Discovery of new functional variants in platelet activation pathways genes contribiuting to risk of ischemic stroke in Polish population

2013/11/B/NZ7/01541

Keywords

Descriptors

  • NZ7_4: Prewencja populacyjna

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Warszawski Uniwersytet Medyczny, I Wydział Lekarski

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Marek Postuła

Number of co-investigators in the project: 7

Call

OPUS 6 – announced on 2013-09-16

Amount awarded
512 470 PLN
Project start date
2014-07-10
Project end date
2018-04-09
Project duration
45 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. MacBook ProDwurdzeniowy procesor Intel Core i5 2,3 GHz 7. generacji, Turbo Boost do 3,6 GHz16 GB pamięci LPDDR3 2133 MHz256 GB pamięci masowej SSDIntel Iris Plus Graphics 640Dwa porty Thunderbolt 3Podświetlana klawiatura. Cost: 8 001 PLN
  2. NanoDrop 2000 z oprogramowaniem do analizy i przechowywania danych. Cost: 55 000 PLN

Information in the final report

Publication in academic press/journals (3)

  1. Genetic variability of SRC family kinases and its association with platelet hyperreactivity and clinical outcomes: a systematic review.

    Authors:
    Milanowski L, Rasul F, Gajda SN, Eyileten C, Siller-Matula JM, Postula M
    Academic press:
    Curr Pharm Des (year: 2018, volume: 24, pages: 46035), Publisher: Betham Science
    Status:
    Published
    DOI:
    10.2174/1381612824666171213105002. – link to the publication
  2. Association of frequent genetic variants in platelet activation pathway genes with large-vessel ischemic stroke in Polish population

    Authors:
    3.Postula M, Janicki PK, Milanowski L, Pordzik J, Eyileten C, Karlinski M, Wylezol P, Solarska M, Czlonkowka A, Kurkowska-Jastrzebka I, Sugino S, Imamura Y, Mirowska-Guzel D.
    Academic press:
    Platelets (year: 2016, volume: 17, pages: 46030), Publisher: Taylor & Francis Group
    Status:
    Published
    DOI:
    10.1080/09537104.2016.1203404. – link to the publication
  3. Increased burden of rare deleterious variants of the KCNQ1 gene in patients with large-vessel ischemic stroke

    Authors:
    Piotr K. Janicki, Ceren Eyileten, Victor Ruiz-Velasco, Justyna Pordzik, Anna Czlonkowska, Iwona Kurkowska-Jastrzebska, Shigekazu Sugino, Yuka Imamura-Kawasawa, Dagmara Mirowska-Guzel, Marek Postula
    Academic press:
    Molecular Medicine Reports (year: 2019, volume: 19, pages: 3263-3272), Publisher: Spandidos
    Status:
    Published
    DOI:
    10.3892/mmr.2019.9987 – link to the publication

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Graphic design and implementation: Jakub Piotrowski