Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Nanostructured materials as a platform for synthesis and delivery of therapeutical substances

2014/15/B/ST5/04498

Keywords:

2D zeolites MOFs drug delivery formulation MRI FTIR

Descriptors:

  • ST5_6: Porous materials, ceramics, glasses
  • ST5_8: Metals, alloys
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Wiesław Roth 

Number of co-investigators in the project: 9

Call: OPUS 8 - announced on 2014-09-15

Amount awarded: 902 720 PLN

Project start date (Y-m-d): 2015-07-16

Project end date (Y-m-d): 2020-02-15

Project duration:: 55 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mathematica (6 000 PLN)
  2. Mathstatica.
  3. System do badania porowatości metodą quasi-równowagowej temperaturowo-programowanej desorpcji i adsorpcji (QE-TPDA) (45 000 PLN)
  4. spektrometr FT-NIR-MIR z przystawką ATR (170 000 PLN)
  5. Mieszadło magnetyczne.

Information in the final report

  • Publication in academic press/journals (9)
  1. An inhalable theranostic system for local tuberculosis treatment containing an isoniazid loaded Metal Organic Framework Fe-MIL-101-NH2 - from raw MOF to drug delivery system
    Authors:
    125.G. Wyszogrodzka-Gaweł, P. Dorożyński, S. Giovagnoli, W. Strzempek, E. Pesta, W. P. Węglarz, B. Gil, E. Menaszek, P. Kulinowski
    Academic press:
    Pharmaceutics (rok: 2019, tom: 11, strony: 687-712), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics11120687 - link to the publication
  2. Interconversion of the CDO Layered Precursor ZSM-55 between FER and CDO Frameworks by Controlled Deswelling and Reassembly
    Authors:
    W. J. Roth, B. Gil, W. Makowski, A. Sławek, J. Grzybek, M. Kubu, J. Čejka
    Academic press:
    Chemistry of Materials (rok: 2016, tom: 28, strony: 3616-3619), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.chemmater.6b01302 - link to the publication
  3. A new layered MWW zeolite synthesized with the bifunctional surfactant template and the updated classification of layered zeolite forms obtained by direct synthesis
    Authors:
    J. Grzybek, W.J. Roth, B. Gil, A. Korzeniowska, M. Mazur, J. Čejka, R.E. Morris
    Academic press:
    Journal of Materials Chemistry A (rok: 2019, tom: 7, strony: 7701-7709), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C8TA09826C - link to the publication
  4. Fe-MIL-100 as drug delivery system for asthma and chronic obstructive pulmonary disease treatment and diagnosis
    Authors:
    W. Strzempek, E. Menaszek, B. Gil
    Academic press:
    Microporous and Mesoporous Materials (rok: 2019, tom: 280, strony: 264-270), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micromeso.2019.02.018 - link to the publication
  5. Incorporation and release of a model drug, ciprofloxacin, from non-modified SBA-15 molecular sieves with different pore sizes
    Authors:
    A. Korzeniowska, W. Strzempek, W. Makowski, E. Menaszek, W. J. Roth, B. Gil
    Academic press:
    Microporous and Mesoporous Materials (rok: 2020, tom: 294, strony: 109903), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micromeso.2019.109903 - link to the publication
  6. Pillaring of layered zeolite precursors with ferrierite topology leading to unusual molecular sieves on the micro/mesoporous border
    Authors:
    Wieslaw J. Roth, Barbara Gil, Alvaro Mayoral, Justyna Grzybek, Aleksandra Korzeniowska, Martin Kubu, Wacław Makowski, Jiří Čejka, Zbigniew Olejniczak, Michal Mazur
    Academic press:
    Dalton Transactions (rok: 2018, tom: 47, strony: 3029-3037), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/c7dt03718j - link to the publication
  7. Iron-based Metal-Organic Framework as a theranostic carrier for local tuberculosis therapy
    Authors:
    116.G. Wyszogrodzka, P. Dorożynski, B. Gil, W. J. Roth, M. Strzempek, B. Marszałek, W. P. Węglarz, E. Menaszek, W. Strzempek, P. Kulinowski
    Academic press:
    Pharmaceutical Research (rok: 2018, tom: 35, strony: 144-155), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11095-018-2425-2 - link to the publication
  8. Metal-organic frameworks: mechanisms of antibacterial action and potential applications
    Authors:
    G. Wyszogrodzka, B. Marszałek, B. Gil, P. Dorożyński
    Academic press:
    Drug Discovery Today (rok: 2016, tom: 21, strony: 1009-1018), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.drudis.2016.04.009 - link to the publication
  9. Liquid dispersions of zeolite monolayers with high catalytic activity prepared by soft-chemical exfoliation
    Authors:
    W.J. Roth, T. Sasaki, K. Wolski, Y. Song, D.-M. Tang, Yasuo Ebina, Renzhi Ma, J. Grzybek, K. Kałahurska, B. Gil, M. Mazur, S. Zapotoczny, J. Cejka,
    Academic press:
    Science Advances (rok: 2020, tom: 6, strony: sciadv.aay816), Wydawca: American Association for the Advancement of Science
    Status:
    Published
    DOI:
    10.1126/sciadv.aay8163 - link to the publication

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