Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The effect of soluble oat beta-glucans on non-specific colon inflammation

2015/17/B/NZ9/01740

Keywords:

beta glucan oat cytokines bacterial flora chronic inflammation rats transcriptomics colitis

Descriptors:

  • NZ9_7: Nutrition and food sciences

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Nauk o Żywieniu Człowieka i Konsumpcji

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Joanna Gromadzka-Ostrowska 

Number of co-investigators in the project: 12

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 801 200 PLN

Project start date (Y-m-d): 2016-02-19

Project end date (Y-m-d): 2020-02-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. wirówka MINISPIN z wirnikiem na 12 miejsc; producent Eppendorf.
  2. zamrażarka z wyposażeniem ULT (UUS-668B-1) + system awaryjnego chłodzenia i modem do powiadamiania SMS- o alarmie wysokiej temp (50 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (5)
  1. Time-Dependent Indirect Antioxidative Effects of Oat Beta-Glucans on Peripheral Blood Parameters in the Animal Model of Colon Inflammation
    Authors:
    3.Kopiasz Ł., Dziendzikowska K., Gajewska M., Wilczak J., Harasym J., Żyła E., Kamola D., Oczkowski M., Królikowski T., Gromadzka-Ostrowska J.
    Academic press:
    Antioxidants (rok: 2020, tom: 9, strony: 375-397), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antiox9050375 - link to the publication
  2. Proteinaceous residuals removal from oat beta-glucan extracts obtained with alkaline water extraction
    Authors:
    J. Harasym, E. Żyła, K. Dziendzikowska, J. Gromadzka-Ostrowska
    Academic press:
    Molecules (rok: 2019, tom: 24, strony: 1729-1745), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24091729 - link to the publication
  3. Anti-inflammatory activity of oat beta-glucans in a Crohn's Disease model: time- and molar mass-dependent effects
    Authors:
    Zyła E., Dziendzikowska K., Kamola D., Wilczak J., Sapierzynski R., Harasym J., and Gromadzka-Ostrowska J.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 4485), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22094485 - link to the publication
  4. Effects of dietary oat beta‐glucans on colon apoptosis and autophagy through TLRs and Dectin‐1 signaling pathways — Crohn's Disease model study
    Authors:
    Kopiasz Ł., Dziendzikowska K., Gajewska M., Oczkowski M., Majchrzak‐Kuligowska K., Królikowski T. and Gromadzka‐Ostrowska J.
    Academic press:
    Nutrients (rok: 2021, tom: 13, strony: 321), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu13020321 - link to the publication
  5. Beneficial effects of oat beta-glucan dietary supplementation in colitis depend on its molecular weight
    Authors:
    1.Żyła E., Dziendzikowska K., Gajewska M., Wilczak J., Harasym J., Gromadzka-Ostrowska J.
    Academic press:
    Molecules (rok: 2019, tom: 24, strony: 3591-3613), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules24193591 - link to the publication
  1. Beneficial effects of oat β-glucans on the large intestinal inflammation
    Authors:
    K. Dziendzikowska, E. Żyła, J. Wilczak, D. Kamola, M. Oczkowski, T. Królikowski, M. Gajewska, J. Harasym, J.Gromadzka-Ostrowska
    Conference:
    8th International Congress of Pathophysiology (rok: 2018, ), Wydawca: Congress Abstacts Book
    Data:
    konferencja 05 - 08 September
    Status:
    Published
  2. Effect of oats β-glucans on intestinal lymphocyte subpopulations in induced colitis
    Authors:
    T. Królikowski, E. Żyła, M. Oczkowski, K. Dziendzikowska, J. Wilczak, M. Gajewska, J. Harasym, J. Gromadzka-Ostrowska
    Conference:
    4th International Congress ''Food Quality, Technology and Safety and 18th International Symposium ''Feed Technology'' (rok: 2018, ), Wydawca: University of Novi Sad, Institute of Food Technology in Novi Sad
    Data:
    konferencja 23-35 October
    Status:
    Published
  3. Influence of well purifed oats β-glucans on inflammatory cytokines and its gene expression in rats with colon inflammation
    Authors:
    E. Żyła, K. Dziendzikowska, J. Wilczak, D. Kamola, M. Oczkowski, T. Królikowski, M. Gajewska, J. Harasym, J. Gromadzka-Ostrowska
    Conference:
    4th International Congress ''Food Quality, Technology and Safety and 18th International Symposium ''Feed Technology'' (rok: 2018, ), Wydawca: University of Novi Sad, Institute of Food Technology in Novi Sad
    Data:
    konferencja 23-35 October
    Status:
    Published
  4. The effects of oat β-glucans on antioxidant defense parameters in colon in rats with experimentally-induced colitis
    Authors:
    J. Wilczak, M. Oczkowski, E. Żyła, K. Dziendzikowska, M. Gajewska, T. Królikowski, J. Harasym, J. Gromadzka-Ostrowska
    Conference:
    4th International Congress ''Food Quality, Technology and Safety and 18th International Symposium ''Feed Technology'' (rok: 2018, ), Wydawca: University of Novi Sad, Institute of Food Technology in Novi Sad
    Data:
    konferencja 23-35 October
    Status:
    Published
  5. Therapeutic effect of highly purified oat beta-glucan on colon inflammation states - a model study
    Authors:
    J. Harasym, K. Dziendzikowska, J. Gromadzka-Ostrowska
    Conference:
    Food 2030: Towards s ustainable agri-food systems (rok: 2018, ), Wydawca: University of Hohenheim
    Data:
    konferencja 5-6 September
    Status:
    Published

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