Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

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The role of indoleamine-2,3-dioxygenase in development of antitumor immune response tiggered by photodynamic therapy

2014/13/D/NZ6/01080

Keywords:

photodynamic therapy indoleamine-2,3-dioxygenase

Descriptors:

  • NZ6_8: Other related subjects
  • NZ1_1: Molecular biology
  • NZ5_9: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Angelika Muchowicz 

Number of co-investigators in the project: 2

Call: SONATA 7 - announced on 2014-03-17

Amount awarded: 691 987 PLN

Project start date (Y-m-d): 2015-02-02

Project end date (Y-m-d): 2018-08-01

Project duration:: 42 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  1. Inhibition of lymphangiogenesis impairs antitumour effects of photodynamic therapy and checkpoint inhibitors in mice
    Authors:
    Angelika Muchowicz, Malgorzata Wachowska, Joanna Stachura, Katarzyna Tonecka, Magdalena Gabrysiak, Dominika Wołosz, Zofia Pilch, Witold W. Kilarski, Louis Boon, Tomasz J. Klaus, Jakub Golab
    Academic press:
    European Journal of Cancer (rok: 2017, tom: 2017 Sep;83:, strony: 19-27), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejca.2017.06.004. - link to the publication
  2. Inhibition of IDO leads to IL-6-dependent systemic inflammation in mice when combined with photodynamic therapy
    Authors:
    Malgorzata Wachowska, Joanna Stachura, Katarzyna Tonecka, Klaudyna Fidyt, Agata Braniewska, Zuzanna Sas, Iwona Kotula, Tomasz P Rygiel, Louis Boon, Jakub Golab, Angelika Muchowicz
    Academic press:
    Cancer Immunology, Immunotherapy , Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    10.1007/s00262-020-02528-5 - link to the publication