DExD/H-box RNA helicases in fish anti-viral immune response

2015/18/E/NZ6/00516

Keywords

Descriptors

  • NZ6_1: Odporność swoista i nieswoista
  • NZ6_3: Immunologia zwierząt
  • NZ6_5: Wirusologia

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Jagielloński, Wydział Biologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Krzysztof Łukasz Rakus

Number of co-investigators in the project: 3

Call

SONATA BIS 5 – announced on 2015-06-15

Amount awarded
1 473 500 PLN
Project start date
2016-06-08
Project end date
2023-06-07
Project duration
84 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparatura do mikroiniekcji. Cost: 94 000 PLN
  2. Aparatura do mikroiniekcji: Mikroskop stereoskopowy.
  3. Aparatura do mikroiniekcji: reduktor butlowy.
  4. Inkubator CO2. Cost: 44 000 PLN
  5. Inkubator mikrobiologiczny.
  6. Komora laminarna klasy II. Cost: 56 500 PLN
  7. Wielodetekcyjny czytnik płytek. Cost: 85 000 PLN
  8. licencja na oprogramowanie Office Professional 2016 firmy Microsoft (1 sztuka).

Information in the final report

Publication in academic press/journals (10)

  1. Type I interferon-dependent response of zebrafish larvae during tilapia lake virus (TiLV) infection

    Authors:
    Widziolek M., Janik K., Mojzesz M., Pooranachandran N., Adamek M., Pecio A., Surachetpong W., Levraud J.-P., Boudinot P., Chadzinska M., Rakus K.
    Academic press:
    Developmental and Comparative Immunology (year: 2021, volume: 116, pages: 103936), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.dci.2020.103936 – link to the publication
  2. Type I interferon responses of common carp strains with different levels of resistance to koi herpesvirus disease during infection with CyHV-3 or SVCV

    Authors:
    Adamek M., Matras M., Dawson A., Piackova V., Gela D., Kocour M., Adamek J., Kaminski R., Rakus K., Bergmann S.M., Stachnik M., Reichert M., Steinhagen D.
    Academic press:
    Fish & Shellfish Immunology (year: 2019, volume: 87, pages: 809-819), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fsi.2019.02.022 – link to the publication
  3. Cytosolic sensors for pathogenic viral and bacterial nucleic acids in fish

    Authors:
    Mojzesz M., Rakus K., Chadzinska M., Nakagami K., Biswas G., Sakai M., Hikima J.
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 21, pages: E7289), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21197289 – link to the publication
  4. Jak infekcje i cytokiny wpływają na sen i zachowanie zwierząt?

    Authors:
    Rakus K., Chadzinska M
    Academic press:
    KOSMOS (year: 2020, volume: 69, pages: 461-473), Publisher: Polskie Towarzystwo Przyrodników im. Kopernika
    Status:
    Published
  5. Tilapia Lake Virus-Induced Neuroinflammation in Zebrafish: Microglia Activation and Sickness Behavior

    Authors:
    Mojzesz M., Widziolek M., Adamek M., Orzechowska U., Podlasz P., Prajsnar T.K., Pooranachandran N., Pecio A., Michalik A., Surachetpong W., Chadzinska M., Rakus K.
    Academic press:
    Frontiers in Immunology (year: 2021, volume: 12, pages: 760882), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2021.760882 – link to the publication
  6. Receptory rozpoznające wirusowe kwasy nukleinowe w odpowiedzi przeciwwirusowej ryb

    Authors:
    Krzysztof Rakus, Magdalena Chadzińska
    Academic press:
    Kosmos (year: 2017, volume: 66, pages: 609-621), Publisher: Polskie Towarzystwo Przyrodników im. Kopernika
    Status:
    Published
  7. Evaluation of zebrafish (Danio rerio) as an animal model for the viral infections of fish

    Authors:
    Rakus K., Adamek M., Mojżesz M., Podlasz P., Chmielewska-Krzesińska M., Naumowicz K., Kasica-Jarosz N., Kłak K., Rakers S., Way K., Steinhagen D., Chadzińska M
    Academic press:
    Journal of Fish Diseases (year: 2019, volume: 42, pages: 923-934), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/jfd.12994 – link to the publication
  8. Acyclovir inhibits Cyprinid herpesvirus 3 multiplication in vitro.

    Authors:
    Troszok A., Kolek L., Szczygieł J., Wawrzeczko J., Borzym E., Reichert M., Kamińska T., Ostrowski T., Jurecka P., Adamek M., Rakus K., Irnazarow I.
    Academic press:
    Journal of Fish Diseases (year: 2018, volume: 41, pages: 1709-1718), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/jfd.12880 – link to the publication
  9. Antiviral response of adult zebrafish (Danio rerio) during tilapia lake virus (TiLV) infection

    Authors:
    Rakus K., Mojzesz M., Widziolek M., Pooranachandran N., Teitge F., Surachetpong W., Chadzinska M., Steinhagen D., Adamek M.
    Academic press:
    Fish and Shellfish Immunology (year: 2020, volume: 101, pages: 46030), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fsi.2020.03.040 – link to the publication
  10. Viral infection-induced changes in the expression profile of non-RLR DExD/H-box RNA helicases (DDX1, DDX3, DHX9, DDX21 and DHX36) in zebrafish and common carp

    Authors:
    Mojzesz M., Klak K., Wojtal P., Adamek M., Podlasz P., Chmielewska-Krzesinska M., Matras M., Reichert M., Chadzinska M., Rakus K.
    Academic press:
    Fish and Shellfish Immunology (year: 2020, volume: 104, pages: 62-73), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fsi.2020.06.010 – link to the publication

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Graphic design and implementation: Jakub Piotrowski