The role of p66Shc in the oxidative stress associated with defects in complex I of the mitochondrial respiratory chain

2014/15/N/NZ3/02155

Keywords

Descriptors

  • NZ3_2: Fizjologia komórki
  • NZ3_14: Inne zagadnienia pokrewne

Panel

NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Aleksandra Barbara Wojtala

Number of co-investigators in the project: 2

Call

PRELUDIUM 8 – announced on 2014-09-15

Amount awarded
75 000 PLN
Project start date
2015-07-23
Project end date
2017-01-22
Project duration
18 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (1)

  1. Modulation of mitochondrial dysfunction-related oxidative stress in fibroblasts of patients with Leigh syndrome by inhibition of prooxidative p66Shc pathway

    Authors:
    Aleksandra Wojtala, Agnieszka Karkucinska-Wieckowska, Vilma A. Sardao, Joanna Szczepanowska, Maciej Pronicki, Jerzy Duszynski, Mariusz R. Wieckowski
    Academic press:
    Mitochondrion (year: 2017, volume: nie dotyczy, pages: nie dotyczy), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.mito.2017.07.002 – link to the publication

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