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Analysis of antioxidative potential of proteins immobilized on nanoparticles. Study in vitro, in vivo

2013/09/B/NZ7/01019

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Medyczny w Łodzi, Katedra Biochemii Medycznej

Voivodeship: łódzkie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Janusz Zbigniew Szemraj

Number of co-investigators in the project: 7

Call

OPUS 5 – announced on 2013-03-15

Amount awarded
964 277 PLN
Project start date
2014-06-09
Project end date
2018-06-08
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Equipment purchased [PL]

  1. Zestaw do elektroforezy zawierający: zasilacz, system do elektroforezy poziomej, system do analizy i dokumentacji żeli wraz z odpowiednim oprogramowaniem.. Cost: 40 000 PLN

Information in the final report

Publication in academic press/journals (10)

  1. A study of the activity of recombinant Mn-superoxide dismutase in the presence of gold and silver nanoparticles

    Authors:
    Agnieszka Małgorzata Pudlarz , Katarzyna Ranoszek-Soliwoda, Ewa Czechowska, Emilia Tomaszewska, Grzegorz Celichowski, Jarosław Grobelny, Janusz Szemraj
    Academic press:
    Appl Biochem Biotechnol (year: 2019, volume: 187, pages: 1551-1568), Publisher: Spinger
    Status:
    Published
    DOI:
    10.1007/s12010-018-2896-y – link to the publication

  2. The effect of immobilized antioxidant enzymes on the oxidative stress in UV-irradiated rat skin

    Authors:
    Pudlarz AM, Czechowska E, S Karbownik M, Ranoszek-Soliwoda K, Tomaszewska E, Celichowski G, Grobelny J, Chabielska E, Gromotowicz-Popławska A, Szemraj J.
    Academic press:
    Nanomedicine (Lond) (year: 2020, volume: 15(1), pages: 23-39), Publisher: Future Medicine Ltd
    Status:
    Published
    DOI:
    10.2217/nnm-2019-0166. – link to the publication

  3. Immobilization of Recombinant Human Catalase on Gold and Silver Nanoparticles.

    Authors:
    Pudlarz AM, Czechowska E, Ranoszek-Soliwoda K, Tomaszewska E, Celichowski G, Grobelny J, Szemraj J.
    Academic press:
    Appl Biochem Biotechnol (year: 2018, volume: 184, pages: 46041), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s12010-017-2682-2 – link to the publication

  4. Catalase-modified gold nanoparticles: Determination of the degree of protein adsorption by gel electrophoresis

    Authors:
    . Katarzyna Ranoszek-Soliwoda, Ewa Czechowska, Emilia Tomaszewska, Grzegorz Celichowski, Tomasz Kowalczyk, Tomasz Sakowicz, Janusz Szemraj, Jarosław Grobelny
    Academic press:
    Colloids Surf B Biointerfaces (year: 2017, volume: 159, pages: 533-539), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2017.08.019. – link to the publication

  5. Hairy roots culture as a source of valuable biopharmaceuticals.

    Authors:
    Kowalczyk T, Łucka M, Szemraj J, Sakowicz T.
    Academic press:
    Postepy Hig Med Dosw (year: 2016, volume: 5; 70, pages: 46031), Publisher: Instytut Immunologii i Terapii Doświadczalnej PAN
    Status:
    Published
    DOI:
    10.5604/17322693.1192186 – link to the publication

  6. Therapeutic potential of secondary metabolites produced in the hairy roots cultures.

    Authors:
    Kowalczyk T, Łucka M, Szemraj J, Sakowicz T.
    Academic press:
    Postepy Hig Med Dosw (Online). (year: 2015, volume: 4;69, pages: 549-61), Publisher: Instytut Immunologii i Terapii Doświadczalnej PAN
    Status:
    Published
    DOI:
    10.5604/17322693.1151285 – link to the publication

  7. Differences in corona formation of catalase immobilised on gold and silver nanoparticles

    Authors:
    Katarzyna Ranoszek-Soliwoda; Ewa Czechowska; Emilia Tomaszewska; Agnieszka Pudlarz; Janusz Szemraj; Grzegorz Celichowski; Jaroslaw Grobelny
    Academic press:
    Colloids and Surfaces A: Physicochemical and Engineering Aspects (year: 2020, volume: 600, pages: xx), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfa.2020.125003 – link to the publication

  8. Plants as an alternative source of therapeutic proteins.

    Authors:
    Łucka M, Kowalczyk T, Szemraj J, Sakowicz T.
    Academic press:
    Postepy Hig Med Dosw (Online). (year: 2015, volume: 4;69, pages: 362-73), Publisher: Instytut Immuologii i Terapii Doświadczalnej PAN
    Status:
    Published
    DOI:
    10.5604/17322693.1145824 – link to the publication

  9. Comparison of the antioxidant activity of catalase immobilized on gold nanoparticles via specific and non-specific adsorption

    Authors:
    Czechowska E., Ranoszek-Soliwoda K., Tomaszewska E., Pudlarz A., Celichowski G., Gralak-Zwolenik D., Szemraj J., Grobelny J.
    Academic press:
    Colloids and Surfaces B: Biointerfaces (year: 2018, volume: 18, pages: 30483-1.), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.colsurfb.2018.07.036 – link to the publication

  10. Nanoparticles as carriers of proteins, peptides and therapeutic molecules

    Authors:
    Pudlasz A, Szemraj J
    Academic press:
    Open Life Sciences (year: 2018, volume: 13, pages: 285–298), Publisher: De Gruyter
    Status:
    Published
    DOI:
    10.1515/biol-2018-0035 – link to the publication

Articles in post-conference publications (3)

  1. Białka immobilizowane na nanocząstkach - okreslenie stopnia obsadzenia z wykorzystaniem elektroforezy żelowej

    Authors:
    Katarzyna Ranoszek-Soliwoda, Ewa Czechowska, Emilia Tomaszewska, Grzegorz Celichowski, Janusz Szemraj, Jarosław Grobelny
    Conference:
    VIII Krajowa Konferencja Nanotechnologii. Łódź (year: 2017, pages: s 67), Publisher: Uniwersytet Łódzki
    Date:
    conference Łódź, 2017.06.20
    Status:
    Published

  2. . Porównanie stopnia obsadzenia nanocząsteczek złota i srebra białkiem enzymatycznym-katalazą

    Authors:
    Ewa Czechowska, Katarzyna Ranoszek-Soliwoda, Emilia Tomaszewska, Grzegorz Celichowski, Janusz Szemraj, Jarosław Grobelny
    Conference:
    VIII Krajowa Konferencja Nanotechnologii. Łódź (year: 2017, pages: s 150), Publisher: Uniwersytet Łódzki
    Date:
    conference Łódź, 20-23 czerwca 2017
    Status:
    Published

  3. Badanie aktywności katalazy zaadsorbowanej na powierzchni nanocząsteczek złot

    Authors:
    Ewa Czechowska, Katarzyna Ranoszek-Soliwoda, Emilia Tomaszewska, Grzegorz Celichowski, Janusz Szemraj, Jarosław Grobelny
    Conference:
    VIII Krajowa Konferencja Nanotechnologii. Łódź, 20-23 czerwca 2017 (year: 2017, pages: s. 83), Publisher: Uniwersytet Łódzki
    Date:
    conference Łódź, 2017.06.20
    Status:
    Published

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