Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Integration of biosynthesis and downstream processing of fungal laccases

2013/11/B/ST8/00337

Keywords:

laccase submerged cultivation enzyme purification downstream processing ATPE foam fractionation

Descriptors:

  • ST8_1: Chemical engineering, technical chemistry, environmental engineering, sanitary engineering, engineering of chemical processes

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Łódzka, Wydział Inżynierii Procesowej i Ochrony Środowiska

woj. łódzkie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Stanisław Ledakowicz 

Number of co-investigators in the project: 5

Call: OPUS 6 - announced on 2013-09-16

Amount awarded: 991 900 PLN

Project start date (Y-m-d): 2014-08-04

Project end date (Y-m-d): 2017-08-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Układ do ogniskowania izoelektrycznego.
  2. Układ do elektroforezy białek (25 000 PLN)
  3. Pompa perystaltyczna (2 sztuki).
  4. Wirówka laboratoryjna (30 000 PLN)
  5. Mieszadło magnetyczne 15-stanowiskowe.
  6. System do preparatywnej chromatografii cieczowej białek (400 000 PLN)

Information in the final report

  • Publication in academic press/journals (10)
  • Articles in post-conference publications (7)
  1. Laccase concentration by foam fractionation of Cerrena unicolor and Pleurotus sapidus culture supernatants
    Authors:
    Michał Blatkiewicz, Anna Antecka, Andrzej Górak, Stanisław Ledakowicz
    Academic press:
    Chemical and Process Engineering (rok: 2017, tom: 38 (3), strony: 455-464), Wydawca: Polish Academy of Sciences Committee of Chemical and Process Engineering
    Status:
    Published
    DOI:
    10.1515/cpe-2017-0035 - link to the publication
  2. Modern morphological engineering techniques for improving productivity of filamentous fungi in submerged cultures
    Authors:
    Anna Antecka, Marcin Bizukojć, Stanisław Ledakowicz
    Academic press:
    World Journal of Microbiology and Biotechnology (rok: 2016, tom: 32, strony: 193), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11274-016-2148-7 - link to the publication
  3. Partitioning of laccases derived from Cerrena unicolor and Pleurotus sapidus in polyethylene glycol – phosphate aqueous two–phase systems
    Authors:
    Michał Blatkiewicz, Anna Antecka, Tomasz Boruta, Andrzej Górak, Stanisław Ledakowicz
    Academic press:
    Process Biochemistry (rok: 2018, tom: 67, strony: 165-174), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.procbio.2018.01.011 - link to the publication
  4. Biosynteza lakazy w obecności mineralnych cząstek tlenku glinu w podłożu
    Authors:
    Anna Antecka, Michał Blatkiewicz, Marcin Bizukojć, Stanisław Ledakowicz
    Academic press:
    Inżynieria i Aparatura Chemiczna (rok: 2015, tom: 3, strony: 65-66), Wydawca: SIGMA-NOT sp. z o. o., Wydawnictwo czasopism i książek technicznych
    Status:
    Published
  5. Morphology engineering of basidiomycetes for improved laccase biosynthesis
    Authors:
    Anna Antecka , Michał Blatkiewicz, Marcin Bizukojć, Stanisław Ledakowicz
    Academic press:
    Biotechnology Letters (rok: 2016, tom: 38, strony: 667-672), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s10529-015-2019-6 - link to the publication
  6. Rola inżynierii biochemicznej w rozwoju biotechnologii
    Authors:
    Stanisław Ledakowicz
    Academic press:
    Inżynieria i Aparatura Chemiczna (rok: 2015, tom: 3, strony: 62-64), Wydawca: SIGMA-NOT sp. z o.o. Wydawnictwo czasopism i książek technicznych
    Status:
    Published
  7. Zastosowanie procesu frakcjonowania pianowego do zatężania lakazy z Cerrena unicolor
    Authors:
    Michał Blatkiewicz, Anna Antecka, Stanisław Ledakowicz, Julianne Merz, Andrzej Górak
    Academic press:
    Inżynieria i Aparatura Chemiczna (rok: 2015, tom: 4, strony: 148-149), Wydawca: SIGMA-NOT sp. z o.o., Wydawnictwo czasopism i książek technicznych
    Status:
    Published
  8. Comparison of downstream processing methods in purification of highly active laccase
    Authors:
    Anna Antecka, Michał Blatkiewicz, Tomasz Boruta, Andrzej Górak, Stanisław Ledakowicz
    Academic press:
    Bioprocess and Biosystems Engineering (rok: 2019, tom: b.d., strony: b.d.), Wydawca: Springer Berlin Heidelberg
    Status:
    Published
    DOI:
    10.1007/s00449-019-02160-3 - link to the publication
  9. Continuous laccase concentration in an aqueous two‑phase system
    Authors:
    Michał Blatkiewicz, Anna Antecka, Andrzej Górak, Stanisław Ledakowicz
    Academic press:
    Chemical Papers (rok: 2018, tom: 72, strony: 555-566), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11696-017-0330-5 - link to the publication
  10. Partitioning of Cerrena unicolor laccase activity in an aqueous two-phase system
    Authors:
    Michał Blatkiewicz, Axel Prinz, Andrzej Górak, Stanisław Ledakowicz
    Academic press:
    Chemical and Process Engineering (rok: 2016, tom: 37 (2), strony: 269-280), Wydawca: Polish Academy of Sciences Committee of Chemical and Process Engineering
    Status:
    Published
    DOI:
    10.1515/cpe-2016-0022 - link to the publication
  1. Morphology Engineering of Basidiomycetes for Improved Laccase Biosynthesis
    Authors:
    Anna Antecka, Michał Blatkiewicz, Marcin Bizukojć, Stanisław Ledakowicz
    Conference:
    Global Biotechnology Congress, Boston, USA (rok: 2015, ), Wydawca: b.d.
    Data:
    konferencja 22-25.07.2015
    Status:
    Published
  2. Laccase concentration by foam fractionation of Cerrena unicolor and Pleurotus sapidus culture supernatants
    Authors:
    Michał Blatkiewicz, Anna Antecka, Andrzej Górak, Stanisław Ledakowicz
    Conference:
    The 22nd Polish Conference of Chemical and Process Engineering (rok: 2016, ), Wydawca: Exall
    Data:
    konferencja 5-9.09.2016
    Status:
    Published
  3. Semi-empirical model of continuous laccase concentration in an aqueous two-phase system
    Authors:
    Michał Blatkiewicz, Anna Antecka, Andrzej Górak, Stanisław Ledakowicz
    Conference:
    44th International Conference of the Slovak Society of Chemical Engineering (rok: 2017, ), Wydawca: Slovak Society of Chemical Engineering, Bratislava
    Data:
    konferencja 22-26.05.2017
    Status:
    Published
  4. Concentration of laccase by continuous foam fractionation
    Authors:
    Anna Ewiak, Michał Blatkiewicz, Anna Antecka, Andrzej Górak, Stanisław Ledakowicz
    Conference:
    Interfacial Phenomena in Theory and Practice (rok: 2017, ), Wydawca: Gdansk University of Technology
    Data:
    konferencja 25-30.06.2017
    Status:
    Published
  5. Continuous methods of fungal laccase concentration
    Authors:
    Michał Blatkiewicz, Anna Antecka, Stanisław Ledakowicz, Andrzej Górak
    Conference:
    2nd International Conference on Enzymology and Molecular Biology (rok: 2017, ), Wydawca: Conference Series - America
    Data:
    konferencja 20-21.03.2017
    Status:
    Published
  6. Upstream and downstream processing of fungal laccase
    Authors:
    Anna Antecka, Michał Blatkiewicz, Paweł Gluszcz, Stanisław Ledakowicz, Andrzej Gorak
    Conference:
    2nd International Conference on Enzymology and Molecular Biology (rok: 2017, ), Wydawca: Conference Series - America
    Data:
    konferencja 20-21.03.2017
    Status:
    Published
  7. Differences in Cerrena unicolor and Pleurotus sapidus laccase partitioning in polyethylene glycol - phosphate aqueous two-phase systems
    Authors:
    Michał Blatkiewicz, Anna Antecka, Andrzej Górak, Stanisław Ledakowicz
    Conference:
    17th European Congress on Biotechnology (rok: 2016, ), Wydawca: Elsevier
    Data:
    konferencja 3-6.07.2016
    Status:
    Published