Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The influence of neighbouring group participation and nuclephilicity of amino groups on the course of three-component condensation of diamines with triethyl orthoformate and diethyl phosphite

2015/17/N/ST5/02006

Keywords:

bisphosphonates multi-component reaction reaction mechanism osteoporosis

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Politechnika Wrocławska

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Patrycja Petruczynik 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 100 000 PLN

Project start date (Y-m-d): 2016-03-16

Project end date (Y-m-d): 2018-03-15

Project duration:: 24 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Kriostat (24 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Reaction of 3-Amino-1,2,4-Triazole with Diethyl Phosphite and Triethyl Orthoformate: Acid-Base Properties and Antiosteoporotic Activities of the Products
    Authors:
    Patrycja Miszczyk, Dorota Wieczorek, Joanna Gałęzowska, Błażej Dziuk, Joanna Wietrzyk, Ewa Chmielewska
    Academic press:
    Molecules (rok: 2017, tom: 22(2), strony: 254), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules22020254 - link to the publication
  2. Three-component reaction of benzylamines, diethyl phosphite and triethyl orthoformate: dependence of the reaction course on the structural features of the substrates and reaction conditions
    Authors:
    Miszczyk Patrycja, Turowska-Tyrk Ilona, Kafarski Paweł, Chmielewska Ewa
    Academic press:
    Molecules (rok: 2017, tom: 22(3), strony: 450), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules22030450 - link to the publication

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