Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Imaging miRNA biogenesis pathway and cellular localization of RNA interference triggers

2015/17/N/NZ3/03629

Keywords:

miRNA biogenesis RNA interference in situ hybridization RNA imaging in living cells

Descriptors:

  • NZ3_1: Cell biology
  • NZ1_1: Molecular biology
  • NZ3_2: Cell physiology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Martyna Urbanek-Trzeciak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 9 - announced on 2015-03-16

Amount awarded: 148 800 PLN

Project start date (Y-m-d): 2016-03-09

Project end date (Y-m-d): 2019-12-08

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. cieplarka do hybrydyzacji (5 000 PLN)
  2. Obiektyw 100x klasy plan fluorytowej do jasnego pola oraz kontrastu fazowego z wkładką do kontrastu (13 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Somatic Mutations in miRNA Genes in Lung Cancer—Potential Functional Consequences of Non-Coding Sequence Variants
    Authors:
    P. Galka-Marciniak, M.O. Urbanek-Trzeciak, P.M. Nawrocka, A. Dutkiewicz, M. Giefing, M.A. Lewandowska, P. Kozlowski
    Academic press:
    Cancers (rok: 2019, tom: 11(6), strony: 793), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cancers11060793 - link to the publication
  2. Nuclear speckles: molecular organization, biological function and role in disease
    Authors:
    L. Gałgański, M. Urbanek, W. Krzyżosiak
    Academic press:
    Nucleic Acids Research (rok: 2017, tom: 45, strony: 10350-10368), Wydawca: OXFORD UNIV PRESS
    Status:
    Published
    DOI:
    10.1093/nar/gkx759 - link to the publication
  3. Reduction of Huntington's Disease RNA Foci by CAG Repeat-Targeting Reagents
    Authors:
    M. Urbanek, A. Fiszer, W. Krzyżosiak
    Academic press:
    Frontiers in cellular neuroscience (rok: 2017, tom: 11, strony: 82), Wydawca: FRONTIERS MEDIA SA
    Status:
    Published
    DOI:
    10.3389/fncel.2017.00082 - link to the publication
  4. miRNAmotif-A Tool for the Prediction of Pre-miRNA⁻Protein Interactions
    Authors:
    MO Urbanek-Trzeciak, E Jaworska, WJ Krzyzosiak
    Academic press:
    International Journal of Molecular Sciences (rok: 2018, tom: 19(12), strony: E4075), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19124075 - link to the publication
  5. Pan-cancer analysis of somatic mutations in miRNA genes
    Authors:
    MO. Urbanek-Trzeciak, P. Galka-Marciniak, PM. Nawrocka, E. Kowal, S. Szwec, M. Giefing, P. Kozlowski
    Academic press:
    EBioMedicine (rok: 2020, tom: 61, strony: 103051), Wydawca: The Lancet
    Status:
    Published
    DOI:
    10.1016/j.ebiom.2020.103051 - link to the publication

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