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Information of the project and the call

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The involvement of peroxisome proliferator-activated receptors (PPARs) in the regulation of cytokines synthesis in porcine endometrium

2015/17/B/NZ9/03596

Keywords:

PPARs pregnancy implantation inflammation nuclear receptors cytokines

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Warmińsko-Mazurski w Olsztynie, Wydział Biologii i Biotechnologii

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Iwona Bogacka 

Number of co-investigators in the project: 4

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 762 912 PLN

Project start date (Y-m-d): 2016-01-25

Project end date (Y-m-d): 2019-12-24

Project duration:: 47 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (9)
  1. PPARb/d ligands regulate the expression of immune response mediators in the porcine endometrium - an in vitro study
    Authors:
    Zuzanna Kunicka, Aleksandra Kurzyńska, Anna Szydłowska, Beata Kaczyńska, Iwona Bogacka
    Academic press:
    Theriogenology (rok: 2019, tom: 134, strony: 112-120), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.theriogenology.2019.05.022 - link to the publication
  2. Peroxisome proliferator-activated receptor alpha regulates the expression of the immune response mediators in the porcine endometrium during the estrous cycle and early pregnancy
    Authors:
    Zuzanna Kunicka Aleksandra Kurzyńska, Anna Szydłowska, Iwona Bogacka
    Academic press:
    Am J Reprod Immunol (rok: 2019, tom: 83(3):e13211, strony: 45301), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/aji.13211 - link to the publication
  3. Peroxisome proliferator-activated receptor gamma ligands affect NF-kB and cytokine synthesis in the porcine endometrium - An in vitro study.
    Authors:
    Kunicka Z, Kurzyńska A, Szydłowska A, Mierzejewski K, Bogacka I
    Academic press:
    Am J Reprod Immunol (rok: 2018, tom: 81(1):e13053, strony: 45301), Wydawca: John Wiley & Sons Ltd.
    Status:
    Published
    DOI:
    10.1111/aji.13053 - link to the publication
  4. Transcriptome analysis of porcine endometrium after LPS-induced inflammation: effects of the PPAR-gamma ligands in vitro
    Authors:
    Mierzejewski K, Paukszto Ł, Kurzyńska A, Kunicka Z, Jastrzębski JP, Bogacka I.
    Academic press:
    Biology of Reproductiom (rok: 2021, tom: 104 (1), strony: 130-143), Wydawca: Oxford academik
    Status:
    Published
    DOI:
    10.1093/biolre/ioaa200 - link to the publication
  1. Impact of peroxisome proliferator˗activated receptor (PPAR) ligands on pro-inflammatory cytokines synthesis in the porcine endometrium on days 10-12 of pregnancy or the estrous cycle (poster)
    Authors:
    Kurzynska A, Kaczynska B, Szydlowska A, Kilijanczyk M, Bogacka I
    Conference:
    Epiconcept, Epigenetics and Periconception Environment, Giardini Naxos, Włochy (rok: 2016, ), Wydawca: European Cooperation in Science and Technology
    Data:
    konferencja 26-29 września
    Status:
    Published
    DOI:
    link to the publication
  2. The effect of peroxisome proliferator-activated receptor (PPAR) ligands on the mRNA expression of Toll-like receptor (TLR-4) and anti-inflammatory cytokines (LIF and IL-10) in porcine endometrium on days 10-12 ofpregnancy and the estrous cycle.
    Authors:
    Kunicka Z., KurzyńskaA., Kaczyńska B., Szydłowska A., Grzankowska M., Bogacka I.
    Conference:
    VIII Zjazd Towarzystwa Biologii Rozrodu (rok: 2017, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 7-9 września
    Status:
    Published
    DOI:
    link to the publication
  3. The impact of peroxisome proliferator-activated receptor ligands on the expression of IL-1β and IL-6 in LPS-treated porcine endometrium during the estrous cycle
    Authors:
    Bogacka I., Kunicka Z., Szydłowska A., Kurzyńska A
    Conference:
    The extracellular vesicles paradigm of intra and intercellular communication (rok: 2019, ), Wydawca: European Cooperation in Science and Technology
    Data:
    konferencja 10-12 październik
    Status:
    Published
  4. Alternative splicing in the transcriptome of the porcine LPS-stimulated endometrium treated with PPAR? ligands during the mid-luteal phase of the estrous cycle
    Authors:
    Mierzejewski Karol, Paukszto Łukasz, Jastrzębski Jan P., Szydłowska Anna, Kurzyńska Aleksandra, Bogacka Iwona
    Conference:
    3D3C : toward new vista of in-vitro 3-dimensional organization and cell 2 cell communication : proceedings of the 3rd CellFit Workshop (rok: 2020, ), Wydawca: The Hebrew University
    Data:
    konferencja 03-06.03
    Status:
    Published
  5. Peroxisome proliferator-activated receptor ligands affect the expression of IL-1β and IL-6 in the porcine endometrium on days 18-20 of the estrous cycle
    Authors:
    Kunicka Z., Kurzyńska A., Szydłowska A., Kaczyńska B., Rosińska W., Golubska M., Bogacka I.
    Conference:
    The 5th Winter Workshop of the Society for Biology of Reproduction (rok: 2019, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 13-15 luty
    Status:
    Published
  6. Peroxisome proliferator-activated receptors (PPARs) participate in the synthesis of nuclear factor kappa-B (NF-kB) in porcine endometrium on days10-12 of pregnancy and the strous cycle.
    Authors:
    Kurzyńska A., Kunicka Z., Mierzejewski K., Siejwa P., Bogacka I.
    Conference:
    VIII Zjazd Towarzystwa Biologii Rozrodu (rok: 2017, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 7-9 września
    Status:
    Published
    DOI:
    link to the publication
  7. The effect of PPAR ligands on the expression of LIF and IL-10 in porcine endometrium during follicular phase of the estrous cycle
    Authors:
    Szydłowska A., Kurzyńska A., Kunicka Z., Mierzejewski K., Adamowicz J., Bogacka I.
    Conference:
    The 5th Winter Workshop of the Society for Biology of Reproduction (rok: 2019, ), Wydawca: Towarzystwo Biologii Rozrodu
    Data:
    konferencja 13-15 luty
    Status:
    Published
  8. The effect of PPAR gamma ligands on the transcriptome profile of LPS-treated porcine endometrium during mid-luteal phase of the estrous cycle
    Authors:
    Bogacka Iwona, Paukszto Łukasz, Kunicka Zuzanna, Mierzejewski Karol, Jastrzębski Jan P., Szydłowska Anna, Kurzyńska Aleksandra
    Conference:
    3D3C : toward new vista of in-vitro 3-dimensional organization and cell 2 cell communication : proceedings of the 3rd CellFit Workshop (rok: 2020, ), Wydawca: The Hebrew University
    Data:
    konferencja 03-06.03
    Status:
    Published
  9. The effect of PPAR ligands on the expression of LIF and IL-10 in porcine endometrium treated with LPS during the luteal phase of the estrous cycle
    Authors:
    Szydłowska A., Kunicka Z., Kurzyńska A., Bogacka I.
    Conference:
    The Extracellular Vesicles Paradigm of Intra and Intercellular Communication (rok: 2019, ), Wydawca: European Cooperation in Science and Technology
    Data:
    konferencja 10-12 październik
    Status:
    Published

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