Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of the impact of endocrine disruptors on the prevalence and clinical course of the polycystic ovary syndrome (PCOS).

2014/15/B/NZ7/00999

Keywords:

PCOS endocrine disruptors bisphenol phtalates plastificator

Descriptors:

  • NZ8_8: Ecotoxicology
  • NZ5_3: Pathogenesis of human diseases
  • NZ7_2: Environment and health risks

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Nauk o Zdrowiu z Oddziałem Pielęgniarstwa i Instytutem Medycyny Morskiej i Tropikalnej

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Dominik Rachoń 

Number of co-investigators in the project: 15

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 1 308 064 PLN

Project start date (Y-m-d): 2015-07-16

Project end date (Y-m-d): 2019-07-15

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zamrażarka (40 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. Serum bisphenol A analogues in women diagnosed with the polycystic ovary syndrome - is there an association?
    Authors:
    Jurewicz Joanna, Majewska Joanna, Berg Andrzej, Owczarek Katarzyna, Zajdel Radosław, Kaleta Dorota, Wasik Andrzej, Rachoń Dominik
    Academic press:
    Environ. Pollut. (rok: 2021, tom: 272, strony: 45298), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.envpol.2020.115962 - link to the publication
  2. Transcriptomic profile of cell cycle progression genes in human ovarian granulosa cells.
    Authors:
    M. Brązert, D. Iżycki, W. Kranc, B. Borowiec, M. Popis, P. Celichowski, K. Ożegowska, M. Jankowski, M. Jeseta, L. Pawelczyk, A. Bręborowicz, D. Rachoń, M. Nowicki, M. Kempisty
    Academic press:
    Journal of BIOLOGICAL REGULATORS & Homeostatic Agents (rok: 2019, tom: 33, strony: 39-51), Wydawca: Biolife
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  3. 'Heart development and morphogenesis' is a novel pathway for human ovarian granulosa cell differentiation during long‑term in vitro cultivation‑a microarray approach.
    Authors:
    Wiesława Kranc, Maciej Brązert, Piotr Celichowski, Artur Bryja, Mariusz J. Nawrocki, Katarzyna Ożegowska, Maurycy Jankowski, Michal Jeseta, Leszek Pawelczyk, Andrzej Bręborowicz, Dominik Rachoń, Mariusz T. Skowroński, Małgorzata Bruska, Maciej Zabel, Michał Nowicki, Bartosz Kempisty
    Academic press:
    Molecular Medicine Reports (rok: 2019, tom: 19, strony: 1705-1715), Wydawca: Molecular Publications
    Status:
    Published
    DOI:
    10.3892/mmr.2019.9837 - link to the publication
  4. Determination of trace levels of eleven bisphenol A analogues in human blood serum by high performance liquid chromatography–tandem mass spectrometry
    Authors:
    Katarzyna Owczarek, Paweł Kubica, Błażej Kudłak, Aleksandra Rutkowska, Aleksandra Konieczna, Dominik Rachoń, Jacek Namieśnik, Andrzej Wasik
    Academic press:
    Science of the Total Environment (rok: 2018, tom: 628-629, strony: 1362-1368), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.scitotenv.2018.02.148 - link to the publication
  5. Serum bisphenol A concentrations measured using high performance liquid chromatography tandem mass spectrometry in women with polycystic ovary syndrome
    Authors:
    Aleksandra Konieczna, Dominik Rachon, Katarzyna Owczarek, Paweł Kubica, Agnieszka Kowaleska, Błażej Kudłak, Andrzej Wasik, Jacek Namieśnik,
    Academic press:
    Reproductive Toxicology (rok: 2018, tom: 82, strony: 32-37), Wydawca: European Journal of Endocrinology
    Status:
    Published
    DOI:
    10.1016/j.reprotox.2018.09.006 - link to the publication
  6. Genes responsible for proliferation, differentiation and junction adhesion are significantly up-regulated in human ovarian granulosa cells during long-term primary culture in vitro
    Authors:
    Wiesława Kranc; Maciej Brązert; Joanna Dudna, Piotr Celichowski; Artur Bryja; Mariusz Nawrocki; Katarzyna Ożegowska; Maurycy Jankowski; Błażej Chermuła; Marta Dyszkiewicz-Konwińska; Michal Jeseta; Leszek Pawelczyk; Andrzej Bręborowicz; Dominik Rachoń; Małgorzata Bruska; Michał Nowicki; Maciej Zabel; Bartosz Kempisty
    Academic press:
    Histochemistry and Cell Biology (rok: 2019, tom: 151, strony: 125-143), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00418-018-1750-1 - link to the publication
  7. GENES INVOLVED IN HORMONE METABOLISM AND CELLULAR RESPONSE IN HUMAN OVARIAN GRANULOSA CELLS
    Authors:
    M. BRĄZERT, D. IŻYCKI, W. KRANC, B. BOROWIEC, M. POPIS, K. OŻEGOWSKA, A. BRĘBOROWICZ, D. RACHOŃ, M. NOWICKI, B. KEMPISTY
    Academic press:
    JOURNAL OF BIOLOGICAL REGULATORS & HOMEOSTATIC AGENTS (rok: 2019, tom: 33, strony: 461-468), Wydawca: Biolife
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication

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