Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The role cytokines associated with allergic inflammation and microRNA regulation in rhinovirus infections in asthma

2014/13/B/NZ3/02393

Keywords:

asthma airway epithelium rhinovirus infection microRNA cytokines anti-viral response

Descriptors:

  • NZ3_1: Cell biology
  • NZ5_3: Pathogenesis of human diseases

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Bogdan Jakieła 

Number of co-investigators in the project: 3

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 817 440 PLN

Project start date (Y-m-d): 2015-02-18

Project end date (Y-m-d): 2020-02-17

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Mini-wirówka laboratoryjna (2 szt.) (4 200 PLN)
  2. Sterylizator parowy.
  3. Wirówka z rotorem do probówek 1.5 mL z chłodzeniem (27 000 PLN)

Information in the final report

  • Publication in academic press/journals (5)
  1. Dual role of the miR-146 family in rhinovirus-induced airway inflammation and allergic asthma exacerbation
    Authors:
    Laanesoo A, Urgard E, Periyasamy K, Laan M, Bochkov YA, Aab A, Magilnick N, Pooga M, Gern JE, Johnston SL, Coquet JM, Boldin MP, Wengel J, Altraja A, Bochenek G, Jakiela B, Rebane A
    Academic press:
    Clinical and Translational Medicine (rok: 2021, tom: 11 (6), strony: e427), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/ctm2.427 - link to the publication
  2. SARS-CoV-2 may regulate cellular responses through depletion of specific host miRNAs
    Authors:
    Bartoszewski R, Dabrowski M, Jakiela B, Matalon S, Harrod KS, Sanak M, Collawn JF
    Academic press:
    merican Journal of Physiology Lung Cellular and Molecular Physiology (rok: 2020, tom: 319, strony: L444-L455), Wydawca: American Physiologic Society
    Status:
    Published
    DOI:
    10.1152/ajplung.00252.2020 - link to the publication
  3. Reduced expression of miR-146a in human bronchial epithelial cells alters neutrophil migration
    Authors:
    Kivihall A, Aab A, Soja J, Sładek K, Sanak M, Altraja A, Jakiela B, Bochenek G, Rebane A
    Academic press:
    Clin Trans Allergy (rok: 2019, tom: 9, strony: 62), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s13601-019-0301-8. - link to the publication
  4. Remodeling of bronchial epithelium caused by asthmatic inflammation affects its response to rhinovirus infection
    Authors:
    Jakiela B, Rebane A, Soja J, Bazan-Socha S, Laanesoo A, Plutecka H, Surmiak M, Sanak M, Sladek K, Bochenek G
    Academic press:
    Scientific Reports (rok: 2021, tom: 11, strony: 12821), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-021-92252-6 - link to the publication
  5. Bronchial epithelial cell transcriptome shows endotype heterogeneity of asthma in NSAID-exacerbated respiratory disease
    Authors:
    Jakiela B, Soja J, Sladek K, Przybyszowski M, Plutecka H, Gielicz A, Licholai S, Aab A, Rebane A, Bochenek G
    Academic press:
    Journal of Allergy and Clinical Immunology , Wydawca: Mosby
    Status:
    Submitted
    DOI:
    brak, - link to the publication

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