Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Elucidating the gene regulatory network of zebrafish heart development using genomics

2014/13/B/NZ2/03863

Keywords:

Zebrafish congenital heart defect ChIP-seq genomics epigenomics

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_3: Proteomics
  • NZ3_2: Cell physiology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Międzynarodowy Instytut Biologii Molekularnej i Komórkowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Cecilia Winata 

Number of co-investigators in the project: 3

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 955 500 PLN

Project start date (Y-m-d): 2015-01-23

Project end date (Y-m-d): 2018-01-22

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Bioanalyzer (50 000 PLN)
  2. Bioinformatyczny sprzęt komputerowy (15 000 PLN)
  3. Systemy do elektroforezy białek i technik typu "Western-blot" (10 000 PLN)
  4. Zestaw hodowlany Danio rerio (98 000 PLN)
  5. Inkubator - 2 sztuki (60 791 PLN)
  6. Transiluminator z pokrywą.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (3)
  1. Dynamics of cardiomyocyte transcriptome and chromatin landscape demarcates key events of heart development
    Authors:
    Michal Pawlak, Katarzyna Z. Kedzierska, Maciej Migdal, Karim Abu Nahia, Jordan A. Ramilowski, Lukasz Bugajski, Kosuke Hashimoto, Aleksandra Marconi, Katarzyna Piwocka, Piero Carninci, and Cecilia L. Winata
    Academic press:
    Genome Research (rok: 2019, tom: 29(3), strony: 506-519), Wydawca: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1101/gr.244491.118 - link to the publication
  2. Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal to zygotic transition
    Authors:
    Winata CL, Łapiński M, Pryszcz L, Vaz C, Bin Ismail MH, Nama S, Hajan HS, Lee SGP, Korzh V, Sampath P, Tanavde V, Mathavan S.
    Academic press:
    Development (rok: 2018, tom: 45299, strony: 145(1)), Wydawca: Company of Biologists Ltd
    Status:
    Published
    DOI:
    10.1242/dev.159566 - link to the publication
  3. The canonical way to make a heart: β-catenin and plakoglobin in heart development and remodeling
    Authors:
    Piven Oksana, Winata Cecilia
    Academic press:
    Experimental Biology and Medicine (rok: 2017, tom: 242(18), strony: 1735-1745), Wydawca: SAGE Publications Inc.
    Status:
    Published
    DOI:
    10.1177/1535370217732737 - link to the publication
  1. Elucidating the gene regulatory network of zebrafish heart development using genomics
    Authors:
    Niescierowicz, Katarzyna ; Lapinski, Maciej ; Abu Nahia, K ; Carvalho, Ana Leonor ; Winata, Cecilia
    Conference:
    18th International Congress of Developmental Biology (rok: 2017, ), Wydawca: ELSEVIER SCIENCE BV
    Data:
    konferencja JUN 18-22, 2017
    Status:
    Published
  2. Genomics dissection of the zebrafish heart
    Authors:
    Pawlak, Michal ; Kedzierska, Katarzyna ; Bugajski, Lukasz ; Hashimoto, Kosuke ; Ramilowski, Jordan ; Marconi, Aleksandra ; Carninci, Piero ; Piwocka, Katarzyna; Winata, Cecilia
    Conference:
    18th International Congress of Developmental Biology (rok: 2017, ), Wydawca: ELSEVIER SCIENCE BV
    Data:
    konferencja JUN 18-22, 2017
    Status:
    Published
  3. Identification of epigenomic regulatory network of heart development
    Authors:
    Michal Pawlak, Katarzyna Kedzierska, Maciej Migdal, Karim Abu Nahia, Hashimoto Kosuke, Jordan Ramilowski, Lukasz Bugajski, Aleksandra Marconi, Katarzyna Piwocka, Piero Carninci, Cecilia Winata
    Conference:
    Human Genome Meeting 2018 (rok: 2018, ), Wydawca: Human Genome Organization
    Data:
    konferencja 12 - 15 March
    Status:
    Published