Influence of the hinge region of mouse IgG3 antibodies on their unique features and functions.

2015/17/N/NZ1/00039

Keywords

Descriptors

  • NZ1_9: Biotechnologia
  • NZ1_2: Biochemia
  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Tomasz Jakub Klaus

Number of co-investigators in the project: 2

Call

PRELUDIUM 9 – announced on 2015-03-16

Amount awarded
149 320 PLN
Project start date
2016-02-01
Project end date
2019-01-31
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zestaw do elektroforezy DNA i białek z zasilaczem. Cost: 10 000 PLN

Information in the final report

Publication in academic press/journals (1)

  1. CH2 Domain of Mouse IgG3 Governs Antibody Oligomerization, Increases Functional Affinity to Multivalent Antigens and Enhances Hemagglutination.

    Authors:
    Tomasz Klaus, Joanna Bereta
    Academic press:
    Frontiers in Immunology (year: 2018, volume: 9, pages: 1096), Publisher: Holtzbrinck Publishing Group
    Status:
    Published
    DOI:
    10.3389/fimmu.2018.01096 – link to the publication

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Graphic design and implementation: Jakub Piotrowski