Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Searching for hydrodynamic interactions orientational effects in the kinetics of bio-molecular association

2014/13/B/ST4/03011

Keywords:

encounter complex diffusional encounter rate constant electrostatic and hydrodynamic interactions ionic strength stopped-flow spectroscopy nanosecond laser flash photolysis spectroscopy circular dichroism spectroscopy Brownian dynamics simulations numerical analysis of progress curves

Descriptors:

  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST4_3: Molecular architecture and structure
  • ST6_13: Bioinformatics, biocomputing, DNA and molecular computation

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Warszawski, Wydział Fizyki

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Jan Antosiewicz 

Number of co-investigators in the project: 5

Call: OPUS 7 - announced on 2014-03-17

Amount awarded: 890 240 PLN

Project start date (Y-m-d): 2015-03-13

Project end date (Y-m-d): 2020-03-12

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. spektrometr zatrzymanego przepływu (280 000 PLN)
  2. modernizacja spektrometru LKS60 (Applied Photophysics Ltd.) do wersji LKS80 (110 000 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  1. Searching for hydrodynamic orienting effects in the association of tri-N-acetylglucosamine with hen egg- white lysozyme
    Authors:
    Wielgus-Kutrowska, Beata Marcisz, Urszula Antosiewicz, Jan
    Academic press:
    The Journal of Physical Chemistry , Wydawca: American Chemical Society
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Diffusional Encounter Rate Constants for Xanthone and 2‐Naphthoic Acid by Flash Photolysis Experiments and Brownian Dynamics Simulations: Substantial Effects of Polarizability of the Triplet State
    Authors:
    K. Stachurska, P. Grochowski, J. M. Antosiewicz
    Academic press:
    The Journal of Physical Chemistry B (rok: 2019, tom: 123, strony: 9328-9342), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.9b07989 - link to the publication
  3. Does Ionic Screening Lower Activation Barriers for Conformational Transitions in Proteins?
    Authors:
    Jan Antosiewicz, Maciej Długosz
    Academic press:
    The Journal of Physical Chemistry B (rok: 2018, tom: 122, strony: 11817−11826), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.jpcb.8b07525 - link to the publication
  1. ELECTROSTATIC INTERACTION EFFECTS IN THE KINETICS OF CONFORMATIONAL TRANSITIONS OF PROTEINS
    Authors:
    Jan Antosiewicz
    Conference:
    XVII Conference of the Polish Biophysical Society, Olsztyn (rok: 2019, ), Wydawca: Polskie Towarzystwo Biofizyczne
    Data:
    konferencja June 24 – 27, 2019
    Status:
    Published
  2. BINDING OF N-ACETYLCHITOTRIOSE BY WILD TYPE LYSOZYME AND ITS MUTANT WITH CHANGED DIPOLE MOMENT AS A FUNCTION OF IONIC STRENGTH
    Authors:
    B. Wielgus-Kutrowska, U. Marcisz, J. Antosiewicz
    Conference:
    XVII Conference of the Polish Biophysical Society Olsztyn (rok: 2019, ), Wydawca: Polskie Towarzystwo Biofizyczne
    Data:
    konferencja June 24 – 27, 2019
    Status:
    Published

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