Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Multifunctional hybrid organic-inorganic particles for theranostic applications

2015/17/N/ST4/03926

Keywords:

doxorubicin gold nanoparticles PEG PLGA sulforaphane theranostic Au-198 radioisotope.

Descriptors:

  • ST4_2: Spectroscopic and spectrometric techniques
  • ST5_15:

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Chemii

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Paulina Głowala 

Number of co-investigators in the project: 3

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 149 998 PLN

Project start date (Y-m-d): 2016-02-22

Project end date (Y-m-d): 2019-02-21

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw komputerowy z drukarką (5 104 PLN)
  2. Radiometr uniwersalny (3 936 PLN)
  3. Uniwersalny czytnik mikropłytkowy (31 000 PLN)
  4. Mineralizator.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (2)
  1. Sulforaphane-conjugated selenium nanoparticles: towards a synergistic anticancer effect
    Authors:
    Krug, P. Mielczarek, L. Wiktorska, K. Kaczyńska, K. Wojciechowski, P. Andrzejewski, K. Ofiara, K. Szterk, A. Mazur, M.
    Academic press:
    Nanotechnology (rok: 2019, tom: 30, strony: 65101), Wydawca: IOP Publishing
    Status:
    Published
    DOI:
    10.1088/1361-6528/aaf150 - link to the publication
  2. In the triple-negative breast cancer MDA-MB-231 cell line, sulforaphane enhances the intracellular accumulation and anticancer action of doxorubicin encapsulated in liposomes
    Authors:
    Mielczarek, L. Krug, P. Mazur, M. Milczarek, M. Chilmonczyk, Z. Wiktorska, K.
    Academic press:
    International Journal of Pharmaceutics (rok: 2019, tom: 558, strony: 311-318), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.ijpharm.2019.01.008 - link to the publication
  3. Magnetic polymer microcapsules loaded with Nile Red fluorescent dye
    Authors:
    Bartel, M. Wysocka, B. Krug, P. Kepinska, D. Kijewska, K. Blanchard, G. J. Kaczynska, K. Lubelska, K. Wiktorska, K. Glowala, P. Wilczek, M. Pisarek, M. Szczytko, J. Twardowski, A. Mazur, M.
    Academic press:
    Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy (rok: 2018, tom: 195, strony: 148-156), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.saa.2018.01.056 - link to the publication
  4. Polypyrrole microcapsules loaded with gold nanoparticles: Perspectives for biomedical imaging
    Authors:
    Krug, P. Kwiatkowska, M. Mojzych, I. Głowala, P. Dorant, S. Kępińska, D. Chotkowski, M. Janiszewska, K. Stolarski, J. Wiktorska, K. Kaczyńska, K. Mazur, M.
    Academic press:
    Synthetic Metals (rok: 2019, tom: 248, strony: 27-34), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.synthmet.2018.12.025 - link to the publication
  5. Nano-radiogold-decorated composite bioparticles
    Authors:
    Wójtowicz, A. Krug, P. Głowala, P. Hungria, A. B. Chotkowski, M. Wiktorska, K. Mazur, M.
    Academic press:
    Materials Science & Engineering C-Materials for Biological Applications (rok: 2019, tom: 97, strony: 768-775), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.msec.2018.12.085 - link to the publication
  1. Hybrid colloidal particles
    Authors:
    Maciej Mazur, Paulina Głowala, Marta Bartel, Barbara Wysocka, Pamela Krug, Marta Kwiatkowska, Ilona Mojzych, Jarosław Wojciechowski
    Conference:
    XIVth International Conference on Molecular Spectroscopy (rok: 2017, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 03-07.09.2017
    Status:
    Published
  2. PLGA microspheres modified with gold-198 radioisotope - polymer carriers of anticancer drug doxorubicin
    Authors:
    Paulina Głowala, Krystyna Kijewska, Gary J. Blanchard, Maciej Mazur
    Conference:
    The 68th Annual Meeting of the International Society of Electrochemistry (rok: 2017, ), Wydawca: International Society of Electrochemistry
    Data:
    konferencja 27.08-01.09.2017
    Status:
    Published
    DOI:
    link to the publication

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