Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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New analytical solutions in oncology: from basic research to rapid intraoperative diagnostics

2015/18/M/ST4/00059

Keywords:

solid phase microextraction metabolomics biomarkers cancer oncology brain tumor meningioma glioma imaging real time analysis

Descriptors:

  • ST4_6: Instrumental methods in chemistry
  • NZ5_5: Diagnostics in human diseases
  • NZ5_1: Etiology of human diseases

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Mikołaja Kopernika, Collegium Medicum im. Ludwika Rydygiera w Bydgoszczy, Wydział Farmaceutyczny

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Barbara Bojko 

Number of co-investigators in the project: 12

Call: HARMONIA 7 - announced on 2015-06-15

Amount awarded: 621 960 PLN

Project start date (Y-m-d): 2016-04-13

Project end date (Y-m-d): 2020-04-12

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (15)
  1. A new strategy for brain tumour metabolomic analysis
    Authors:
    Paulina Zofia Goryńska, Kamila Chmara, Krzysztof Goryński, Dariusz Paczkowski, Marek Harat, Barbara Bojko
    Academic press:
    Medical Research Journal 2018 (rok: 2018, tom: 3, strony: 45299), Wydawca: Via Medica
    Status:
    Published
    DOI:
    10.5603/MRJ.2018.000 - link to the publication
  2. Coated Blade Spray-Mass Spectrometry as a New Approach for the Rapid Characterization of Brain Tumors
    Authors:
    Joanna Bogusiewicz, Magdalena Gaca-Tabaszewska, Dominik Olszówka, Karol Jaroch, Jacek Furtak, Marek Harat, Janusz Pawliszyn, Barbara Bojko
    Academic press:
    Molecules (rok: 2022, tom: 27, strony: 2251), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules27072251 - link to the publication
  3. Investigating the Potential Use of Chemical Biopsy Devices to Characterize Brain Tumor Lipidomes
    Authors:
    Joanna Bogusiewicz 1 , Bogumiła Kupcewicz 2 , Paulina Zofia Goryńska, Karol Jaroch, Krzysztof Goryński, Marcin Birski, Jacek Furtak, Dariusz Paczkowski, Marek Harat, Barbara Bojko
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 3518), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  4. Metabolomic Phenotyping of Gliomas: What Can We Get with Simplified Protocol for Intact Tissue Analysis?
    Authors:
    Paulina Zofia Goryńska, Kamila Chmara, Bogumiła Kupcewicz, Krzysztof Goryński, Karol Jaroch, Dariusz Paczkowski, Jacek Furtak, Marek Harat, Barbara Bojko
    Academic press:
    Cancers (rok: 2022, tom: 14, strony: 312), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers14020312 - link to the publication
  5. On-Site Sampling and Extraction of Brain Tumors for Metabolomics and Lipidomics Analysis
    Authors:
    Joanna Bogusiewicz, Paulina Zofia Goryńska, Magdalena Gaca, Kamila Chmara, Krzysztof Goryński, Karol Jaroch, Dariusz Paczkowski, Jacek Furtak, Marek Harat, Barbara Bojko
    Academic press:
    JoVE - Journal of Visualized Experiments (rok: 2020, tom: 159, strony: e61260), Wydawca: MyJove Corp.
    Status:
    Published
    DOI:
    10.3791/61260 - link to the publication
  6. Profiling of Carnitine Shuttle System Intermediates in Gliomas Using Solid-Phase Microextraction (SPME)
    Authors:
    Joanna Bogusiewicz, Katarzyna Burlikowska, Karol Jaroch, Paulina Zofia Goryńska, Krzysztof Goryński, Marcin Birski, Jacek Furtak, Dariusz Paczkowski, Marek Harat, Barbara Bojko
    Academic press:
    Molecules (rok: 2021, tom: 26, strony: 6112), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules26206112 - link to the publication
  7. SPME in clinical, pharmaceutical, and biotechnological research – how far are we from daily practice?
    Authors:
    Wojciech Filipiak, Barbara Bojko
    Academic press:
    Trends in Analytical Chemistry (rok: 2019, tom: 115, strony: 203-213), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.trac.2019.02.029 - link to the publication
  1. Genetic landscape of meningiomas and its implication to lipidome composition
    Authors:
    Bogusiewicz J., Gaca-Tabaszewska M., Modrakowska P., Soszyńska K., Majdańska A., Ryfa A., Jaroch K., Goryńska P.Z., Goryński K., Birski M., Furtak J., Harat M., Paczkowski D., Bojko B.
    Conference:
    4th Central European Biomedical Congress (rok: 2021, ), Wydawca: Agencja Reklamowa EURO GRAPHIC
    Data:
    konferencja 07-09.06.2021
    Status:
    Published
  2. LIPIDOMICS IN HISTOLOGICAL AND GENETIC DIFFERENTIATION OF BRAIN TUMORS
    Authors:
    Bogusiewicz J., Goryńska P.Z., Jaroch K., Goryński K., Paczkowski D., Furtak J., Harat M., Bojko B.
    Conference:
    6 SCIENTIFIC CONFERENCE Metabolomics Circle 2019 (rok: 2019, ), Wydawca: Institute of Animal Reproduction and Food Research, Polish Academy of Sciences
    Data:
    konferencja 15-16.11
    Status:
    Published
  3. Application of Coated Blade Spray Mass Spectrometry in Lipidomic Analysis
    Authors:
    oanna Bogusiewicz Dominik Olszówka, Karol Jaroch, Paulina Zofia Gorynska, Krzysztof Gorynski, Marcin Birski, Jacek Furtak, Dariusz Paczkowski, Marek Harat, Barbara Bojko
    Conference:
    9th International Singapore Lipid Symposium (rok: 2021, ), Wydawca: National University of Singapore
    Data:
    konferencja 01.03-05.03.2021
    Status:
    Published
  4. Brain tumor metabolite analysis using non-invasive method SPME and platform LC-MS. Introduction research
    Authors:
    Kamila Chmara, Paulina Zofia Goryńska, Krzysztof Goryński, Karol Jaroch, Dariusz Paczkowski, Marek Harat, Barbara Bojko
    Conference:
    2nd International MEDical Interdisciplinary Congress 2017 Bydgoszcz (rok: 2017, ), Wydawca: Uniwersytet Mikołaja Kopernika
    Data:
    konferencja 10,06
    Status:
    Published
  5. Chemical Biopsy as an Alternative Sampling Method in Neurooncology
    Authors:
    J Bogusiewicz, P Z Goryńska, K Jaroch, K Goryński, D Paczkowski, J Furtak, M Harat, B Bojko
    Conference:
    14th Meeting of the European Association of Neuro-Oncology (rok: 2019, ), Wydawca: Oxford University Press
    Data:
    konferencja 19-22.09
    Status:
    Published
  6. Multidirectional Differential Metabolomic Analysis of Selected Brain Tumors in Humans
    Authors:
    P.Z. Goryńska, K. Goryński, K. Chmara, K. Jaroch, D. Paczkowski, J.Furtak, M. Harat, B.Kupcewicz, B. Bojko
    Conference:
    MSACL EU 2018 (Mass Spectrometry: Applications to the Clinical Lab) (rok: 2018, ), Wydawca: The Association of Mass Spectrometry: Applications to the Clinical Lab
    Data:
    konferencja 9-13.09.2018
    Status:
    Published
  7. Solid phase micro extraction for brain tumor metabolite analysis
    Authors:
    P.Z.Goryńska, K. Goryński, K. Chmara, K. Jaroch, D. Paczkowski, M. Harat, B. Bojko
    Conference:
    45th international Symposium on High Performance Liquid Phase Separations and Related Techniques (rok: 2017, ), Wydawca: WWW.HPLC2017-PRAGUE.ORG
    Data:
    konferencja 18-22.06.2017
    Status:
    Published
  8. PROFILING OF CARNITINE AND ACYLCARNITINES IN GLIOMAS USING SOLID PHASE MICROEXTRACTION (SPME) –THE PILOT STUDY
    Authors:
    Joanna Bogusiewicz, Katarzyna Burlikowska, Karol Jaroch, Paulina Zofia Gorynska, Krzysztof Gorynski, Marcin Birski, Jacek Furtak, Dariusz Paczkowski, Marek Harat, Barbara Bojko
    Conference:
    23rd International Symposium on Advances in Extraction Technologies (rok: 2021, ), Wydawca: Universidad de Alicante
    Data:
    konferencja 30.06.-02.07.2021
    Status:
    Published
  9. Assessment of the lipidome of brain tumors extracted using Solid Phase Microextraction (SPME) directly after tumor resection and after freezing
    Authors:
    Magdalena Gaca-Tabaszewska, Joanna Bogusiewicz, Bogumiła Kupcewicz, Paulina Zofia Goryńska, Karol Jaroch, Krzysztof Goryński, Jacek Furtak, Dariusz Paczkowski, Marcin Birski, Marek Harat, Barbara Bojko
    Conference:
    9th International Singapore Lipid Symposium (rok: 2021, ), Wydawca: National University of Singapore
    Data:
    konferencja 01.03-05.03.2021
    Status:
    Published
  10. Lipidomic analysis of brain tumor by solid phase microextraction
    Authors:
    Joanna Bogusiewicz, Paulina Zofia Goryńska, Krzysztof Goryński, Karol Jaroch, Dariusz Paczkowski, Marcin Birski, Jacek Furtak, Marek Harat, Barbara Bojko
    Conference:
    21st International Symposium on Advances in Extraction Technologies (rok: 2019, ), Wydawca: Sun Yet-sen University
    Data:
    konferencja 09-13.11.2019
    Status:
    Published
  11. SPME-BASED SAMPLE PREPARATION STRATEGIES IN CLINICAL AND BIOMEDICAL ANALYSIS
    Authors:
    Anna Roszkowska, Joanna Bogusiewicz, Paulina Zofia Goryńska, Kamil Łuczykowski, Katarzyna Burlikowska, Karol Jaroch, Krzysztof Goryński, Marcin Birski, Dariusz Paczkowski, Jacek Furtak, Marek Harat, Tomasz Bączek, Janusz Pawliszyn, Barbara Bojko
    Conference:
    23rd International Symposium on Advances in Extraction Technologies (rok: 2021, ), Wydawca: Universidad de Alicante
    Data:
    konferencja 30.06.-02.07.2021
    Status:
    Published
  12. Solid Phase Microextraction – High Resolution Mass Spectrometry: Integrated Platform for Multilevel Clinical Analysis
    Authors:
    Paulina Goryńska, Krzysztof Goryński, Iga Stryjak, Nathaly Reyes-Garces, German Gomez-Rios, Janusz Pawliszyn, Barbara Bojko
    Conference:
    MSACL US 2017 (Mass Spectrometry Application to the Clinical Lab) (rok: 2017, ), Wydawca: The Association for Mass Spectrometry Application to the Clinical Lab
    Data:
    konferencja 22.01.2-17-26.01.2017
    Status:
    Published
    DOI:
    link to the publication
  13. Application of solid phase microextraction to in vivo brain and brain tumor analysis
    Authors:
    Joanna Bogusiewicz, Paulina Zofia Goryńska, Kamil Łuczykowski, Katarzyna Burlikowska, Karol Jaroch, Kamila Chmara, Krzysztof Goryński, Dariusz Paczkowski, Jacek Furtak, Marek Harat, Janusz Pawliszyn, Barbara Bojko
    Conference:
    XX Euroanalysis (rok: 2019, ), Wydawca: EUROANALYSIS
    Data:
    konferencja 01-05.10
    Status:
    Published
  14. Ocena lipidom guzów mózgu ekstrahowanego z wykorzystaniem biopsji chemicznej bezpośrednio po wycięciu guza i po mrożeniu
    Authors:
    Magdalena Gaca-Tabaszewska, Joanna Bogusiewicz, Paulina Zofia Goryńska, Karol Jaroch, Krzysztof Goryński, Jacek Furtak, Dariusz Paczkowski, Marcin Birski, Marek Harat, Barbara Bojko
    Conference:
    Ogólnopolska Konferencja Młodych Naukowców nt. Nowe Trendy w Badanaich Naukowych (rok: 2021, ), Wydawca: Creativetime
    Data:
    konferencja 26-28.02.2021
    Status:
    Published
  15. THE USE OF MICROEXTRACTION TO THE SOLID PHASE IN LIPIDOMICS OF BRAIN TUMORS
    Authors:
    J. Bogusiewicz, M. Gaca, P. Goryńska, K. Jaroch, K. Goryński, B. Bojko
    Conference:
    Metabolomics Circle (rok: 2018, ), Wydawca: UMK
    Data:
    konferencja 26-28.10.2018
    Status:
    Published

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