Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Functional analysis of HSPB8 i model organisms (Danio rerio, Drosophila melanogaster): getting insights into HSPB8-linked human pathologies

2014/13/D/NZ4/02038

Keywords:

small heat shock protein myogenesis neuro-muscular diseases zebrafish Drosophila melanogaster

Descriptors:

  • NZ4_5: Anatomical pathology
  • NZ3_13: Developmental biology in animals
  • NZ3_1: Cell biology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Wrocławski, Wydział Nauk Biologicznych

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magda Dubińska-Magiera 

Number of co-investigators in the project: 4

Call: SONATA 7 - announced on 2014-03-17

Amount awarded: 447 300 PLN

Project start date (Y-m-d): 2015-03-04

Project end date (Y-m-d): 2018-03-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Zestaw do elektroforezy z modułem do blotów i zasilaczem (18 000 PLN)
  2. Wyciągarka do pipet (puller) (18 000 PLN)
  3. Cieplarka (7 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (2)
  1. Zebrafish: A Model for the Study of Toxicants Affecting Muscle Development and Function
    Authors:
    Magda Dubińska-Magiera, Małgorzata Daczewska, Anna Lewicka, Marta Migocka-Patrzałek, Joanna Niedbalska-Tarnowska and Krzysztof Jagla
    Academic press:
    International Journal of Molecular Sciences (rok: 2016, tom: 17, strony: 1941), Wydawca: International Journal of Molecular Sciences
    Status:
    Published
    DOI:
    10.3390/ijms17111941 - link to the publication
  2. Developmental Expression and Functions of the Small Heat Shock Proteins in Drosophila
    Authors:
    Teresa Jagla, Magda Dubińska-Magiera, Poovathumkadavil P, Malgorzata Daczewska, Krzysztof Jagla
    Academic press:
    International Journal of Molecular Science (rok: 2018, tom: Nov 2;19(11), strony: pii: E3441), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19113441 - link to the publication
  3. Characterization of Hspb8 in Zebrafish
    Authors:
    Magda Dubińska-Magiera, Joanna Niedbalska-Tarnowska, Marta Migocka-Patrzałek, Ewelina Posyniak and Małgorzata Daczewska
    Academic press:
    Cells (rok: 2020, tom: 9(6), 1562, strony: 9(6), 1562), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells9061562 - link to the publication
  4. Drosophila Hsp67Bc hot-spot variants alter muscle structure and function
    Authors:
    Jadwiga Jabłońska, Magda Dubińska-Magiera*, Teresa Jagla, Krzysztof Jagla, Małgorzata Daczewska
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2018, tom: 75, strony: 4341–4356), Wydawca: Springer International Publishing
    Status:
    Published
    DOI:
    10.1007/s00018-018-2875-z - link to the publication
  1. Distinct outcomes of Charcot-Marie-Tooth (CMT)-causing point mutations in Drosophila small heat shock protein Hsp67Bc
    Authors:
    FEBS JOURNAL
    Conference:
    40th Congress of the Federation-of-European-Biochemical-Societies (FEBS) - The Biochemical Basis of Life (rok: 2015, ), Wydawca: WILEY-BLACKWELL
    Data:
    konferencja 04-09.07
    Status:
    Published
  2. Functional orthologs of human small heat shock protein HSPB8: Drosophila melanogaster Hsp67Bc and Danio rerio HSPB8.
    Authors:
    Magda Dubinska-Magiera, Jadwiga Jabłońska, Ewelina Posyniak, Krzysztof Jagla, Małgorzata Daczewska
    Conference:
    XXXII Conference on Embryology Plants Animals Humans (rok: 2016, ), Wydawca: ACTA BIOLOGICA CRACOVIENSIA Series Botanica the Polish Academy of Sciences
    Data:
    konferencja 18-21.05.2016
    Status:
    Published