Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Genome-wide ParB -DNA interactions in Pseudomonas aeruginosa

2013/11/B/NZ2/02555

Keywords:

chromosome segregation Pseudomonas aeruginosa ParB-DNA interactions transcriptomic analysis

Descriptors:

  • NZ2_1: Molecular genetics
  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_3: Proteomics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Grażyna Jagura-Burdzy 

Number of co-investigators in the project: 4

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 1 349 800 PLN

Project start date (Y-m-d): 2014-09-01

Project end date (Y-m-d): 2018-08-31

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. komputer z oprogramowaniem (5 000 PLN)
  2. System do PCR w czasie rzeczywistym (180 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (3)
  1. Increased ParB level affects expression of stress response, adaptation and virulence operons and potentiates repression of promoters adjacent to the high affinity binding sites parS3 and parS4 in Pseudomonas aeruginosa
    Authors:
    Adam Kawałek, Krzysztof Gląbski, Aneta Agnieszka Bartosik, Anna Fogtman and Grażyna Jagura-Burdzy
    Academic press:
    PlosOne (rok: 2017, tom: 12(7):e0181726, strony: 12(7):e0181726), Wydawca: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0181726 - link to the publication
  2. Genome sequence ofPseudomonas aeruginosa PAO1161, a PAO1 derivative with the ICEPae1161 integrative and conjugative element
    Authors:
    Kawalek A., Kotecka K., Modrzejewska M., Gawor J., Jagura-Burdzy G., Bartosik A.A.
    Academic press:
    BMC Genomics (rok: 2020, tom: 21, strony: 14), Wydawca: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12864-019-6378-6 - link to the publication
  3. Interaction of ArmZ with the DNA-Binding Domain of MexZ Induces Expression of mexXY Multidrug Efflux Pump Genes and Antimicrobial Resistance in Pseudomonas aeruginosa
    Authors:
    Kawalek A., Modrzejewska M., Zieniuk B., Bartosik A.A., Jagura-Burdzy G.
    Academic press:
    Antimicrobial Agents and Chemotherapy (rok: 2019, tom: 63(12), strony: 63(12)e01199-19), Wydawca: ASM (American Society for Microbiology)
    Status:
    Published
    DOI:
    10.1128/AAC.01199-19 - link to the publication
  4. Pseudomonas aeruginosa partitioning protein ParB acts as a nucleoid-associated protein binding to multiple copies of a parS-related motif
    Authors:
    Adam Kawalek, Aneta A. Bartosik, Krzysztof Glabski and Grazyna Jagura-Burdzy
    Academic press:
    Nucleic Acids Research (rok: 2018, tom: 46, strony: 4592-4606), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gky257 - link to the publication
  1. ParB-DNA interactions in Pseudomonas aeruginosa - implications for chromosome segregation and gene expression regulation
    Authors:
    Aneta A. Bartosik, Krzysztof Glabski, Paulina Kondrat, Sylwia Mikulska and Grazyna Jagura-Burdzy
    Conference:
    5th ASM Conference on Prokaryotic Cell Biology and Development, Washington, DC, USA, (rok: 2015, ), Wydawca: nie dotyczy
    Data:
    konferencja 12 - 16 June
    Status:
    Published
  2. PARTITIONING PROTEIN PARB CONTROLS EXPRESSION OF GENES ADJACENT TO ITS HIGH AFFINITY BINDING SITES PARS3 AND PARS4 IN PSEUDOMONAS AERUGINOSA
    Authors:
    A. Kawalek , K. Glabski , A.A. Bartosik , A. Fogtman , G. Jagura-Burdzy
    Conference:
    7th Congress of European Microbiologists (FEMS), Valencia, Spain, (rok: 2017, ), Wydawca: nie dotyczy
    Data:
    konferencja 9-13 July
    Status:
    Published
  3. GENOME-WIDE ANALYSIS OF PARB BINDING SITES IN PSEUDOMONAS AERUGINOSA
    Authors:
    A.A. Bartosik , K. Glabski , A. Kawalek , G. Jagura-Burdzy
    Conference:
    7th Congress of European Microbiologists (FEMS), Valencia, Spain, (rok: 2017, ), Wydawca: nie dotyczy
    Data:
    konferencja 9-13 July
    Status:
    Published