Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Synthesis, physico-chemical and biological studies on macromolecular carriers of antimicrobial peptides

2013/11/N/NZ7/02342

Keywords:

antimicrobial peptides polymeric carriers of drugs biomaterials enzymatic ring-opening polymerization biodegradable and bioresorbable polymers ionic liquids microwave radiation

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Urszula Piotrowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 6 - announced on 2013-09-16

Amount awarded: 139 880 PLN

Project start date (Y-m-d): 2014-08-21

Project end date (Y-m-d): 2018-10-20

Project duration:: 50 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (6)
  1. Current state of a dual behaviour of antimicrobial peptides— Therapeutic agents and promising delivery vectors
    Authors:
    Urszula Piotrowska, Marcin Sobczak, Ewa Oledzka
    Academic press:
    Chemical Biology & Drug Design (rok: 2017, tom: 90, strony: 1079–1093), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/cbdd.13031 - link to the publication
  2. Effect of ionic liquids on the structural, thermal, and in vitro degradation properties of poly(e-caprolactone) synthesized in the presence of Candida antarctica lipase B
    Authors:
    Urszula Piotrowska, Marcin Sobczak, Ewa Oledzka, Christèle Combes
    Academic press:
    Journal of Applied Polymer Science (rok: 2016, tom: 133, strony: 45301), Wydawca: Wiley-Blackwell
    Status:
    Published
    DOI:
    10.1002/app.43728 - link to the publication
  3. A Novel Delivery System for the Controlled Release of Antimicrobial Peptides: Citropin 1.1 and Temporin A
    Authors:
    Urszula Piotrowska, Ewa Oledzka, Anna Zgadzaj, Marta Bauer, Marcin Sobczak
    Academic press:
    Polymers (rok: 2018, tom: 10, strony: 45304), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym10050489 - link to the publication
  4. Enzymatic Polymerization of Cyclic Monomers in Ionic Liquids as a Prospective Synthesis Method for Polyesters Used in Drug Delivery Systems
    Authors:
    Urszula Piotrowska, Marcin Sobczak
    Academic press:
    Molecules (rok: 2015, tom: 20, strony: 45314), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules20010001 - link to the publication
  5. The Effect of Polymer Microstructure on Encapsulation Efficiency and Release Kinetics of Citropin 1.1 from the Poly(e-caprolactone) Microparticles
    Authors:
    Urszula Piotrowska, Ewa Oledzka, Wojciech Kamysz, Sławomir Białek, Marcin Sobczak
    Academic press:
    Nanomaterials (Basel) (rok: 2018, tom: 8, strony: 45301), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano8070482 - link to the publication
  1. Biodegradable medical devices for the controlled release of antimicrobial peptides
    Authors:
    Urszula Piotrowska, Marcin Sobczak
    Conference:
    3rd Central European Biomedical Congress (rok: 2018, ), Wydawca: finansowane przez MNiSW w ramach programu Dialog
    Data:
    konferencja 15-18.09
    Status:
    Published
  2. Enzymatic polymerization of cyclic monomers in ionic liquids as promising synthesis method of matrices for drug delivery systems
    Authors:
    Urszula Piotrowska, Marcin Sobczak, Ewa Oledzka
    Conference:
    28th European Conference on Biomaterials ESB2017 (rok: 2017, ), Wydawca: European Society for Biomaterials
    Data:
    konferencja 4-8.09
    Status:
    Published
  3. Preparation of Biomedical Poly(ε-caprolactone) via Ring Opening Polymerization Catalyzed by Candida Antarctica Lipase B In Ionic Liquids
    Authors:
    Urszula Piotrowska, Marcin Sobczak, Ewa Olędzka
    Conference:
    27th European Conference on Biomaterials ESB2015 (rok: 2015, ), Wydawca: Scientific Publishing House "Akapit"
    Data:
    konferencja 30.08-03.09.2015
    Status:
    Published
  4. Synthesis and characterization of biodegradable macromolecular conjugates of antimicrobial peptides
    Authors:
    Urszula Piotrowska, Marcin Sobczak, Ewa Oledzka
    Conference:
    28th European Conference on Biomaterials ESB2017 (rok: 2017, ), Wydawca: European Society for Biomaterials
    Data:
    konferencja 04-08.09
    Status:
    Published
  5. Development, structural and biological evaluation of polymeric carriers of temporin A as a new antimicrobial delivery system
    Authors:
    Urszula Piotrowska, Marcin Sobczak
    Conference:
    Chemistry for Beauty and Health (rok: 2018, ), Wydawca: Wydawnictwo Naukowe UMK
    Data:
    konferencja 13-16.06
    Status:
    Published
  6. Preparation and characterization of poly(ε-caprolactone) microparticles containing antimicrobial peptides for treatment of local infections
    Authors:
    Urszula Piotrowska, Marcin Sobczak
    Conference:
    Biomaterials and Novel Technologies for Healthcare, 2nd International Biennial Conference BioMaH (rok: 2018, ), Wydawca: National Research Council
    Data:
    konferencja 8-11.09
    Status:
    Published

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