Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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Exploiting the potential of synchrotron radiation for high resolution and weak signal in macromolecular crystallography

2013/10/M/NZ1/00251

Keywords:

macromolecular crystallography high resolution atomic resolution anomalous signal synchrotron radiation,

Descriptors:

  • NZ1_4: Structural biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Chemii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Mariusz Jaskólski 

Number of co-investigators in the project: 7

Call: HARMONIA 5 - announced on 2013-06-14

Amount awarded: 721 500 PLN

Project start date (Y-m-d): 2014-05-19

Project end date (Y-m-d): 2018-01-18

Project duration:: 44 months (the same as in the proposal)

Project status: Project settled

Information in the final report

  • Publication in academic press/journals (17)
  1. Atomic-resolution structure of a chimeric DNA-RNA Z-type duplex in complex with Ba2+ ions: a case of complicated multi-domain twinning
    Authors:
    Miroslaw Gilski, Pawel Drozdzal, Ryszard Kierzek and Mariusz Jaskolski
    Academic press:
    Acta Cryst. D (rok: 2016, tom: 72, strony: 211-223), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S2059798315024365 - link to the publication
  2. Mechanochemical Encapsulation of Fullerenes in Peptidic Containers Prepared by Dynamic Chiral Self-Sorting and Self-Assembly
    Authors:
    Marek Szymanski, Michal Wierzbicki, Mirosław Gilski, Hanna Jedrzejewska, Marcin Sztylko, Piotr Cmoch, Aleksander Shkurenko, Mariusz Jaskolski and Agnieszka Szumna
    Academic press:
    Chemistry - A European Journal (rok: 2016, tom: 22, strony: 3148-3155), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1002/chem.201504451 - link to the publication
  3. ANS complex of St John's wort PR-10 protein with 28 copies in the asymmetric unit: a fiendish combination of superstructure modulation with tetartohedral twinning
    Authors:
    Joanna Sliwiak, Zbigniew Dauter, Marcin Kowiel, Airlie J. McCoy, Randy J. Read, Mariusz Jaskolski
    Academic press:
    Acta Cryst. D (rok: 2015, tom: 71, strony: 829-843), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S1399004715001388 - link to the publication
  4. An enzyme captured in two conformational states: crystal structure of S-adenosyl-L-homocysteine hydrolase from Bradyrhizobium elkanii
    Authors:
    Tomasz Manszewski, Kriti Singh, Barbara Imiolczyk, Mariusz Jaskolski
    Academic press:
    Acta Cryst. D (rok: 2015, tom: 71, strony: 2422-2432), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S1399004715018659 - link to the publication
  5. Detect, correct, retract: How to manage incorrect structural models.
    Authors:
    Wlodawer A, Dauter Z, Porebski PJ, Minor W, Stanfield R, Jaskolski M, Pozharski E, Weichenberger CX, Rupp B
    Academic press:
    FEBS Journal (rok: 2018, tom: 285, strony: 444-466), Wydawca: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
    Status:
    Published
    DOI:
    10.1111/febs.14320 - link to the publication
  6. Protonation and geometry of histidine rings
    Authors:
    Maura Malinska, Miroslawa Dauter, Marcin Kowiel, Mariusz Jaskolski, Zbigniew Dauter
    Academic press:
    Acta Cryst. D (rok: 2015, tom: 71, strony: 1444-1454), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S1399004715007816 - link to the publication
  7. Structure of γ-conglutin: insight into the quaternary structure of 7S basic globulins from legumes
    Authors:
    Jaroslaw Czubinski, Jakub Barciszewski, Miroslaw Gilski, Kamil Szpotkowski, Janusz Debski, Eleonora Lampart-Szczapa, Mariusz Jaskolski
    Academic press:
    Acta Cryst. D (rok: 2015, tom: 71, strony: 224-238), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S1399004714025073 - link to the publication
  8. Four highly pseudosymmetric and/or twinned structures of d(CGCGCG)2 extend the repertoire of crystal structures of Z-DNA.
    Authors:
    Luo Z, Dauter Z, Gilski M.
    Academic press:
    Acta Crystallogr D Struct Biol. (rok: 2017, tom: 73, strony: 940-951), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S2059798317014954 - link to the publication
  9. PR-10 proteins as potential mediators of melatonin-cytokinin cross-talk in plants: crystallographic studies of LlPR-10.2B isoform from yellow lupine.
    Authors:
    J.Sliwiak, M.Sikorski, M.Jaskolski
    Academic press:
    FEBS Journal (rok: 2018, tom: 285, strony: 1907-1922), Wydawca: WILEY, 111 RIVER ST, HOBOKEN 07030-5774, NJ USA
    Status:
    Published
    DOI:
    10.1111/febs.14455 - link to the publication
  10. Prior knowledge or freedom of interpretation? A critical look at a recently published classification of novel" Zn binding sites
    Authors:
    Joanna Raczynska, Alexander Wlodawer and Mariusz Jaskolski
    Academic press:
    Proteins: Structure, Function, and Bioinformatics (rok: 2016, tom: 84, strony: 770-776), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1002/prot.25024 - link to the publication
  11. ACHESYM: an algorithm and server for standardized placement of macromolecular models in the unit cell
    Authors:
    Marcin Kowiel, Mariusz Jaskolski and Zbigniew Dauter
    Academic press:
    Acta Cryst. D (rok: 2014, tom: 70, strony: 3290–3298), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S1399004714024572 - link to the publication
  12. Conformation-dependent restraints for polynucleotides: I. Clustering of the geometry of the phosphodiester group
    Authors:
    Marcin Kowiel, Dariusz Brzezinski and Mariusz Jaskolski
    Academic press:
    Nucleic Acids Research (rok: 2016, tom: 44, strony: 8479-8489), Wydawca: Oxford University Press Great Clarendon Street Oxford OX2 6DP
    Status:
    Published
    DOI:
    10.1093/nar/gkw717 - link to the publication
  13. Crystallographic and SAXS studies of S-adenosyl-l-homocysteine hydrolase from Bradyrhizobium elkanii.
    Authors:
    Manszewski T, Szpotkowski K, Jaskolski M.
    Academic press:
    IUCrJ (rok: 2017, tom: 4(Pt 3), strony: 271-282), Wydawca: INT UNION CRYSTALLOGRAPHY, 2 ABBEY SQ, CHESTER, CH1 2HU, ENGLAND
    Status:
    Published
    DOI:
    10.1107/S2052252517002433 - link to the publication
  14. Crystallography and chemistry should always go together: a cautionary tale of protein complexes with cisplatin and carboplatin
    Authors:
    Ivan Shabalin, Zbigniew Dauter, Mariusz Jaskolski, Wladek Minor, Alexander Wlodawer
    Academic press:
    Acta Cryst. D (rok: 2015, tom: 71, strony: 1965-1979), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S139900471500629X - link to the publication
  15. High-resolution crystal structure of Z-DNA in complex with Cr3+ cations
    Authors:
    Pawel Drozdzal, Miroslaw Gilski, Ryszard Kierzek, Lechoslaw Lomozik, and Mariusz Jaskolski
    Academic press:
    J Biol Inorg Chem. (rok: 2015, tom: 20(3), strony: 595–602), Wydawca: SPRINGER 233 SPRING ST, NEW YORK, NY 10013 GERMANY
    Status:
    Published
    DOI:
    10.1007/s00775-015-1247-5 - link to the publication
  16. Crystal structure of Hyp-1, a Hypericum perforatum PR-10 protein, in complex with melatonin
    Authors:
    Joanna Sliwiak, Zbigniew Dauter and Mariusz Jaskolski
    Academic press:
    Frontiers in Plant Science (rok: 2016, tom: 7, strony: 45301), Wydawca: Frontiers EPFL Innovation Park, Building I CH – 1015 Lausanne Switzerland
    Status:
    Published
    DOI:
    10.3389/fpls.2016.00668 - link to the publication
  17. Ultrahigh-resolution centrosymmetric crystal structure of Z-DNA reveals the massive presence of alternate conformations
    Authors:
    Pawel Drozdzal, Miroslaw Gilski and Mariusz Jaskolski
    Academic press:
    Acta Cryst. D (rok: 2016, tom: 72, strony: 1203-1211), Wydawca: WILEY-BLACKWELL 111 RIVER ST, HOBOKEN 07030-5774, NJ, Denmark
    Status:
    Published
    DOI:
    10.1107/S205979831601679X - link to the publication