Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Ścieżki degradacji transkryptów związanych z chorobami człowieka, których podłożem jest ekspansja sekwencji mikrosatelitarnych

2015/16/S/NZ1/00086

Keywords:

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Chemii Bioorganicznej PAN

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Drążkowska 

Number of co-investigators in the project: 2

Call: FUGA 4 - announced on 2014-12-15

Amount awarded: 612 000 PLN

Project start date (Y-m-d): 2015-12-01

Project end date (Y-m-d): 2019-03-11

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  1. Elimination of 01/A'-A0 pre-rRNA processing by-product in human cells involves cooperative action of two nuclear exosome-associated nucleases: RRP6 and DIS3
    Authors:
    Kamil Kobyłecki, Karolina Drążkowska, Tomasz M. Kuliński, Andrzej Dziembowski, Rafał Tomecki
    Academic press:
    RNA (rok: 2018, tom: 24(12), strony: 1677-1692), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.066589.118 - link to the publication
  2. Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions
    Authors:
    Adam Ciesiolka, Magdalena Jazurek, Karolina Drazkowska, Wlodzimierz J. Krzyzosiak
    Academic press:
    FRONTIERS IN CELLULAR NEUROSCIENCE (rok: 2017, tom: 11, strony: art nr 97), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fncel.2017.00097 - link to the publication
  3. Cytoplasmic RNA Decay
    Authors:
    Karolina Drazkowska, Rafal Tomecki
    Academic press:
    Essential for Life Science (rok: 2017, tom: Mol Biology, strony: -), Wydawca: John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/9780470015902.a0027365 - link to the publication