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Remodeling plasma membrane lipid rafts as a tool to restore normal functions of skeletal muscle cells

2013/11/B/NZ5/03106

Keywords

Descriptors

  • NZ5_1: Etiologia chorób człowieka
  • NZ5_3: Patogeneza chorób człowieka
  • NZ5_7: Leczenie chorób człowieka

Panel

NZ5 – Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Wydział Medycyny Weterynaryjnej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Arkadiusz Bernard Orzechowski

Number of co-investigators in the project: 5

Call

OPUS 6 – announced on 2013-09-16

Amount awarded
865 800 PLN
Project start date
2014-07-18
Project end date
2018-02-17
Project duration
43 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (4)

  1. Artificial meat? Feasible approach based on the experience from cell culture studies.

    Authors:
    Orzechowski Arkadiusz
    Academic press:
    Journal of Integrative Agriculture (year: 2015, volume: 14, pages: 217–221), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/S2095-3119(14)60882-0 – link to the publication

  2. The Many Faces of Rap1 GTPase

    Authors:
    Jaśkiewicz Anna, Pajak Beata, Orzechowski Arkadiusz
    Academic press:
    International Journal of Molecular Sciences (year: 2018, volume: 19, pages: 2848), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19102848 – link to the publication

  3. Diverse Action of Selected Statins on Skeletal Muscle Cells - An Attempt to Explain the Protective Effect of Geranylgeraniol (GGOH) in Statin-Associated Myopathy (SAM)

    Authors:
    Jaśkiewicz Anna, Pajak Beata, Łabieniec-Watała Magdalena, De Palma Clara, Orzechowski Arkadiusz
    Academic press:
    Journal of Clinical Medicine (year: 2019, volume: 8, pages: 694), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/jcm8050694 – link to the publication

  4. Geranylgeraniol prevents statin-dependent myotoxicity in C2C12 muscle cells through RAP1 GTPase prenylation and cytoprotective autophagy

    Authors:
    Anna Jaśkiewicz, Beata Pająk, Anna Litwiniuk, Kaja Urbańska, Arkadiusz Orzechowski
    Academic press:
    Oxidative Medicine and Cellular Longevity (year: 2018, volume: 2018, pages: 22 pages), Publisher: Hindawi
    Status:
    Published
    DOI:
    10.1155/2018/6463807 – link to the publication

Articles in post-conference publications (3)

  1. Importance of Plasma Membrane Nanodomains in Muscle Regeneration

    Authors:
    Orzechowski Arkadiusz
    Conference:
    BIT's 8th World Congress of Regenerative Medicine & Stem Cell 2015 (year: 2015, pages: 21), Publisher: BIT
    Date:
    conference 18-20 listopad 2015
    Status:
    Published

  2. Geranylgeraniol (GGOH) and Rap1 GTPase maintain cell viability retarded by statins in skeletal muscle.

    Authors:
    Jaśkiewicz Anna, Litwiniuk Anna, Pająk Beata, Urbańska Kaja, Orzechowski Arkadiusz
    Conference:
    XXVIIth Congress of the Polish Physiological Society (year: 2017, pages: 32), Publisher: Journal of Physiology and Pharmacology
    Date:
    conference 21-23 września
    Status:
    Published

  3. Cytokines in Skeletal Muscle Growth and Decay

    Authors:
    Orzechowski Arkadiusz
    Conference:
    BIT's Annual World Congress of Regenerative Medicine & Stem Cell 2017 (year: 2017, pages: 16), Publisher: BIT
    Date:
    conference 14-16 listopada
    Status:
    Published

Book publications / chapters in book publications (2)

  1. Cytokines in Skeletal Muscle Growth and Decay

    Authors:
    Orzechowski Arkadiusz
    Book:
    Plasticity of Skeletal Muscle. From Molecular Mechanism to Clinical Applications. (year: 2017, volume: 1, pages: 113-140), Publisher: Springer-Nature
    Status:
    Published
    DOI:
    link to the publication

  2. Importance of Plasma Membrane Nanodomains in Skeletal Muscle Regeneration

    Authors:
    Pająk Beata, Orzechowski Arkadiusz
    Book:
    Muscle Cell and Tissue (year: 2015, volume: 5, pages: 107-142), Publisher: Intech
    Status:
    Published
    DOI:
    link to the publication

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