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Information on the principal investigator and host institution

Information of the project and the call

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Intrinsically fluorescent dendrimers - spectrofluorimetric and cell biology studies

2014/14/M/NZ3/00498

Keywords:

dendrimer imaging fluorescence cell biology

Descriptors:

  • NZ3_1: Cell biology
  • ST5_21:
  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Łódzki, Wydział Biologii i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Barbara Klajnert-Maculewicz 

Number of co-investigators in the project: 6

Call: HARMONIA 6 - announced on 2014-06-16

Amount awarded: 869 700 PLN

Project start date (Y-m-d): 2015-06-08

Project end date (Y-m-d): 2019-02-07

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (8)
  • Articles in post-conference publications (4)
  1. Dendrimers for fluorescence-based bioimaging
    Authors:
    P. Trzepinski, B. Klajnert-Maculewicz
    Academic press:
    Journal of Chemical Technology and Biotechnology (rok: 2017, tom: 92, strony: 1157-1166), Wydawca: WILEY
    Status:
    Published
    DOI:
    10.1002/jctb.5216 - link to the publication
  2. Synthesis, internalization and visualization of N-(4-Carbomethoxy) pyrrolidone terminated PAMAM [G5:G3-TREN] tecto(dendrimers) in mammalian cells
    Authors:
    M. Studzian, P. Działak, Ł. Pułaski, D. M. Hedstrand, D. A. Tomalia, B. Klajnert-Maculewicz
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 4406-4424), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25194406 - link to the publication
  3. Non-traditional intrinsic luminescence (NTIL): Dynamic quenching demonstrates the presence of two distinct fluorophore types associated with NTIL behavior in pyrrolidone-terminated PAMAM dendrimers
    Authors:
    M. Studzian, Ł. Pułaski, D. A. Tomalia, B. Klajnert-Maculewicz
    Academic press:
    J. Phys. Chem. C (rok: 2019, tom: 123, strony: 18007-18016), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcc.9b02725 - link to the publication
  4. Modified PAMAM dendrimer with 4-carbomethoxypyrrolidone surface groups - its uptake, efflux, and location in a cell
    Authors:
    A. Janaszewska, M. Studzian, J. F. Petersen, M. Ficker, V. Paolucci, J. B. Christensen, D. A. Tomalia, B. Klajnert-Maculewicz
    Academic press:
    Colloids and Surfaces B (rok: 2017, tom: 159, strony: 211-216), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2017.07.052 - link to the publication
  5. Determination of non-traditional intrinsic fluorescence (NTIF) emission sites in 1-(4-carbomethoxypyrrolidone)-PAMAM dendrimers using CNDP-based quenching studies
    Authors:
    M. Konopka, A. Janaszewska, K. A. M. Johnson, D. Hedstrand, D. A. Tomalia, B. Klajnert-Maculewicz
    Academic press:
    J. Nanoparticle Res. (rok: 2018, tom: 20, strony: 220-230), Wydawca: SPRINGER
    Status:
    Published
    DOI:
    10.1007/s11051-018-4310-7 - link to the publication
  6. Intrinsic fluorescence of PAMAM dendrimers – quenching studies
    Authors:
    M. Konopka, A. Janaszewska, B. Klajnert-Maculewicz
    Academic press:
    Polymers (rok: 2018, tom: 10, strony: 540-547), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym10050540 - link to the publication
  7. Non-traditional intrinsic luminescence: inexplicable blue fluorescence observed for dendrimers, macromolecules and small molecular structures lacking traditional/conventional luminophores
    Authors:
    D. A. Tomalia, B. Klajnert-Maculewicz, K. A. M. Johnson, H. F. Brinkman, A. Janaszewska, D. M. Hedstrand
    Academic press:
    Progress Polymer Science (rok: 2019, tom: 90, strony: 35-117), Wydawca: PERGAMON-ELSEVIER SCIENCE LTD
    Status:
    Published
    DOI:
    10.1016/j.progpolymsci.2018.09.004 - link to the publication
  8. Pyrrolidone modification prevents PAMAM dendrimers from activation of pro-inflammatory signaling pathways in human monocytes
    Authors:
    A. Janaszewska, M. Gorzkiewicz, M. Ficker, J. F. Petersen, V. Paolucci, J. B. Christensen, B. Klajnert-Maculewicz
    Academic press:
    Molecular Pharmaceutics (rok: 2018, tom: 15, strony: 45646), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.molpharmaceut.7b00515 - link to the publication
  1. Intrinsic fluorescence of pyrrolidone-modified PAMAM Dendrimers – cell studies.
    Authors:
    B. Klajnert-Maculewicz, A. Janaszewska, M. Studzian, J. F. Petersen, M. Ficker, J. B. Christensen, D. A. Tomalia
    Conference:
    CLINAM 9 European & Global Summit for Cutting-Edge Medicine (rok: 2016, ), Wydawca: CLINAM Foundation
    Data:
    konferencja 26-29 czerwca 2016 r.
    Status:
    Published
  2. Fluorescent dendrimers without fluorophores
    Authors:
    M. Konopka, M. Studzian, A. Janaszewska, D. A. Tomalia, J. B. Christensen, B. Klajnert-Maculewicz
    Conference:
    Biodendrimer 2018: 6th International Symposium on Biomedical Applications of Dendrimers (rok: 2018, ), Wydawca: University of Urbino
    Data:
    konferencja 4-7 czerwca
    Status:
    Published
  3. Localization of fluorescent pyrrolidone-modified PAMAM dendrimers in cells by confocal microscopy
    Authors:
    B. Klajnert-Maculewicz, A. Janaszewska, M. Studzian, J. F. Petersen, M. Ficker, J. B. Christensen, D. A. Tomalia
    Conference:
    5th International Symposium on Biomedical Applications of Dendrimers (rok: 2016, ), Wydawca: University of Copenhagen
    Data:
    konferencja 2-5 sierpnia 2016 r.
    Status:
    Published
  4. Autofluorescence of PAMAM dendrimers with 4-carbomethoxy-pyrrolidone surface
    Authors:
    M. Konopka, A. Janaszewska, D. Tomalia, B. Klajnert-Maculewicz
    Conference:
    CLINAM 9 European & Global Summit for Cutting-Edge Medicine. (rok: 2016, ), Wydawca: CLINAM Foundation
    Data:
    konferencja 26-29 czerwca 2016 r.
    Status:
    Published

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