Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Investigation of the role of Prox1 and PDPN , classic limphagiogenesis markers in intracellular signaling pathways involved in the metastasis of thyroid carcinoma cells.

2013/11/N/NZ5/03394

Keywords:

thyroid cancer metastasis Prox1 PDPN lymphangiogenesis

Descriptors:

  • NZ5_1: Etiology of human diseases
  • NZ3_14: Other related subjects
  • NZ2_12: Other related subjects

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Centrum Medyczne Kształcenia Podyplomowego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Magdalena Rudzińska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 147 160 PLN

Project start date (Y-m-d): 2014-07-30

Project end date (Y-m-d): 2017-07-29

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (4)
  1. Transcription Factor Prospero Homeobox 1 (PROX1) as a Potential Angiogenic Regulator of Follicular Thyroid Cancer Dissemination
    Authors:
    Magdalena Rudzinska, Michał Mikula, Katarzyna D. Arczewska, Ewa Gajda, Stanisława Sabalinska , Tomasz Stepien, Jerzy Ostrowski and Barbara Czarnocka
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 2019, 20, 5619, strony: 2019, 20, 5619), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20225619 - link to the publication
  2. Molecular Signature of Prospero Homeobox 1 (PROX1) in Follicular Thyroid Carcinoma Cells.
    Authors:
    Rudzińska M., Grzanka M., Stachurska A., Mikula M., Paczkowska K., Stępień T., Paziewska A., Ostrowski J., Czarnocka B.
    Academic press:
    International Journal of Molecular Sciences (rok: 2019, tom: 20(9), 2212, strony: 20(9), 2212), Wydawca: International Journal of Molecular Sciences MDPI
    Status:
    Published
    DOI:
    10.3390/ijms20092212. - link to the publication
  1. Role of homeobox transcription factor PROX1 in follicular thyroid cancer metastasis
    Authors:
    Rudzińska M., Ledwoń A., Karpińska K., Macios M., Krasuska W., Czarnocka B.
    Conference:
    17th International Congress of Endocrinology in collaboration with the 15th Annual Meeting of the Chinese Society of Endocrinology (ICE-CSE 2016) (rok: 2016, ), Wydawca: 17th International Congress of Endocrinology in collaboration with the 15th Annual Meeting of the Chinese Society of Endocrinology (ICE-CSE 2016)
    Data:
    konferencja 31 August - 4 September 2016
    Status:
    Published
  2. The role of the transcription factor - prospero homeobox 1 (Prox1) in the biology of differentiated thyroid tumors
    Authors:
    Magdalena Rudzińska, Damian Gaweł, Kamila Karpińska, Mirosław Kiedrowski, Tomasz Stępień, Magdalena Marchlewska, Hanna Domek, Wanda Krasuska, Anna Łyczkowska, Joanna Drozdowska, Barbara Czarnocka
    Conference:
    7th International Conference of Contemporary Oncology (rok: 2015, ), Wydawca: Contemporary Oncology Współczesna Onkologia
    Data:
    konferencja 25-27.03
    Status:
    Published
  3. Prox1 transcription factor is differentially expressed in thyroid cancer and contributes to the regulation of invasion and migration of thyroid cancer cells
    Authors:
    Magdalena Rudzińska Damian Gaweł, Kamila Karpińska, Mirosław Kiedrowski, Tomasz Stępień, Magdalena Marchlewska, Wanda Krasuska, Joanna Ledwoń, Maria Macios, Dariusz Lange, Barbara Czarnocka
    Conference:
    17th European Congress of Endocrinology 2015 (rok: 2015, ), Wydawca: Endocrine Abstracts published by bioscientifica
    Data:
    konferencja 16-20.05
    Status:
    Published
  4. Role of homeobox transcription factor PROX1 in follicular thyroid cancer metastasis; correlation between PROX1 and AKT kinase signaling pathway
    Authors:
    Rudzińska M., Ledwoń A., Karpińska K., Macios M., Sikorska J., Czarnocka B.
    Conference:
    5th Congress of the Polish Thyroid Association, Poznan, 3-5 September, 2015 (rok: 2015, ), Wydawca: Thyroid Research
    Data:
    konferencja 3-5.09
    Status:
    Published