Carbon monoxide (CO) as a physiological gastroprotective factor and modulator of hydrogen sulfide (H2S) sythesis pathways in experimental gastric mucosal damage induced by aspirin.
2014/15/N/NZ4/04564
Keywords
Descriptors
- NZ4_2: Fizjologia
- NZ1_2: Biochemia
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Lekarski
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
PRELUDIUM 8 – announced on 2014-09-15
- Amount awarded
- 66 660 PLN
- Project start date
- 2015-07-13
- Project end date
- 2017-05-12
- Project duration
- 22 months (the same as in the proposal)
- Project status
- Project settled
Information in the final report
Publication in academic press/journals (2)
-
Interaction between endogenous carbon monoxide and hydrogen sulfide in the mechanism of gastroprotection against acute aspirin-induced gastric damage.
- Authors:
- Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Bakalarz D, Sliwowski Z, Pajdo R, Kwiecien S, Brzozowski T
- Academic press:
- Pharmacological Research (year: 2016, volume: 114, pages: 235-250), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.phrs.2016.11.001 – link to the publication
-
Nitric oxide, afferent sensory nerves, and antioxidative enzymes in the mechanism of protection mediated by tricarbonyldichlororuthenium(II) dimer and sodium hydrosulfide against aspirin-induced gastric damage.
- Authors:
- Magierowski M, Hubalewska-Mazgaj M, Magierowska K, Wojcik D, Sliwowski Z, Kwiecien S, Brzozowski T
- Academic press:
- Journal of Gastroenterology (year: 2017, volume: 2017, pages: 46034), Publisher: Springer
- Status:
- Published
- DOI:
- 10.1007/s00535-017-1323-4 – link to the publication
Articles in post-conference publications (3)
-
Gastroprotective effect of hydrogen sulfide and carbon monoxide against aspirin-induced damage: involvement of heme oxygenase-1 and transcription factor Nrf-2
- Authors:
- Magierowska K, Magierowski M, Kwiecien S, Adamski J, Hubalewska-Mazgaj M, Sliwowski Z, Brzozowski T
- Conference:
- 4th International Conference on the Biology of Hydrogen Sulfide, Naples, Italy (year: 2016, pages: 147-149), Publisher: DIPARTIMENTO DI FARMACIA UNIVERSITA' DI NAPOLI FEDERICO II
- Date:
- conference 3-5 czerwiec 2016
- Status:
- Published
- DOI:
- link to the publication
-
Gaseous mediators as a protective molecules against acute gastric damage (in 9th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection
- Authors:
- Magierowska K, Magierowski M, Kwiecien S, Adamski J, Hubalewska-Mazgaj M, Sliwowski Z, Brzozowski T
- Conference:
- 9th International Symposium on Cell/Tissue Injury and Cytoprotection/Organoprotection (ISTICO) (year: 2016, pages: 14-15), Publisher: Symposion
- Date:
- conference 15-17 wrzesień 2016
- Status:
- Published
-
EVIDENCE FOR ANTIOXIDATIVE AND ANTIINFLAMMATORY PROPERTIES OF CARBON MONOXIDE AND HYDROGEN SULFIDE IN PATHOPHYSIOLOGY OF ASPIRIN-INDUCED GASTRIC DAMAGE
- Authors:
- Magierowski M, Magierowska K, Hubalewska-Mazgaj M, Adamski J, Sliwowski Z, Wojcik D, Kwiecien S, Brzozowski T
- Conference:
- United European Gastroenterology Week 2016 (year: 2016, pages: A490), Publisher: United European Gastroenterology Journal; ISSN 2050-6406 (Print); ISSN 2050-6414 (Online)
- Date:
- conference 15-19 październik 2016
- Status:
- Published
- DOI:
- link to the publication