Projects funded by the NCN
Analysis of the inflammatory role of MCPIP2 using the CRISPR/dCas9-FokI system. Identification of MCPIP2 substrates and interacting proteins, as well as factors controlling MCPIP2 expression.
2014/15/B/NZ2/03379
Keywords:
genome modification transcriptome analysis regulation of transcripts half-life inflammation
Descriptors:
- NZ2_1: Molecular genetics
- NZ2_3: Proteomics
- NZ2_2: Genomics, transcriptomics, epigenomics
Panel:
NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 4
Call: OPUS 8 - announced on 2014-09-15
Amount awarded: 851 570 PLN
Project start date (Y-m-d): 2015-11-24
Project end date (Y-m-d): 2019-11-23
Project duration:: 48 months (the same as in the proposal)
Project status: Project settled
Equipment purchased [PL]
- Kołyska laboratoryjna (5 000 PLN)
- Wirówka z chłodzeniem na probówki typu eppendorf (18 000 PLN)
- Mieszadło hematologiczne rolkowe (1 500 PLN)
- Mieszadło typu vortex (2 000 PLN)
- Miniwirówka do eppendorfów do PCR (600 PLN)
- Rotator wertykalny z regulacją kąta wychylania i prędkości (3 200 PLN)
- Mieszadło magnetyczne (2 000 PLN)
- Waga analityczna (3 000 PLN)
Information in the final report
- Publication in academic press/journals (3)
- The homeostatic function of Regnase-2 restricts neuroinflammation.Authors:Weronika Sowinska1, Mateusz Wawro1, Debolina D. Biswas2, Jakub Kochan1, Katarzyna Pustelny1, Aleksandra Solecka1, Angela S. Gupta2, Karli Mockenhaupt2, Jarosław Polak3, Borys Kwinta3, Tomasz Kordula2#, and Aneta Kasza1#Academic press:FASEB Journal (rok: 2023, tom: 37, strony: e22798), Wydawca: WileyStatus:PublishedDOI:10.1096/fj.202201978R - link to the publication
- ZC3H12B/MCPIP2, a new active member of the ZC3H12 family.Authors:Mateusz Wawro, Karolina Wawro, Jakub Kochan, Aleksandra Solecka, Weronika Sowińska, Agata Lichawska-Cieslar, Jolanta Jura, Aneta KaszaAcademic press:RNA Journal (rok: 2019, tom: 25(7), strony: 840-856), Wydawca: Cold Spring Harbor Laboratory Press on behalf of the RNA Society (United States)Status:PublishedDOI:10.1261/rna.071381.119 - link to the publication
- Potential limitations of the Sleeping Beauty transposon use in gene expression studies.Authors:Sowińska W, Wawro M, Solecka A, Kasza A.Academic press:Acta Biochim Pol. (rok: 2019, tom: 66(3), strony: 263-268), Wydawca: The Polish Biochemical Society and the Polish Academy of ScienceStatus:PublishedDOI:10.18388/abp.2019_2839 - link to the publication