Projects funded by the NCN
Role of sirtuin 2 (SIRT2) in the drug resistance of melanomas.
2015/17/B/NZ5/00142
Keywords:
SIRT2 melanoma regulation of expression
Descriptors:
- NZ5_1: Etiology of human diseases
- NZ2_2: Genomics, transcriptomics, epigenomics
- NZ3_7: Signal transduction
Panel:
NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)
Host institution :
Instytut Biologii Medycznej PAN
woj. łódzkie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: OPUS 9 - announced on 2015-03-16
Amount awarded: 577 200 PLN
Project start date (Y-m-d): 2016-02-25
Project end date (Y-m-d): 2019-10-24
Project duration:: 44 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (2)
- SIRT2 Contributes to the Resistance of Melanoma Cells to the Multikinase Inhibitor Dasatinib.Authors:Karwaciak I, Sałkowska A, Karaś K, Sobalska-Kwapis M, Walczak-Drzewiecka A, Pułaski Ł, Strapagiel D, Dastych J, Ratajewski M.Academic press:Cancers (Basel) (rok: 2019, tom: 11(5), strony: pii: E673), Wydawca: MDPIStatus:PublishedDOI:10.3390/cancers11050673 - link to the publication
- Targeting SIRT2 Sensitizes Melanoma Cells to Cisplatin via an EGFR-Dependent Mechanism.Authors:Karwaciak I, Sałkowska A, Karaś K, Dastych J, Ratajewski M.Academic press:International Journal of Molecular Sciences (rok: 2021, tom: 22(9), strony: 5034), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms22095034 - link to the publication