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Regulation of RNA polymerase III in macrophages

2015/17/D/NZ1/00034

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ3_1: Biologia komórki
  • NZ6_1: Odporność swoista i nieswoista

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Biochemii i Biofizyki PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Damian Jan Graczyk

Number of co-investigators in the project: 3

Call

SONATA 9 – announced on 2015-03-16

Amount awarded
776 000 PLN
Project start date
2016-06-01
Project end date
2020-09-30
Project duration
52 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dewar do przechowywania komórek Taylor–Wharton LS3000. Cost: 20 000 PLN
  2. Inkubator CO2 do hodowli komórkowych.
  3. Komputery.
  4. Wirówka Eppendorf 5424R z chłodzeniem. Cost: 30 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Inhibition of tRNA Gene Transcription by the Immunosuppressant Mycophenolic Acid

    Authors:
    Jurkiewicz A., Leśniewska E., Cieśla M, Gorjão N, Kantidakis T, White RJ, Boguta M, Graczyk D.
    Academic press:
    Molecular and Cellular Biology (year: 2019, volume: 40, pages: 46036), Publisher: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/MCB.00294-1 – link to the publication

  2. Regulation of tRNA synthesis by the general transcription factors of RNA polymerase III - TFIIIB and TFIIIC, and by the MAF1 protein

    Authors:
    Graczyk D., Cieśla M., Boguta M.
    Academic press:
    Biochimica et Biophysica Acta - Gene Regulatory Mechanisms (year: 2018, volume: 1861, pages: 320-329), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbagrm.2018.01.011 – link to the publication

  3. MAP kinases are involved in RNA polymerase III regulation upon LPS treatment in macrophages

    Authors:
    Aneta Jurkiewicz, Damian Graczyk
    Academic press:
    Gene (year: 2022, volume: 831, pages: 46030), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.gene.2022.146548 – link to the publication

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