Post-translational mechanisms of regulation of the activity of transcription factors from the Grainyhead-like family in the context of human cancer.

2013/11/B/NZ1/00083

Keywords

Descriptors

  • NZ1_2: Biochemia
  • NZ1_1: Biologia molekularna
  • NZ3_7: Przekaźnictwo sygnału

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Tomasz Michał Wilanowski

Number of co-investigators in the project: 3

Call

OPUS 6 – announced on 2013-09-16

Amount awarded
830 000 PLN
Project start date
2014-07-24
Project end date
2018-07-23
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Information in the final report

Publication in academic press/journals (3)

  1. TFCP2/TFCP2L1/UBP1 transcription factors in cancer.

    Authors:
    Kotarba G, Krzywinska E, Grabowska AI, Taracha A, Wilanowski T
    Academic press:
    Cancer Letters (year: 2018, volume: 420, pages: 72-79), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.canlet.2018.01.078 – link to the publication
  2. Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer.

    Authors:
    Mlacki M, Kikulska A, Krzywinska E, Pawlak M, Wilanowski T
    Academic press:
    Experimental Biology and Medicine (year: 2015, volume: 240, pages: 1396-1401), Publisher: SAGE Publications
    Status:
    Published
    DOI:
    10.1177/1535370215588924 – link to the publication
  3. Threonine 454 phosphorylation in Grainyhead-like 3 is important for its function and regulation by the p38 MAPK pathway

    Authors:
    Krzywinska E, Zorawski MD, Kikulska A, Mlacki M, Kwiatkowska K, Wilanowski T
    Academic press:
    Biochimica et Biophysica Acta - Molecular Cell Research (year: 2018, volume: 1865, pages: 1002-1011), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2018.04.010 – link to the publication

Articles in post-conference publications (1)

  1. The impact of specific single nucleotide polymorphisms on the phosphorylation and function of the GRHL3 transcription factor

    Authors:
    Krzywinska E, Kikulska A, Zorawski M, Mlacki M, Wilanowski T
    Conference:
    3rd EACR Conference - Cancer Genomics (year: 2017, pages: 50), Publisher: European Association for Cancer Research
    Date:
    conference 25-28 czerwca
    Status:
    Published

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