Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Phytochemical analysis and evaluation of anti-inflammatory and antimicrobial activities of extracts prepared from pharmacopoeial plant material lime flower (Tiliae flos).

2015/17/D/NZ7/02641

Keywords:

lime flower anti-inflammatory activity antimicrobial activity neutrophils polyphenols natural products

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Sebastian Granica 

Number of co-investigators in the project: 6

Call: SONATA 9 - announced on 2015-03-16

Amount awarded: 484 280 PLN

Project start date (Y-m-d): 2016-01-27

Project end date (Y-m-d): 2020-01-26

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Sprzęt komputerowy - komputer (7 300 PLN)
  2. Profesjonalne oprogramowanie do analizy chemometrycznej (PCA, HCA) (5 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. The influence of procyanidins isolated from small-leaved lime flowers (Tilia cordata Mill.) on human neutrophils
    Authors:
    Monika E.Czerwińska, Marta K.Dudek, Karolina A.Pawłowska, AnnaPruś, Maria Ziaja, Sebastian Granica
    Academic press:
    Fitoterapia (rok: 2018, tom: 127, strony: 115-122), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.fitote.2018.02.018 - link to the publication
  2. UHPLC-DAD-MS/MS analysis of extracts from linden flowers (Tiliae flos): Differences in the chemical composition between five Tilia species growing in Europe
    Authors:
    Maria Ziaja, Karolina A.Pawłowska, Karolina Józefczyk, Anna Pruś, Joanna Stefańska, Sebastian Granica
    Academic press:
    Industrial Crops and Products (rok: 2020, tom: 154, strony: 112691), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.indcrop.2020.112691 - link to the publication
  3. Characterization of herbal teas containing lime flowers – Tiliae flos by HPTLC method with chemometric analysis
    Authors:
    Natalia Melnyk, Karolina A.Pawłowska, Maria Ziaja, Wojciech Wojnowski, Oleh Koshovyi, Sebastian Granica, Agnieszka Bazylko
    Academic press:
    Food Chemistry (rok: 2021, tom: 346, strony: 128929), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodchem.2020.128929 - link to the publication
  1. PHYTOCHEMICAL INVESTIGATIONS OF EXTRACTS PREPARED FROM FLOWERS OF TILIA CORDATA L.
    Authors:
    S. Granica, A. Pruś
    Conference:
    10th INTERNATIONAL SYMPOSIUM ON CHROMATOGRAPHY OF NATURAL PRODUCTS (rok: 2016, ), Wydawca: Chair and Dept. of Pharmacognosy with Medicinal Plant Unit of Medical University of Lublin, Lublin 2016
    Data:
    konferencja 6-9.06.2016
    Status:
    Published
  2. The UHPLC-DAD-MS3 analysis of pharmacopoeial plant material Tiliae flos. Comparison of the chemical composition of Tilia cordata and Tilia platyphyllos
    Authors:
    S Granica, A Pruś, M Ziaja
    Conference:
    Abstracts 9th Joint Meeting of AFERP, ASP, GA, JSP, PSE & SIF AFERP, ASP, GA, JSP, PSE & SIF (rok: 2016, ), Wydawca: Thieme
    Data:
    konferencja 24-27.07.2016
    Status:
    Published
    DOI:
    link to the publication

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