Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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From Symptoms to Treatment: a comprehensive characteristic of the evolution of pathological changes in an experimental model of fatty liver using vibrational spectroscopy imaging

2013/09/N/NZ7/00626

Keywords:

tissue fatty liver high fat diet (HFD) chemical imaging Raman and FT-IR spectroscopy

Descriptors:

  • NZ7_12: Prevention of human diseases
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ7_16: Other related subjects

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Kamila Kochan 

Number of co-investigators in the project: 2

Call: PRELUDIUM 5 - announced on 2013-03-15

Amount awarded: 116 400 PLN

Project start date (Y-m-d): 2014-03-19

Project end date (Y-m-d): 2016-07-18

Project duration:: 28 months (the same as in the proposal)

Project status: Project settled

Equipment purchased [PL]

  1. Części elektroniczne/optyczne/mechaniczne do stosowanych spektrometrów. (1 000 PLN)
  2. Detektor CCD. (30 000 PLN)
  3. Zestaw komputerowy. (3 500 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Book publications / chapters in book publications (1)
  1. Raman spectroscopy analysis of lipid droplets content, distribution and saturation level in Non-Alcoholic Fatty Liver Disease in mice
    Authors:
    K. Kochan, E. Maslak, C. Krafft, R. Kostogrys, S. Chlopicki, M. Baranska
    Academic press:
    Journal of Biophotonics (rok: 2014, tom: -, strony: -), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jbio.201400077 - link to the publication
  2. Comparison of FTIR transmission and transfection substrates for canine liver cancer detection
    Authors:
    K. Kochan, P. Heraud, M. Kiupele, V. Yuzbasiyan-Gurkan, D. McNaughton, M. Baranska, B.R. Wood
    Academic press:
    Analyst (rok: 2014, tom: -, strony: -), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C4AN01901F - link to the publication
  3. Raman spectroscopic studies of vitamin A content in the liver: a biomarker of healthy liver
    Authors:
    K. Kochan, K.M. Marzec, E. Maslak, S. Chlopicki, M. Baranska
    Academic press:
    Analyst (rok: 2014, tom: -, strony: -), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C4AN01878H - link to the publication
  4. FT-IR imaging for quantitative determination of liver fat content in Non-Alcoholic Fatty Liver
    Authors:
    K. Kochan, E. Maslak, S. Chlopicki, M. Baranska
    Academic press:
    Analyst (rok: 2015, tom: 140(15), strony: 4997-5002), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C5AN00737B - link to the publication
  1. Biomedical application of Raman and FI-IR spectroscopy: Label-free imaging of liver insult
    Authors:
    K. Kochan, E. Maslak, M. Baranska
    Book:
    Encyclopedia of Analytical Chemistry (rok: 2017, tom: bd, strony: bd), Wydawca: John Wiley and Sons, Inc
    Status:
    Published

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