Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Discovery of new functional variants in platelet activation pathways genes contribiuting to risk of ischemic stroke in Polish population

2013/11/B/NZ7/01541

Keywords:

stroke platelets genetic variants next generation sequencing

Descriptors:

  • NZ7_4: Prevention in population health

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Marek Postuła 

Number of co-investigators in the project: 7

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 512 470 PLN

Project start date (Y-m-d): 2014-07-10

Project end date (Y-m-d): 2018-04-09

Project duration:: 45 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. NanoDrop 2000 z oprogramowaniem do analizy i przechowywania danych (55 000 PLN)
  2. MacBook ProDwurdzeniowy procesor Intel Core i5 2,3 GHz 7. generacji, Turbo Boost do 3,6 GHz16 GB pamięci LPDDR3 2133 MHz256 GB pamięci masowej SSDIntel Iris Plus Graphics 640Dwa porty Thunderbolt 3Podświetlana klawiatura (8 001 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Association of frequent genetic variants in platelet activation pathway genes with large-vessel ischemic stroke in Polish population
    Authors:
    3.Postula M, Janicki PK, Milanowski L, Pordzik J, Eyileten C, Karlinski M, Wylezol P, Solarska M, Czlonkowka A, Kurkowska-Jastrzebka I, Sugino S, Imamura Y, Mirowska-Guzel D.
    Academic press:
    Platelets (rok: 2016, tom: 17, strony: 45299), Wydawca: Taylor & Francis Group
    Status:
    Published
    DOI:
    10.1080/09537104.2016.1203404. - link to the publication
  2. Genetic variability of SRC family kinases and its association with platelet hyperreactivity and clinical outcomes: a systematic review.
    Authors:
    Milanowski L, Rasul F, Gajda SN, Eyileten C, Siller-Matula JM, Postula M
    Academic press:
    Curr Pharm Des (rok: 2018, tom: 24, strony: 45304), Wydawca: Betham Science
    Status:
    Published
    DOI:
    10.2174/1381612824666171213105002. - link to the publication
  3. Increased burden of rare deleterious variants of the KCNQ1 gene in patients with large-vessel ischemic stroke
    Authors:
    Piotr K. Janicki, Ceren Eyileten, Victor Ruiz-Velasco, Justyna Pordzik, Anna Czlonkowska, Iwona Kurkowska-Jastrzebska, Shigekazu Sugino, Yuka Imamura-Kawasawa, Dagmara Mirowska-Guzel, Marek Postula
    Academic press:
    Molecular Medicine Reports (rok: 2019, tom: 19, strony: 3263-3272), Wydawca: Spandidos
    Status:
    Published
    DOI:
    10.3892/mmr.2019.9987 - link to the publication

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