Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Materials determinants of biological activity of new generation simple and composite bioactive materials.

2014/13/B/ST8/02973

Keywords:

bioglasses biocomposites bioactivity osteoinduction tissue engineering BMP bone morphogenetic protein bone marrow stem cells

Descriptors:

  • ST8_8: Mechanics of solids
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • NZ1_8: Tissue engineering

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Akademia Górniczo-Hutnicza im. Stanisława Staszica w Krakowie, Wydział Inżynierii Materiałowej i Ceramiki

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Maria Borczuch-Łączka 

Number of co-investigators in the project: 7

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 979 150 PLN

Project start date (Y-m-d): 2015-01-28

Project end date (Y-m-d): 2019-01-27

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Stacjonarny przyrząd do pomiaru chropowatości Hommel-Etamic T8000 (60 000 PLN)
  2. maszyna wytrzymałościowa Zwick Roell (80 000 PLN)

Information in the final report

  • Publication in academic press/journals (14)
  • Articles in post-conference publications (23)
  1. Bioactivity of PLGA-gel-derived bioglass composites
    Authors:
    Maria Łączka, Ewelina Maślanka, Justyna Pawlik, Michał Dziadek, Barbara Zagrajczuk, Katarzyna Cholewa-Kowalska
    Academic press:
    Science, Technology and Innovation (rok: 2018, tom: 3 (2), strony: 27-34), Wydawca: State Higher Vocational School in Tarnow
    Status:
    Published
    DOI:
    10.5604/01.3001.0012.8153 - link to the publication
  2. Biodegradable ceramic-polymer composites for biomedical applications: A review
    Authors:
    Michal Dziadek, Ewa Stodolak-Zych, Katarzyna Cholewa-Kowalska
    Academic press:
    Materials Science and Engineering C Materials for Biological Applications (rok: 2017, tom: 71, strony: 1175–1191), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.014 - link to the publication
  3. Pectin-bioactive glass self-gelling, injectable composites with high antibacterial activity
    Authors:
    Timothy E.L. Douglas, Michal Dziadek, Josefien Schietse, Matthieu Boone, Heidi A. Declercq, Tom Coenye, Valérie Vanhoorne, Chris Vervaet, Lieve Balcaen, Maria Buchweitz, Frank Vanhaecke, Frederic Van Assche, Katarzyna Cholewa-Kowalska, Andre G. Skirtach
    Academic press:
    Carbohydrate Polymers (rok: 2019, tom: 205, strony: 427-436), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.061 - link to the publication
  4. Ectopic bone formation by gel-derived bioactive glass-poly-L-lactide-co-glycolide composites in a rabbit muscle mode
    Authors:
    Joanna Filipowska, Katarzyna Cholewa-Kowalska, Jarosław Wieczorek, Danuta Semik, Zbigniew Dąbrowski, Maria Łączka, Anna M. Osyczka
    Academic press:
    Biomedical Materials (rok: 2017, tom: 1 (12) 015015, strony: 15015), Wydawca: IOPScience
    Status:
    Published
    DOI:
    10.1088/1748-605X/aa4eb7 - link to the publication
  5. A simple way of modulating in vitro angiogenic response using Cu and Co-doped bioactive glasses
    Authors:
    Michal Dziadek, Barbara Zagrajczuk, Elzbieta Menaszek, Kinga Dziadek, Katarzyna Cholewa-Kowalska
    Academic press:
    Materials Letters (rok: 2018, tom: 215, strony: 87–90), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.matlet.2017.12.075 - link to the publication
  6. Gel-derived SiO2–CaO–P2O5 bioactive glasses and glass-ceramics modified by SrO addition
    Authors:
    Michal Dziadeka, Barbara Zagrajczuk, Elzbieta Menaszek, Anna Wegrzynowicz, Justyna Pawlik, Katarzyna Cholewa-Kowalska
    Academic press:
    Ceramics International (rok: 2016, tom: 42, strony: 5842-5857), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2015.12.128 - link to the publication
  7. New generation poly(ε-caprolactone)/gel-derived bioactive glass composites for bone tissue engineering: Part I. Material properties
    Authors:
    Michal Dziadek, Elzbieta Menaszek, Barbara Zagrajczuk, Justyna Pawlik, Katarzyna Cholewa-Kowalska
    Academic press:
    Materials Science and Engineering: C Materials for Biological Applications (rok: 2015, tom: 56, strony: 45556), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2015.06.020 - link to the publication
  8. Structural and chemical investigation of the gel-derived bioactive materials from the SiO2–CaO and SiO2-CaO-P2O5 systems
    Authors:
    Barbara Zagrajczuka, Michal Dziadek, Zbigniew Olejniczak, Katarzyna Cholewa-Kowalska, Maria Laczka
    Academic press:
    Ceramics International (rok: 2017, tom: 43, strony: 12742–12754), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2017.06.160 - link to the publication
  9. The role of CaO/SiO2 ratio and P2O5 content in gel-derived bioactive glasspolymer composites in the modulation of their bioactivity and osteoinductivity in human BMSCs
    Authors:
    K. Łukowicz, B. Zagrajczuk, A. Nowak, Ł. Niedźwiedzki, M. Laczka, K. Cholewa-Kowalska, AM Osyczka
    Academic press:
    Materials Science and Engineering C (rok: 2020, tom: 109, strony: 110535), Wydawca: Elesevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.110535 - link to the publication
  10. Novel injectable gellan gum hydrogel composites incorporating Zn- and Sr-enriched bioactive glass microparticles: high-resolution X-ray microcomputed tomography, antibacterial and in vitro testing
    Authors:
    Timothy E.L. Douglas, Michal Dziadek, Svetlana Gorodzha, Jana Lišková, Gilles Brackman, Valérie Vanhoorne, Chris Vervaet, Lieve Balcaen, Maria del Rosario Florez Garcia, Aldo R. Boccaccini, Venera Weinhardt, Tilo Baumbach, Frank Vanhaecke, Tom Coenye, Lucie Bačáková, Maria A. Surmeneva, Roman A. Surmenev, Katarzyna Cholewa‐Kowalska, Andre G. Skirtach
    Academic press:
    Journal of Tissue Engineering and Regenerative Medicine (rok: 2018, tom: 12 (6), strony: 1313–1326), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/term.2654 - link to the publication
  11. Structural variations of bioactive glasses obtained by different synthesis routes
    Authors:
    Michal Dziadek, BarbaraZagrajczuk, PiotrJelen, ZbigniewOlejniczak, Katarzyna Cholewa-Kowalska
    Academic press:
    Ceramics International (rok: 2016, tom: 42, strony: 14700-14709), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2016.06.095 - link to the publication
  12. Bioactivity and osteoinductivity of glasses and glassceramics and their material determinants
    Authors:
    M. Łączka, K.Cholewa-Kowalska, A.M.Osyczka
    Academic press:
    Ceramics International (rok: 2016, tom: 42, strony: 14313-14325), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ceramint.2016.06.077 - link to the publication
  13. Structural investigation of gel-derived materials from the SiO2-Al2O3 system
    Authors:
    Barbara Zagrajczuka, Michal Dziadek, Zbigniew Olejniczak, Bogda Sulikowski, Katarzyna Cholewa-Kowalska, Maria Laczka
    Academic press:
    Journal of Molecular Structure (rok: 2018, tom: 1167, strony: 23-32), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.molstruc.2018.04.085 - link to the publication
  14. The role of solvent type, size and chemical composition of bioactive glass particles in modulating material properties of poly(e-caprolactone) based composites
    Authors:
    Michal Dziadek, Barbara Zagrajczuk, Magdalena Ziabka, Kinga Dziadek, Katarzyna Cholewa-Kowalska
    Academic press:
    Composites Part A: Applied Science and Manufacturing (rok: 2016, tom: 90, strony: 90-99), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.compositesa.2016.07.001 - link to the publication
  1. A NEW STRONTIUM AND ZINC DOPED BIOGLASSES FOR TISSUE ENGINEERING
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Elzbieta Menaszek, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    26th Conference on Biomaterials in Medicine and Veterinary Medicine (rok: 2017, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 12-15 października
    Status:
    Published
  2. Osteogenic Effects of Short, Steady Media Perfusion in hBMSC 3D Cultures Depend on Cell Culture and Cell Differentiation Stage and a Scaffold Type
    Authors:
    Joanna Filipowska, Justyna Pawlik, Katarzyna Cholewa-Kowalska, Maria Laczka, Anna M. Osyczka
    Conference:
    27th European Conference on Biomaterials (rok: 2015, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 30.08-03.09
    Status:
    Published
  3. Structural investigation on the gel-derived bioglasses from the SiO2- CaO and the SiO2- CaO – P2O5 systems
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Zbigniew Olejniczak, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    IX International Scientific & Technological Conference: Polish Ceramics 2016 (rok: 2016, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 11-14.09
    Status:
    Published
  4. A new cerium doped bioglasses for bone tissue engineering
    Authors:
    •Barbara ZAGRAJCZUK, Michał DZIADEK, Agnieszka Sobol, Katarzyna CHOLEWA-KOWALSKA, Maria ŁĄCZKA
    Conference:
    7th European Young Engineers Conference (rok: 2018, ), Wydawca: Warsaw University of Technology
    Data:
    konferencja 23-25 kwietnia
    Status:
    Published
  5. CuO doped gel-derived bioglasses with potential osteogenic, angiogenic and antibacterial properties
    Authors:
    Michal Dziadek, Barbara Zagrajczuk, Michal Palczynski, Filip Rybczynski, Katarzyna Cholewa-Kowalska
    Conference:
    IX International Scientific & Technological Conference: Polish Ceramics 2016 (rok: 2016, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 11-14.09
    Status:
    Published
  6. Effect of Solvent Type on Material Properties of Solution-cast Poly(ε-Caprolactone) Films
    Authors:
    Michal Dziadek, Barbara Zagrajczuk, Katarzyna Cholewa-Kowalska
    Conference:
    27th European Conference on Biomaterials (rok: 2015, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 30.08-03.09
    Status:
    Published
  7. Effect of heat treatment on the structure of gel derived material from the SiO2-Al2O3 system
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Klaudia Chciuk, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    XIVth INTERNATIONAL CONFERENCE ON MOLECULAR SPECTROSCOPY (rok: 2017, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 3-7 września
    Status:
    Published
  8. How Synthesis Method Affects Bioglass Properties?
    Authors:
    Michał Dziadek, Barbara Zagrajczuk, Kamil Karwat, Justyna Pawlik, Maria Łączka, Katarzyna Cholewa-Kowalska
    Conference:
    27th European Conference on Biomaterials (rok: 2015, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 30.08-03.09
    Status:
    Published
  9. Ocena wpływu składu chemicznego bioszkieł pochodzenia żelowego na włąściwości bioaktywne kompozytów polimerowo-ceramicznych do zastosowań w inżynierii tkankowej
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Katarzyna Cholewa-Kowalska, Maria Łączka
    Conference:
    Doktoranckie Sympozjum Nanotechnologii NanoMat (rok: 2017, ), Wydawca: Wydawnictwo Politechniki Łódzkiej
    Data:
    konferencja 19-20 czerwca
    Status:
    Published
  10. Effect of materials surface and chemical properties on cells activity and elasticity in vitro characterized with AFM microscopy
    Authors:
    Barbara Zagrajczuk, Michał Dziadek, Elzbieta Menaszek, Barbara Orzechowska, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    XLIII Annual Congress of the European Society for Artificial Organs (rok: 2016, ), Wydawca: The International Journal of Artificial Organs, Wichtig
    Data:
    konferencja 14-17.09
    Status:
    Published
  11. Effect of the bioactive glass chemical composition on the bioactivity and degradation rate of polymerceramics composites
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    IX International Scientific & Technological Conference: Polish Ceramics 2016 (rok: 2016, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 11-14.09
    Status:
    Published
  12. Ocena wpływu obróbki termicznej na właściwości bioaktywne szkieł i szkło-ceramiki z układów SiO2−CaO i SiO2−CaO−P2O5
    Authors:
    Barbara ZAGRAJCZUK, Michał DZIADEK, Karol Jartym, Katarzyna CHOLEWA-KOWALSKA, Maria ŁĄCZKA
    Conference:
    NABIOMA 2018 : NanoBioMateriały – teoria i praktyka (rok: 2018, ), Wydawca: Uniwersytet Mikołaja kopernika w Toruniu
    Data:
    konferencja 6–8 czerwca
    Status:
    Published
  13. Twenty years of research on gel-derived CaO-P2O5-SiO2 bioactive glasses - what next?
    Authors:
    Anna Maria Osyczka, Katarzyna Cholewa-Kowalska, Maria Łączka
    Conference:
    25th Anniversary Conference on Biomaterials (rok: 2016, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 13-16.10
    Status:
    Published
  14. Early osteogenic response of human BMSC on polymer based-bioactive glass composites of different composition
    Authors:
    Krzysztof Łukowicz, Barbara Zagrajczuk, Katarzyna Cholewa-Kowalska, Maria Laczka and AM Osyczka
    Conference:
    4th International Conference of Cell Biology (rok: 2018, ), Wydawca: Uniwersytet Jagielloński
    Data:
    konferencja 11-12 maj
    Status:
    Published
  15. Osteoinductive properties of gel-derived binary CaO-SiO2 and ternary CaO-P2O5-SiO2 bioactive glasses
    Authors:
    Kalina Andrysiak, Katarzyna Cholewa-Kowalska, Maria Łączka, Anna Maria Osyczka
    Conference:
    25th Anniversary Conference on Biomaterials (rok: 2016, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 13-16.10
    Status:
    Published
  16. The influence of bioactive glass materials texture on the biomimetic apatite formation
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Karol Jartym, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    VI International Conference of Biophysics Students (rok: 2017, ), Wydawca: Jagiellonian University
    Data:
    konferencja 19-21 Maj
    Status:
    Published
  17. The influence of incubation media on surface properties of bioglass-polymer composites
    Authors:
    Agata FLIS, Barbara ZAGRAJCZUK, Michał DZIADEK, Katarzyna CHOLEWA-KOWALSKA, Maria ŁĄCZKA
    Conference:
    27th annual conference on Biomaterials in medicine and veterinary medicine (rok: 2018, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 11-14 października
    Status:
    Published
  18. The influence of the heat treatment on the chemical activity of the glasses and glass-ceramics from the SiO2-CaO and SiO2-CaO-P2O5 systems
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Karol Jartym, Katarzyna Cholewa-Kowalska, Maria Laczka
    Conference:
    20-th Polish Conference on Biocybernetics and Biomedical Engineering (rok: 2017, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 20-22 września
    Status:
    Published
  19. Influence of chemical compositions on the structure and the bioactive properties of SiO2 - CaO and SiO2 - CaO - P2O5 bioactive glasses
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Katarzyna Cholewa-Kowalska, Maria Łączka
    Conference:
    25th Anniversary Conference on Biomaterials (rok: 2016, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 13-16.10
    Status:
    Published
  20. Materials Determinants of Biological Activity of New Polymer-Based Composites Modified by Gel-Derived Bioglasses
    Authors:
    Barbara Zagrajczuk, Michal Dziadek, Justyna Pawlik, Joanna Filipowska, Amadeusz Bryła, Katarzyna Cholewa-Kowalska, Anna Maria Osyczka, Maria Łączka
    Conference:
    27th European Conference on Biomaterials (rok: 2015, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 30.08-03.09
    Status:
    Published
  21. Osteogenic differentiation and response to osteogenic materials of human adipose tissue-derived cell line Asc52Telo
    Authors:
    Karolina Lelek,Barabara Zagrajczuk, Katarzyna Cholewa-Kowalska, Maria Laczka, Anna M. Osyczka
    Conference:
    4th International Conference of Cell Biology (rok: 2018, ), Wydawca: Uniwersytet Jagielloński
    Data:
    konferencja 11-12 maj
    Status:
    Published
  22. Synthesis method affects the structure of bioactive glasses - FTIR, Raman, NMR and XPS investigation
    Authors:
    Michal Dziadek, Barbara Zagrajczuk, Piotr Jelen, Zbigniew Olejniczak, Katarzyna Cholewa-Kowalska
    Conference:
    IX International Scientific & Technological Conference: Polish Ceramics 2016 (rok: 2016, ), Wydawca: AGH University of Science and Technology
    Data:
    konferencja 11-14.09
    Status:
    Published
  23. Various approaches to the in vitro bioactivity evaluation of the polymer-ceramics composites for bone tissue engineering
    Authors:
    Barbara ZAGRAJCZUK, Michał DZIADEK, Agata Flis, Katarzyna CHOLEWA-KOWALSKA, Maria ŁĄCZKA
    Conference:
    4th international conference on Biomedical polymers & polymeric biomaterials (rok: 2018, ), Wydawca: Polish Society for Biomaterials
    Data:
    konferencja 15-17 lipiec
    Status:
    Published

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