Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of p66Shc in the oxidative stress associated with defects in complex I of the mitochondrial respiratory chain

2014/15/N/NZ3/02155

Keywords:

mitochondria oxidative stress p66Shc mitochondrial diseases complex I

Descriptors:

  • NZ3_2: Cell physiology
  • NZ3_14: Other related subjects

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Aleksandra Wojtala 

Number of co-investigators in the project: 2

Call: PRELUDIUM 8 - announced on 2014-09-15

Amount awarded: 75 000 PLN

Project start date (Y-m-d): 2015-07-23

Project end date (Y-m-d): 2017-01-22

Project duration:: 18 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (1)
  1. Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway
    Authors:
    Aleksandra Wojtala, Agnieszka Karkucinska-Wieckowska, Vilma A. Sardao, Joanna Szczepanowska, Maciej Pronicki, Jerzy Duszynski, Mariusz R. Wieckowski
    Academic press:
    Mitochondrion (rok: 2017, tom: nie dotyczy, strony: nie dotyczy), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mito.2017.07.002 - link to the publication