Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Studies on Stereoselective Kinugasa Reaction

2015/17/B/ST5/01011

Keywords:

Kinugasa reaction stereoselective reactions beta-lactam compounds antibiotics

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Chemii Organicznej PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Marek Chmielewski 

Number of co-investigators in the project: 4

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 803 120 PLN

Project start date (Y-m-d): 2016-03-16

Project end date (Y-m-d): 2020-03-15

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Linia Schlenka (azotowo-próżniowa) (2 szt.) (10 000 PLN)
  2. oprogramowanie D2000 (1 225 PLN)
  3. Agregat chłodzący (2 szt.) (25 000 PLN)
  4. Instalacja do gazów laboratoryjnych (15 000 PLN)
  5. Komputer wraz z monitorem i oprogramowaniem (5 000 PLN)
  6. Pompa próżniowa olejowa (8 000 PLN)
  7. Wyparka próżniowa wraz z pompą i kontrolerem próżni (35 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Bypassing the stereoselectivity issue: transformations of Kinugasa adducts from chiral alkynes and non-chiral acyclic nitrones
    Authors:
    Rafał Kutaszewicz, Barbara Grzeszczyk, Marcin Górecki, Olga Staszewska-Krajewska, Bartłomiej Furman, Marek Chmielewski
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2019, tom: 17, strony: 6251-6268), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C9OB00940J - link to the publication
  2. Synthesis of Monobactams via the Diastereoselective Kinugasa Reaction
    Authors:
    Kabala, K.; Grzeszczyk, B .; Furman, B .; Chmielewski, M .; Solecka, J.; Guspiel, A.
    Academic press:
    Synthesis (rok: 2018, tom: 50, strony: 1991-2000), Wydawca: Thieme
    Status:
    Published
    DOI:
    10.1055/s-0037-1609304 - link to the publication
  3. Synthesis of β-lactams via diastereoselective, intramolecular Kinugasa reactions
    Authors:
    Oskar Popik, Barbara Grzeszczyk, Olga Staszewska-Krajewska, Bartłomiej Furman, Marek Chmielewski
    Academic press:
    Organic & Biomolecular Chemistry (rok: 2020, tom: 18, strony: 2852-2860), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D0OB00228C - link to the publication