Recognition of genes associated with H3K4me3 histone protein responsible for polarization of neutrophils into suppressor cells during refractory inflammatory diseases
2015/17/B/NZ6/04251
Keywords
Descriptors
- NZ6_1: Odporność swoista i nieswoista
- NZ6_2: Immunologia kliniczna
- NZ3_3: Apoptoza
Panel
NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution
Uniwersytet Medyczny w Łodzi, Wydział Lekarski
Voivodeship: łódzkie
Principal investigator (from the host institution)
dr hab. Przemysław Andrzej Lewkowicz
Number of co-investigators in the project: 6
Call
OPUS 9 – announced on 2015-03-16
- Amount awarded
- 1 018 800 PLN
- Project start date
- 2016-03-01
- Project end date
- 2021-02-28
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Aparat do dezitegracji chromatyny - Bioruptor pico firmy DIAGENODE.
- aprat do elktroforezy białek wraz z zasilaczem i systemen do transferu (western blot). Cost: 30 000 PLN
Information in the final report
Publication in academic press/journals (3)
-
C5a-Preactivated Neutrophils Are Critical for Autoimmune-Induced Astrocyte Dysregulation in Neuromyelitis Optica Spectrum Disorder.
- Authors:
- Piatek P, Domowicz M, Lewkowicz N, Przygodzka P, Matysiak M, Dzitko K and Lewkowicz P.
- Academic press:
- Frontiers in Immunology (year: 2018, volume: volume 9, pages: 1694-1710), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fimmu.2018.01694 – link to the publication
-
H3K4me3 histone ChIPseq Analysis Reveals Molecular Mechanisms Responsible for Neutrophil dysfunction in HIV-infected individuals
- Authors:
- Paweł Piatek, Maciej Tarkowski, Magdalena Namiecinska, Agostino Riva, Marek Wieczorek, Sylwia Michlewska, Justyna Dulska, Małgorzata Domowicz, Małgorzata Kulińska-Michalska, Natalia Lewkowicz and Przemysław Lewkowicz
- Academic press:
- Frontiers in Immunology (year: 2021, volume: VOL 12: 682094, pages: 2021 Jul 15;12:682094), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fimmu.2021.682094 – link to the publication
-
Changes within H3K4me3-marked histone reveal molecular background of neutrophil functional plasticity
- Authors:
- Paweł Piatek, Magdalena Namiecinska, Natalia Lewkowicz, Małgorzata Kulińska-Michalska, Zbigniew Jabłonowski, Mariola Matysiak, Justyna Dulska, Sylwia Michlewska, Marek Wieczorek, and Przemysław Lewkowicz
- Academic press:
- Frontiers in Immunology (year: 2022, volume: Vol.13 June 2022 Article 906311, pages: Article 906311 1-20), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fimmu.2022.906311 – link to the publication