Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Possible significance of blood platelet COX-1 glycation and ubiquitination in understaniding of the molecular background of 'aspirin resistance' in patients with type 2 diabetes.

2015/17/N/NZ5/02605

Keywords:

non-enzymatic glycation COX-1 protein ubiquitination aspirin resistance blood platelet activation diabetes

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ5_3: Pathogenesis of human diseases
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Uniwersytet Medyczny w Łodzi

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Hassan Kassassir 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 95 510 PLN

Project start date (Y-m-d): 2016-03-15

Project end date (Y-m-d): 2019-03-14

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (1)
  • Articles in post-conference publications (2)
  1. Non-enzymatic modifications of prostaglandin H synthase 1 affect bifunctional enzyme activity - Implications for the sensitivity of blood platelets to acetylsalicylic acid.
    Authors:
    Hassan Kassassir, Karolina Siewiera, Marcin Talar, Emilia Stec-Martyna, Zofia Pawlowska, Cezary Watala
    Academic press:
    Chemico-Biological Interactions (rok: 2016, tom: 253, strony: 78-92), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cbi.2016.04.021 - link to the publication
  1. Parameters of blood morphology and platelet activation undergo changes during streptozotocin-induced diabetes in rats.
    Authors:
    Karolina Siewiera, Hassan Kassassir, Tomasz Przygodzki, Dawid Polak, Nina Wolska, Marcin Talar, Cezary Watala
    Conference:
    25th Kraków Conference on Endothelium (rok: 2017, ), Wydawca: Jagiellonian Centre for Experimental Therapeutics
    Data:
    konferencja 20-21 października 2017 roku
    Status:
    Published
  2. Prostaglandin H synthase 1 undergoes non-enzymatic N-glycosylation in platelets fromdiabetic rats
    Authors:
    Hassan Kassassir, Karolina Siewiera, Emilia Stec-Martyna, Zofia Pawlowska, Cezary Watala
    Conference:
    1st Italian-UK Platelet Meeting University of Bath (rok: 2017, ), Wydawca: Platelets
    Data:
    konferencja 7-8 września 2017 roku
    Status:
    Published

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy