Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Ultrasound-sensitive O2 nanobubbles: oxygen delivery to tumors and its monitoring by Electron Paramagnetic Resonance imaging

2015/17/B/NZ7/03005

Keywords:

EPR imaging technology oxygenation nanobubbles

Descriptors:

  • ST5_10: Functional materials/nanomaterials, nanoparticles
  • NZ1_3: Biophysics
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Martyna Elas 

Number of co-investigators in the project: 5

Call: OPUS 9 - announced on 2015-03-16

Amount awarded: 940 491 PLN

Project start date (Y-m-d): 2016-02-25

Project end date (Y-m-d): 2019-12-24

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Analizator sygnału żródła E5052B (54 908 PLN)
  2. Przenośny aparat do USG wraz z sondą 18 MGz.
  3. Kontroler oddechu i EKG serca do bramkowania sygnału EPR (75 092 PLN)
  4. Termowizyjna kamera do pomiaru temperatury na odległość (11 448 PLN)
  5. Bank do przechowywania tkanek w ciekłym azocie.

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (1)
  1. Increasing oxygen tension in tumor tissue using ultrasound sensitive O2 microbubbles
    Authors:
    Agnieszka Drzał, Anthony Delalande, Gabriela Dziurman, Mylene Fournie, Chantal Pichon, Martyna Elas
    Academic press:
    Free Radical Biology and Medicine (rok: 2022, tom: 193, strony: 567-578), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.freeradbiomed.2022.11.005 - link to the publication
  2. Ultrasound sensitive O2 microbubbles radiosensitize cancer cells but lead to higher metastatic spread
    Authors:
    Agnieszka Drzał, Anthony Delalande, Gabriela Dziurman, Chantal Pichon, Jan Swakoń, Martyna Elas
    Academic press:
    Free Radical Biology and Medicine (rok: 2023, tom: brak, strony: brak), Wydawca: Elsevier
    Status:
    Submitted
  1. Electron Paramagnetic Resonance Imaging - Solo and Orchestra
    Authors:
    Elas M, Krzykawska-Serda M, Gonet M, Kozinska A, Plonka PM
    Book:
    Medical Imaging Methods. Recent Trends (rok: 2019, tom: brak tomu, strony: 15342), Wydawca: Springer
    Status:
    Published