Imaging miRNA biogenesis pathway and cellular localization of RNA interference triggers

2015/17/N/NZ3/03629

Keywords

Descriptors

  • NZ3_1: Biologia komórki
  • NZ1_1: Biologia molekularna
  • NZ3_2: Fizjologia komórki

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Martyna Olga Urbanek-Trzeciak

Number of co-investigators in the project: 2

Call

PRELUDIUM 9 – announced on 2015-03-16

Amount awarded
148 800 PLN
Project start date
2016-03-09
Project end date
2019-12-08
Project duration
45 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Obiektyw 100x klasy plan fluorytowej do jasnego pola oraz kontrastu fazowego z wkładką do kontrastu. Cost: 13 000 PLN
  2. cieplarka do hybrydyzacji. Cost: 5 000 PLN

Information in the final report

Publication in academic press/journals (5)

  1. Nuclear speckles: molecular organization, biological function and role in disease

    Authors:
    L. Gałgański, M. Urbanek, W. Krzyżosiak
    Academic press:
    Nucleic Acids Research (year: 2017, volume: 45, pages: 10350-10368), Publisher: OXFORD UNIV PRESS
    Status:
    Published
    DOI:
    10.1093/nar/gkx759 – link to the publication
  2. Somatic Mutations in miRNA Genes in Lung Cancer—Potential Functional Consequences of Non-Coding Sequence Variants

    Authors:
    P. Galka-Marciniak, M.O. Urbanek-Trzeciak, P.M. Nawrocka, A. Dutkiewicz, M. Giefing, M.A. Lewandowska, P. Kozlowski
    Academic press:
    Cancers (year: 2019, volume: 11(6), pages: 793), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers11060793 – link to the publication
  3. miRNAmotif-A Tool for the Prediction of Pre-miRNA⁻Protein Interactions

    Authors:
    MO Urbanek-Trzeciak, E Jaworska, WJ Krzyzosiak
    Academic press:
    International Journal of Molecular Sciences (year: 2018, volume: 19(12), pages: E4075), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19124075 – link to the publication
  4. Reduction of Huntington's Disease RNA Foci by CAG Repeat-Targeting Reagents

    Authors:
    M. Urbanek, A. Fiszer, W. Krzyżosiak
    Academic press:
    Frontiers in cellular neuroscience (year: 2017, volume: 11, pages: 82), Publisher: FRONTIERS MEDIA SA
    Status:
    Published
    DOI:
    10.3389/fncel.2017.00082 – link to the publication
  5. Pan-cancer analysis of somatic mutations in miRNA genes

    Authors:
    MO. Urbanek-Trzeciak, P. Galka-Marciniak, PM. Nawrocka, E. Kowal, S. Szwec, M. Giefing, P. Kozlowski
    Academic press:
    EBioMedicine (year: 2020, volume: 61, pages: 103051), Publisher: The Lancet
    Status:
    Published
    DOI:
    10.1016/j.ebiom.2020.103051 – link to the publication

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