Projects funded by the NCN
Structural modifications of bacterial endotoxins (lipopolysaccharides) of significant importance to future antibacterial therapeutic strategies.
2014/15/B/NZ6/03203
Keywords:
endotoxin lipopolysaccharide LPS sepsis enterobacterial common antigen ECA capsular antigen K antigen M antigen NMR mass spectrometry SPR interactions
Descriptors:
- NZ6_4: Bacteriology
- NZ6_1: Adaptive and innate immunity
Panel:
NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology
Host institution :
Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda, Polska Akademia Nauk
woj. dolnośląskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 5
Call: OPUS 8 - announced on 2014-09-15
Amount awarded: 728 320 PLN
Project start date (Y-m-d): 2015-09-30
Project end date (Y-m-d): 2019-09-29
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Komora laminarna II klasy bezpieczeństwa.
- Komputer osobisty typu notebook (6 346 PLN)
- Wirówka preparatywna z rotorem wychyłowym i adapterem 4 x 750 ml (70 000 PLN)
Information in the final report
- Publication in academic press/journals (3)
- Lipopolysaccharide-Linked Enterobacterial Common Antigen (ECA LPS) Occurs in Rough Strains of Escherichia coli R1, R2, and R4Authors:Anna Maciejewska, Marta Kaszowska, Wojciech Jachymek, Czeslaw Lugowski, Jolanta LukasiewiczAcademic press:International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 21(17), 6038), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms21176038 - link to the publication
- Structural Studies of the Lipopolysaccharide Isolated from Plesiomonas shigelloides O22:H3 (CNCTC 90/89)Authors:Anna Maciejewska, Brygida Bednarczyk, Czeslaw Lugowski, Jolanta LukasiewiczAcademic press:International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 21(18), 6788), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms21186788 - link to the publication
- A New Look at the Enterobacterial Common Antigen Forms Obtained during Rough Lipopolysaccharides PurificationAuthors:Tomasz K Gozdziewicz, Anna Maciejewska, Alona Tsybulska, Czeslaw Lugowski and Jolanta LukasiewiczAcademic press:International Journal of Molecular Sciences (rok: 2021, tom: nie przypisano, strony: 701), Wydawca: MDPIStatus:PublishedDOI:10.3390/ijms - link to the publication