Changes in the functioning of mitochondria as a potential factor promoting the procoagulant activity of blood platelets in diabetes

2015/17/N/NZ5/02603

Keywords

Descriptors

  • NZ5_1: Etiologia chorób człowieka
  • NZ5_3: Patogeneza chorób człowieka
  • NZ5_7: Leczenie chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Uniwersytet Medyczny w Łodzi, Wydział Nauk o Zdrowiu

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Karolina Małgorzata Siewiera

Number of co-investigators in the project: 2

Call

PRELUDIUM 9 – announced on 2015-03-16

Amount awarded
99 600 PLN
Project start date
2016-03-15
Project end date
2019-03-14
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (1)

  1. Sample Preparation as a Critical Aspect of Blood Platelet Mitochondrial Respiration Measurements-The Impact of Platelet Activation on Mitochondrial Respiration.

    Authors:
    Siewiera, K.; Labieniec-Watala, M.; Wolska, N.; Kassassir, H.; Watala, C.
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: n/a (wydanie online)), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22179332 – link to the publication

Articles in post-conference publications (5)

  1. Changes in blood platelet and brain mitochondrial respiration during short and longlasting STZ-induced diabetes

    Authors:
    Siewiera K, Labieniec-Watala M, Karolczak K,Wolska N, Polak D, Kassassir H, Watala C
    Conference:
    12th Conference on Mitochondrial Physiology The role of mitochondria in lifestyle and metabolic syndrome (year: 2017, pages: wersja online), Publisher: Mitochondrial Physiology Society (2017-11-15) MitoGlobal
    Date:
    conference 15-18 listopada 2017
    Status:
    Published
    DOI:
    link to the publication
  2. Parameters of blood morphology and platelet activation undergo changes during streptozotocin-induced diabetes in rats.

    Authors:
    Karolina Siewiera, Hassan Kassassir, Tomasz Przygodzki, Dawid Polak, Nina Wolska, Marcin Talar, Cezary Watala
    Conference:
    25th Kraków Conference on Endothelium (year: 2017, pages: 1-118), Publisher: Jagiellonian Centre for Experimental Therapeutics
    Date:
    conference 20-21 października 2017 roku
    Status:
    Published
  3. The effect of metformin on blood platelet bioenergetics and platelet function.

    Authors:
    Siewiera K, Hertel J, Labieniec-Watala M, Kassassir H, Watala C
    Conference:
    Mitochondrial fitness mapping: Conference, Working Groups and MC meeting - COST Action MITOEAGLE (year: 2017, pages: jeszcze nieznane), Publisher: Bioblast, MITOEAGLE
    Date:
    conference 21-23 marzec 2017
    Status:
    Published
    DOI:
    link to the publication
  4. Blood platelets as bioenergetic markers of brain damage in STZ-diabetes

    Authors:
    Siewiera K, Labieniec-Watala M, Wolska N, Polak D, Kassassir H, Watala C
    Conference:
    10th MiPschool 2017 (year: 2017, pages: wydane online), Publisher: Bioblast, MITOEAGLE
    Date:
    conference 23-30 lipca 2017
    Status:
    Published
    DOI:
    link to the publication
  5. Altered blood platelet reactivity is not related to elevated mitochondrial respiration in rat model of streptozotocin-induced diabetes

    Authors:
    Karolina Siewiera, Magdalena Labieniec-Watala, Hassan Kassassir, Dawid Polak, Nina Wolska, Cezary Watala
    Conference:
    1st Italian-UK Platelet Meeting University of Bath (year: 2017, pages: 747), Publisher: Platelets
    Date:
    conference 7-8 września 2017 roku
    Status:
    Published

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