magdalena Walczak, Przemysław E Cieślak, Aleksandra Trenk, Johan Sköld, Joanna Zajdel,Elahe Mirrasekhian, Camilla Karlsson, Annika Thorsell, Markus Heilig, Jan Rodriguez Park itna, Tomasz Błasiak andDavid Engblom
    Academic press:
    Neuropsychopharmacology (rok: 2018, ), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41386-018-0022-z - link to the publication
  1. NMDA independent complex bursts in dopaminergic neurons in response to cholinergic agonists administration - in vivo electrophysiological and pharmacological studies on NR- 1DATCreERT2 mice
    Authors:
    Magdalena Walczak, Łukasz Szumiec, Jan Rodriguez Parkitna, Tomasz Błasiak
    Conference:
    8th conference Aspects of Neuroscience (rok: 2018, ), Wydawca: Wydział Biologii Uniwersytet Warszawski
    Data:
    konferencja 23-25.11
    Status:
    Published
  2. Carbachol-induced NMDA-independent complex bursting of midbrain dopaminergic neurons – in vivo electrophysiological and pharmacological studies on NR1DATCreERT2 mice
    Authors:
    Magdalena Walczak, Jan Rodriguez Parkitna, Tomasz Błasiak
    Conference:
    11th Conference on Electrophysiological Techniques in Bioelectricity Research: from ion channels to neural networks (rok: 2018, ), Wydawca: Nencki Institute of Experimentsl Biology, Polish Academy of Science
    Data:
    konferencja 25-26.05
    Status:
    Published
  3. Influence of carbachol on electrical activity of midbrain dopaminergic neurons – in vivo studies on urethane anaesthetized mice
    Authors:
    Magdalena Walczak, Łukasz Szumiec, Jan Rodriguez Parkitna, Tomasz Błasiak
    Conference:
    Neuronus 2018 IBRO Neuroscience Forum (rok: 2018, ), Wydawca: STUDENT NEUROSCIENCE SOCIETY 'NEURONUS' INSTITUTE OF ZOOLOGY AND BIOMEDICAL RESEARCH OF THE JAGIELLONIAN UNIVERSITY
    Data:
    konferencja 20-22.04
    Status:
    Published
  4. Influence of carbachol on activity level and pattern of dopaminergic neurons – in vivo studies on urethane anaesthetized mice
    Authors:
    Magdalena Walczak, Jan Rodriguez Parkitna, Tomasz Błasiak
    Conference:
    7th conference Aspects of Neuroscience (rok: 2017, ), Wydawca: Wydział Biologii Uniwersytet Warszawski
    Data:
    konferencja 24-26.11
    Status:
    Published
  5. NMDA-independent mechanism of bursting activity in dopaminergic neurons – in vivo studies on urethane anaesthetized mice
    Authors:
    Magdalena Walczak, Łukasz Szumiec, Jan Rodriguez Parkitna, Tomasz Błasiak
    Conference:
    11 FENS Forum of Neuroscience (rok: 2018, ), Wydawca: Federation of European Neuroscence Society
    Data:
    konferencja 7-11.07
    Status:
    Published