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Information on the principal investigator and host institution

Information of the project and the call

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Post-translational mechanisms of regulation of the activity of transcription factors from the Grainyhead-like family in the context of human cancer.

2013/11/B/NZ1/00083

Keywords:

transcription factors post-translational modifications phosphorylation Grainyhead-like cancer skin cancer

Descriptors:

  • NZ1_2: Biochemistry
  • NZ1_1: Molecular biology
  • NZ3_7: Signal transduction

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Tomasz Wilanowski 

Number of co-investigators in the project: 3

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 830 000 PLN

Project start date (Y-m-d): 2014-07-24

Project end date (Y-m-d): 2018-07-23

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (1)
  1. Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer.
    Authors:
    Mlacki M, Kikulska A, Krzywinska E, Pawlak M, Wilanowski T
    Academic press:
    Experimental Biology and Medicine (rok: 2015, tom: 240, strony: 1396-1401), Wydawca: SAGE Publications
    Status:
    Published
    DOI:
    10.1177/1535370215588924 - link to the publication
  2. TFCP2/TFCP2L1/UBP1 transcription factors in cancer.
    Authors:
    Kotarba G, Krzywinska E, Grabowska AI, Taracha A, Wilanowski T
    Academic press:
    Cancer Letters (rok: 2018, tom: 420, strony: 72-79), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.canlet.2018.01.078 - link to the publication
  3. Threonine 454 phosphorylation in Grainyhead-like 3 is important for its function and regulation by the p38 MAPK pathway
    Authors:
    Krzywinska E, Zorawski MD, Kikulska A, Mlacki M, Kwiatkowska K, Wilanowski T
    Academic press:
    Biochimica et Biophysica Acta - Molecular Cell Research (rok: 2018, tom: 1865, strony: 1002-1011), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2018.04.010 - link to the publication
  1. The impact of specific single nucleotide polymorphisms on the phosphorylation and function of the GRHL3 transcription factor
    Authors:
    Krzywinska E, Kikulska A, Zorawski M, Mlacki M, Wilanowski T
    Conference:
    3rd EACR Conference - Cancer Genomics (rok: 2017, ), Wydawca: European Association for Cancer Research
    Data:
    konferencja 25-28 czerwca
    Status:
    Published

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