Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Mitotic regulatory pathways in Drosophila melanogaster - proteomic analysis

2013/10/M/NZ2/00298

Keywords:

cell division mitosis kinetochore centrosome mitotic spindle Drosophila mass spectrometry proteomics kinase phosphatase substrate posttranslational modification mutliprotein complex Mis12 CENP-C Spc105 Polo Plk1 Plk4

Descriptors:

  • NZ1_1: Molecular biology
  • NZ2_1: Molecular genetics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Michał Dadlez 

Number of co-investigators in the project: 6

Call: HARMONIA 5 - announced on 2013-06-14

Amount awarded: 945 880 PLN

Project start date (Y-m-d): 2014-06-04

Project end date (Y-m-d): 2017-06-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (3)
  1. Network of protein interactions within the Drosophila inner kinetochore
    Authors:
    Magdalena Richter, Jaroslaw Poznanski, Anna Zdziarska, Mariusz Czarnocki-Cieciura, Zoltan Lipinszki, Michal Dadlez, David Glover, Marcin Przewloka
    Academic press:
    Open biology (rok: 2016, tom: 2, strony: 45309), Wydawca: Royal Society
    Status:
    Published
    DOI:
    10.1098/rsob.150238 - link to the publication
  2. The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins.
    Authors:
    Edlich-Muth C, Artero JB, Callow P, Przewloka MR, Watson AA, Zhang W, Glover DM, Debski J, Dadlez M, Round AR, Forsyth VT, Laue ED
    Academic press:
    J Mol Biol (rok: 2015, tom: 427 (10), strony: 1949-63), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmb.2015.03.010 - link to the publication
  3. Plk4 phosphorylates Ana2 to trigger Sas6 recruitment and procentriole formation
    Authors:
    Nikola S. Dzhindzhev, George Tzolovsky, Zoltan Lipinszki, Sandra Schneider, Ramona Lattao, Jingyan Fu, Janusz Debski, Michal Dadlez, David M. Glover
    Academic press:
    Current Biology (rok: 2014, tom: 24(21), strony: 2526-32), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cub.2014.08.061 - link to the publication

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