Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Assesment of the sensitization of the frequency-modulated 50kHz ultrasonic vocalization response to amphetamine as a predictor of susceptibility to addiction to this psychostimulant and a search for neurobiological foundation of the susceptibility

2015/19/B/NZ7/03610

Keywords:

ultrasonic vocalizations addiction amphetamine self-administration individual differences sensitization FosB immunohistochemistry,

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ4_12: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Psychiatrii i Neurologii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Ewa Taracha 

Number of co-investigators in the project: 6

Call: OPUS 10 - announced on 2015-09-15

Amount awarded: 1 110 404 PLN

Project start date (Y-m-d): 2016-07-20

Project end date (Y-m-d): 2021-07-19

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. 25 ft Shock Cable - 8 conductor okablowanie (15 680 PLN)
  2. Precision Animal Shocker (Manual) - stymulator elektryczny (124 642 PLN)
  3. Condenser ultrasound microphone - mikrofony (36 800 PLN)
  4. serwer synology.
  5. H03-04 Environment Connection Board (ECB) & linc cable tablica regulująca środowisko w klatce (10 960 PLN)
  6. LED House light rat światło tzw. domowe (11 942 PLN)
  7. Prog.Infusion Pump 0.02 - 2 RPM - pompy infuzyjne (87 920 PLN)
  8. Triple cue with LED - sygnalizacja świetlna stosowana podczas warunkowania (9 324 PLN)
  9. Coulbourn USB interface- interfejs (7 073 PLN)
  10. Graphic State Upgrade to Version 4 and computer- aktualizacja oprogramowania +komputer (19 556 PLN)
  11. 4,5 khz High Power Tone Module Rat.
  12. np. Avisoft-UltraSoundGate 416Hb, educational moduł do rejestracji USV (51 966 PLN)
  13. Habitest Linc (a full system may include from 1 to 8) H02-08 urządzenie przetwarzające (70 075 PLN)
  14. Nose Poke Operandum - Rat -otwór do zajrzeń wraz z czujnikami (38 164 PLN)
  15. np. Avisoft-SASLab Pro, educational price +komputer (14 242 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Diverging changes in rat striatal extracellular dopamine and DOPAC levels and in frequency-modulated 50-kHz ultrasonic vocalizations rate during repeated amphetamine treatment
    Authors:
    Magdalena Czarna, Karolina Kuchniak, Stanisław J Chrapusta, Danuta Turzyńska, Adam Płaźnik, Ewa Taracha
    Academic press:
    Behavioural Brain Research (rok: 2020, tom: 393, strony: 45300), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbr.2020.112745 - link to the publication
  2. The role of serotoninergic system in psychostimulant effects
    Authors:
    Ewa Taracha
    Academic press:
    Advances in Psychiatry and Neurology (rok: 2021, tom: 30, strony: 258-269), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.5114/ppn.2021.111939 - link to the publication
  3. Using anticipatory and drug-evoked appetitive ultrasonic vocalization for monitoring the rewarding effect of amphetamine in a rat model of drug self-administration.
    Authors:
    Kuchniak K, Wyszogrodzka E, Chrapusta SJ, Czarna M, Michalak M, Płaźnik A, Krząścik P, Mierzejewski P, Taracha E
    Academic press:
    Behav Brain Res (rok: 2019, tom: 376, strony: jeszcze nie podano), Wydawca: Elsevier Science B. V.
    Status:
    Published
    DOI:
    10.1016/j.bbr.2019.112187 - link to the publication
  4. Effects of amphetamine administration on neurogenesis in adult rats.
    Authors:
    Stępień T, Taracha E, Kaniuga E, Płaźnik A, Wierzba-Bobrowicz T.
    Academic press:
    Folia Neuropathol. 2017;55(4):333-339. doi: 10.5114/fn.2017.72396. (rok: 2017, tom: 55, strony: 333-339), Wydawca: Termedia
    Status:
    Published
    DOI:
    10.5114/fn.2017.72396. - link to the publication

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