Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Regulation of RNA polymerase III in macrophages

2015/17/D/NZ1/00034

Keywords:

transcription RNA polimerase III macrophages NF-kappaB MAP kinases

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_1: Cell biology
  • NZ6_1: Adaptive and innate immunity

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Damian Graczyk 

Number of co-investigators in the project: 3

Call: SONATA 9 - announced on 2015-03-16

Amount awarded: 776 000 PLN

Project start date (Y-m-d): 2016-06-01

Project end date (Y-m-d): 2020-09-30

Project duration:: 52 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wirówka Eppendorf 5424R z chłodzeniem (30 000 PLN)
  2. Dewar do przechowywania komórek Taylor–Wharton LS3000 (20 000 PLN)
  3. Inkubator CO2 do hodowli komórkowych.
  4. Komputery.

Information in the final report

  • Publication in academic press/journals (3)
  1. MAP kinases are involved in RNA polymerase III regulation upon LPS treatment in macrophages
    Authors:
    Aneta Jurkiewicz, Damian Graczyk
    Academic press:
    Gene (rok: 2022, tom: 831, strony: 45299), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.gene.2022.146548 - link to the publication
  2. Regulation of tRNA synthesis by the general transcription factors of RNA polymerase III - TFIIIB and TFIIIC, and by the MAF1 protein
    Authors:
    Graczyk D., Cieśla M., Boguta M.
    Academic press:
    Biochimica et Biophysica Acta - Gene Regulatory Mechanisms (rok: 2018, tom: 1861, strony: 320-329), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbagrm.2018.01.011 - link to the publication
  3. Inhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic Acid
    Authors:
    Jurkiewicz A., Leśniewska E., Cieśla M, Gorjão N, Kantidakis T, White RJ, Boguta M, Graczyk D.
    Academic press:
    Molecular and Cellular Biology (rok: 2019, tom: 40, strony: 45305), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/MCB.00294-1 - link to the publication

O Narodowym Centrum Nauki

Finansowanie nauki

Współpraca zagraniczna

Centrum prasowe

Deklaracja dostępności
Przetwarzanie danych osobowych
Polityka cookies

Partnerzy