Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of mesenteric white adipose tissue and muscle-fat crosstalk on severity of experimental colitis in mice

2013/09/B/NZ4/01566

Keywords:

colitis physical exercise obesity inflammation adipose tissue irisin

Descriptors:

  • NZ5_3: Pathogenesis of human diseases
  • NZ4_2: Physiology

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Uniwersytet Jagielloński – Collegium Medicum, Collegium Medicum, Wydział Lekarski

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Tomasz Brzozowski 

Number of co-investigators in the project: 7

Call: OPUS 5 - announced on 2013-03-15

Amount awarded: 593 750 PLN

Project start date (Y-m-d): 2014-03-19

Project end date (Y-m-d): 2018-03-18

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Bieżnia dla zwierząt (40 000 PLN)
  2. Klatki bytowe z kółkiem (30 000 PLN)
  3. Urządzenie do pomiaru siły kończyn (20 000 PLN)

Information in the final report

  • Publication in academic press/journals (6)
  1. Mechanisms by which Stress Affects the Experimental and Clinical Inflammatory Bowel Disease (IBD): Role of Brain-Gut Axis
    Authors:
    Brzozowski Bartosz, Mazur-Biały Agnieszka, Pajdo Robert, Kwiecień Sławomir, Bilski Jan, Zwolińska Wcisło Małgorzata, Mach Tomasz, Brzozowski Tomasz
    Academic press:
    Current Neuropharmacology (rok: 2016, tom: 14, strony: 892-900.), Wydawca: Bentham Science
    Status:
    Published
    DOI:
    10.2174/1570159X14666160404124127 - link to the publication
  2. New insight into the direct anti-inflammatory activity of a myokine irisin against proinflammatory activation of adipocytes. Implication for exercise in obesity
    Authors:
    Mazur-Bialy Agnieszka I., Bilski Jan, Pochec Ewa, Brzozowski Tomasz
    Academic press:
    Journal of Physiology and Pharmacology (rok: 2017, tom: 68, strony: 243-251), Wydawca: Polish Physiological Society
    Status:
    Published
  3. Beneficial effect of voluntary exercise on experimental colitis in mice fed a high-fat diet: the role of irisin, adiponectin and proinflammatory biomarkers.
    Authors:
    Mazur-Bialy Agnieszka, Bilski Jan, Wojcik Dagmara, Brzozowski Bartosz, Surmiak Marcin, Hubalewska-Mazgaj Magdalena, Chmura Anna, Magierowski Marcin, Magierowska Katarzyna, Mach Tomasz, Brzozowski Tomasz.
    Academic press:
    Nutrients (rok: 2017, tom: 9, strony: 45312), Wydawca: MDPI AG
    Status:
    Published
    DOI:
    10.3390/nu9040410 - link to the publication
  4. Moderate exercise training attenuates the severity of experimental rodent colitis: the importance of crosstalk between adipose tissue and skeletal muscles
    Authors:
    Bilski Jan, Mazur-Bialy Agnieszka I., Brzozowski Bartosz, Magierowski Marcin, Jasnos Katarzyna, Krzysiek-Maczka Gracjana, Urbanczyk Katarzyna, Ptak-Belowska Agata, Zwolinska-Wcislo Malgorzata, Mach Tomasz, Brzozowski Tomas
    Academic press:
    Mediators of Inflammation (rok: 2015, tom: brak, strony: 12), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2015/605071 - link to the publication
  5. Can exercise affect the course of inflammatory bowel disease? Experimental and clinical evidence.
    Authors:
    Bilski Jan, Mazur-Bialy Agnieszka, Brzozowski Bartosz, Magierowski Marcin, Zahradnik-Bilska Janina, Wojcik Dagmara, Magierowska Katarzyna, Kwiecien Slawomir, Mach Tomasz, Brzozowski Tomasz
    Academic press:
    Pharmacological Reports (rok: 2016, tom: vol. 68, strony: 827-836), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.pharep.2016.04.009 - link to the publication
  6. The Role of Physical Exercise in Inflammatory Bowel Disease
    Authors:
    Jan Bilski, Bartosz Brzozowski, Agnieszka Mazur-Bialy, Zbigniew Sliwowski, Tomasz Brzozowski
    Academic press:
    BioMed Research International (rok: 2014, tom: brak, strony: 14), Wydawca: Hindawi Publishing Corporation
    Status:
    Published
    DOI:
    10.1155/2014/429031 - link to the publication