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Information on the principal investigator and host institution

Information of the project and the call

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Control of the mammary gland cancer associated inflammation by vitamin D and its analogs

2013/11/B/NZ5/00162

Keywords:

mammary gland cancer immune responce metastasis calcitriol tacalcitol vitamin D

Descriptors:

  • NZ6_1: Adaptive and innate immunity
  • NZ5_7: Human disease treatment

Panel:

NZ5 - Human and animal noninfectious diseases: etiology, mechanisms, diagnosis and treatment of diseases, poisonings and injuries (without neurological diseases)

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda PAN

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Joanna Wietrzyk 

Number of co-investigators in the project: 5

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 665 600 PLN

Project start date (Y-m-d): 2014-08-05

Project end date (Y-m-d): 2017-08-04

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (4)
  1. Calcitriol analogues decrease lung metastasis but impair bone metabolism in aged ovariectomized mice bearing 4T1 mammary gland tumours
    Authors:
    Artur Anisiewicz, Beata Filip-Psurska, Agata Pawlik, Anna Nasulewicz-Goldeman, Tomasz Piasecki, Konrad Kowalski, Magdalena Maciejewska, Joanna Jarosz, Joanna Banach, Diana Papiernik, Andrzej Mazur, Andrzej Kutner, Jeanette A. Maier, Joanna Wietrzyk.
    Academic press:
    Aging and Disease (rok: 2019, tom: 10, strony: -), Wydawca: Beijing Magtech Co. Ltd
    Status:
    Published
    DOI:
    10.14336/AD.2018.0921 - link to the publication
  2. Unfavorable effect of calcitriol and its low-calcemic analogs on metastasis of 4T1 mouse mammary gland cancer
    Authors:
    Artur Anisiewicz, Agata Pawlik, Beata Filip-Psurska, Eliza Turlej, Stanisław Dzimira, Magdalena Milczarek, Katarzyna Gdesz, Diana Papiernik, Joanna Jarosz, Dagmara Kłopotowska, Andrzej Kutner, Andrzej Mazur, Joanna Wietrzyk
    Academic press:
    International Journal of Oncology (rok: 2018, tom: 52, strony: 103-126), Wydawca: Spandidos Publications
    Status:
    Published
    DOI:
    10.3892/ijo.2017.4185 - link to the publication
  3. Divergent effect of calcitriol and tacalcitol (PRI-2191) on Th17 cells in 4T1 tumor bearing young and old ovariectomized mice
    Authors:
    Agata Pawlik, Artur Anisiewicz, Beata Filip-Psurska, Dagmara Klopotowska, Magdalena Maciejewska, Andrzej Mazur, Joanna Wietrzyk
    Academic press:
    w recenzji we Frontiers in Immunology (rok: 2019, tom: --, strony: --), Wydawca: Frontiers Media S.A.
    Status:
    Submitted
    DOI:
    brak - link to the publication
  4. Calcitriol and Its Analogs Establish the Immunosuppressive Microenvironment That Drives Metastasis in 4T1 Mouse Mammary Gland Cancer
    Authors:
    Pawlik A, Anisiewicz A, Filip-Psurska B, Nowak M, Turlej E, Trynda J, Banach J, Gretkierewicz P, Wietrzyk J.
    Academic press:
    Int J Mol Sci. (rok: 2018, tom: 19, strony: 2116), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms19072116 - link to the publication
  1. Immunosupressive properities of 1,25(OH)2D3 derivatives in mouse breast cancer model
    Authors:
    Pawlik A, Anisiewicz A, Filip-Psurska B, Turlej E, Milczarek M, Wietrzyk J
    Conference:
    The Tenth Multidisciplinary Conference on Drug Research (rok: 2016, ), Wydawca: Instytut Farmaceutyczny w Warszawie
    Data:
    konferencja May 15-19
    Status:
    Published
  2. Influence of 1,25(OH)2D3 and its analogs – PRI-2191 and PRI-2205 – on invasion and metastasis in Mouse Brest cancer model
    Authors:
    Anisiewicz A, Pawlik A, Filip-Psurska B, Turlej E, Milczarek M, Wietrzyk J
    Conference:
    19th Workshop on Vitamin D (rok: 2016, ), Wydawca: Witamin D Workshop Inc.
    Data:
    konferencja March 29-31
    Status:
    Published
  3. Impact of 1,25(OH)2D3 analogs on inflammation accompaning mammary gland cancer progression
    Authors:
    Pawlik A, Anisiewicz A, Filip-Psurska B, Turlej E, Milczarek M, Wietrzyk J
    Conference:
    19th Workshop on Vitamin D (rok: 2016, ), Wydawca: Witamin D Workshop Inc.
    Data:
    konferencja March 29-31
    Status:
    Published
  4. 1,25(OH)2D3 derivatives – PRI-2191 and PRI-2205 – and their role in progression and metastasis of 4T1 mouse breast cancer
    Authors:
    Anisiewicz A, Pawlik A, Filip-Psurska B, Milczarek M, Turlej E, Wietrzyk J
    Conference:
    The Tenth Multidisciplinary Conference on Drug Research (rok: 2016, ), Wydawca: Instytut Farmaceutyczny w Warszawie
    Data:
    konferencja May 15-19
    Status:
    Published

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