Ścieżki degradacji transkryptów związanych z chorobami człowieka, których podłożem jest ekspansja sekwencji mikrosatelitarnych

2015/16/S/NZ1/00086

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_2: Biochemia

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Chemii Bioorganicznej PAN

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Karolina Wanda Drążkowska

Number of co-investigators in the project: 2

Call

FUGA 4 – announced on 2014-12-15

Amount awarded
612 000 PLN
Project start date
2015-12-01
Project end date
2019-03-11
Project duration
39 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (3)

  1. Cytoplasmic RNA Decay

    Authors:
    Karolina Drazkowska, Rafal Tomecki
    Academic press:
    Essential for Life Science (year: 2017, volume: Mol Biology, pages: -), Publisher: John Wiley & Sons
    Status:
    Published
    DOI:
    10.1002/9780470015902.a0027365 – link to the publication
  2. Elimination of 01/A'-A0 pre-rRNA processing by-product in human cells involves cooperative action of two nuclear exosome-associated nucleases: RRP6 and DIS3

    Authors:
    Kamil Kobyłecki, Karolina Drążkowska, Tomasz M. Kuliński, Andrzej Dziembowski, Rafał Tomecki
    Academic press:
    RNA (year: 2018, volume: 24(12), pages: 1677-1692), Publisher: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.066589.118 – link to the publication
  3. Structural Characteristics of Simple RNA Repeats Associated with Disease and their Deleterious Protein Interactions

    Authors:
    Adam Ciesiolka, Magdalena Jazurek, Karolina Drazkowska, Wlodzimierz J. Krzyzosiak
    Academic press:
    FRONTIERS IN CELLULAR NEUROSCIENCE (year: 2017, volume: 11, pages: art nr 97), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fncel.2017.00097 – link to the publication

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Graphic design and implementation: Jakub Piotrowski